Loading...
Sign in to edit your profile (add interests, overview, photo, etc.)

    Costes, Sylvain

    TitleBiophysicist Staff Sci/Engr
    SchoolLawrence Berkeley National Lab
    DepartmentBiological Systems & Eng
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/486-6988
    vCardDownload vCard

      Collapse Bibliographic 
      Collapse Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
      List All   |   Timeline
      1. Paul-Gilloteaux P, Potiron V, Delpon G, Supiot S, Chiavassa S, Paris F, Costes S. Optimizing radiotherapy protocols using computer automata to model tumour cell death as a function of oxygen diffusion processes. Sci Rep. 2017 May 23; 7(1):2280. PMID: 28536438.
        View in: PubMed
      2. Swenson JM, Colmenares SU, Strom AR, Costes S, Karpen GH. The composition and organization of Drosophila heterochromatin are heterogeneous and dynamic. Elife. 2016 Aug 11; 5. PMID: 27514026; PMCID: PMC4981497.
      3. Sridharan DM, Asaithamby A, Blattnig SR, Costes S, Doetsch PW, Dynan WS, Hahnfeldt P, Hlatky L, Kidane Y, Kronenberg A, Naidu MD, Peterson LE, Plante I, Ponomarev AL, Saha J, Snijders AM, Srinivasan K, Tang J, Werner E, Pluth JM. Evaluating biomarkers to model cancer risk post cosmic ray exposure. Life Sci Space Res (Amst). 2016 Jun; 9:19-47. PMID: 27345199.
        View in: PubMed
      4. Adams CJ, Yu JS, Mao JH, Jen KY, Costes S, Wade M, Shoemake J, Aina OH, Del Rosario R, Menchavez PT, Cardiff RD, Wahl GM, Balmain A. The Trp53 delta proline (Trp53?P) mouse exhibits increased genome instability and susceptibility to radiation-induced, but not spontaneous, tumor development. Mol Carcinog. 2016 Sep; 55(9):1387-96. PMID: 26310697; PMCID: PMC4891300 [Available on 09/01/17].
      5. Georgescu W, Osseiran A, Rojec M, Liu Y, Bombrun M, Tang J, Costes S. Characterizing the DNA Damage Response by Cell Tracking Algorithms and Cell Features Classification Using High-Content Time-Lapse Analysis. PLoS One. 2015; 10(6):e0129438. PMID: 26107175; PMCID: PMC4479605.
      6. Tang J, Huang Y, Nguyen DH, Costes S, Snijders AM, Mao JH. Genetic Background Modulates lncRNA-Coordinated Tissue Response to Low Dose Ionizing Radiation. Int J Genomics. 2015; 2015:461038. PMID: 25802832; PMCID: PMC4353441.
      7. Sridharan DM, Asaithamby A, Bailey SM, Costes S, Doetsch PW, Dynan WS, Kronenberg A, Rithidech KN, Saha J, Snijders AM, Werner E, Wiese C, Cucinotta FA, Pluth JM. Understanding cancer development processes after HZE-particle exposure: roles of ROS, DNA damage repair and inflammation. Radiat Res. 2015 Jan; 183(1):1-26. PMID: 25564719.
        View in: PubMed
      8. Illa-Bochaca I, Ouyang H, Tang J, Sebastiano C, Mao JH, Costes S, Demaria S, Barcellos-Hoff MH. Densely ionizing radiation acts via the microenvironment to promote aggressive Trp53-null mammary carcinomas. Cancer Res. 2014 Dec 01; 74(23):7137-48. PMID: 25304265.
        View in: PubMed
      9. Vadhavkar N, Pham C, Georgescu W, Deschamps T, Heuskin AC, Tang J, Costes S. Combinatorial DNA damage pairing model based on X-ray-induced foci predicts the dose and LET dependence of cell death in human breast cells. Radiat Res. 2014 Sep; 182(3):273-81. PMID: 25076115.
        View in: PubMed
      10. Tang J, Fernandez-Garcia I, Vijayakumar S, Martinez-Ruis H, Illa-Bochaca I, Nguyen DH, Mao JH, Costes S, Barcellos-Hoff MH. Irradiation of juvenile, but not adult, mammary gland increases stem cell self-renewal and estrogen receptor negative tumors. Stem Cells. 2014 Mar; 32(3):649-61. PMID: 24038768.
        View in: PubMed
      11. Chiolo I, Tang J, Georgescu W, Costes S. Nuclear dynamics of radiation-induced foci in euchromatin and heterochromatin. Mutat Res. 2013 Oct; 750(1-2):56-66. PMID: 23958412; PMCID: PMC3838906.
      12. Park CC, Georgescu W, Polyzos A, Pham C, Ahmed KM, Zhang H, Costes S. Rapid and automated multidimensional fluorescence microscopy profiling of 3D human breast cultures. Integr Biol (Camb). 2013 Apr; 5(4):681-91. PMID: 23407655; PMCID: PMC3641787.
      13. Nam JM, Ahmed KM, Costes S, Zhang H, Onodera Y, Olshen AB, Hatanaka KC, Kinoshita R, Ishikawa M, Sabe H, Shirato H, Park CC. ß1-Integrin via NF-?B signaling is essential for acquisition of invasiveness in a model of radiation treated in situ breast cancer. Breast Cancer Res. 2013; 15(4):R60. PMID: 23883667; PMCID: PMC3978561.
      14. Dunleavy EM, Beier NL, Gorgescu W, Tang J, Costes S, Karpen GH. The cell cycle timing of centromeric chromatin assembly in Drosophila meiosis is distinct from mitosis yet requires CAL1 and CENP-C. PLoS Biol. 2012; 10(12):e1001460. PMID: 23300382; PMCID: PMC3531500.
      15. Shaffer VA, Boerma M, Buonanno M, Costes S, Criswell T, Gonon G, Pandey BN, Pinto M, Rockwell S. Broadcasting in the airways: the fifth anniversary of the Radiation Research Podcast (1). Radiat Res. 2012 Jul; 178(1):99-100. PMID: 22686863.
        View in: PubMed
      16. Neumaier T, Swenson J, Pham C, Polyzos A, Lo AT, Yang P, Dyball J, Asaithamby A, Chen DJ, Bissell MJ, Thalhammer S, Costes S. Evidence for formation of DNA repair centers and dose-response nonlinearity in human cells. Proc Natl Acad Sci U S A. 2012 Jan 10; 109(2):443-8. PMID: 22184222; PMCID: PMC3258602.
      17. Maxwell CA, Benítez J, Gómez-Baldó L, Osorio A, Bonifaci N, Fernández-Ramires R, Costes S, Guinó E, Chen H, Evans GJ, Mohan P, Català I, Petit A, Aguilar H, Villanueva A, Aytes A, Serra-Musach J, Rennert G, Lejbkowicz F, Peterlongo P, Manoukian S, Peissel B, Ripamonti CB, Bonanni B, Viel A, Allavena A, Bernard L, Radice P, Friedman E, Kaufman B, Laitman Y, Dubrovsky M, Milgrom R, Jakubowska A, Cybulski C, Gorski B, Jaworska K, Durda K, Sukiennicki G, Lubinski J, Shugart YY, Domchek SM, Letrero R, Weber BL, Hogervorst FB, Rookus MA, Collee JM, Devilee P, Ligtenberg MJ, Luijt RB, Aalfs CM, Waisfisz Q, Wijnen J, Roozendaal CE. Interplay between BRCA1 and RHAMM regulates epithelial apicobasal polarization and may influence risk of breast cancer. PLoS Biol. 2011 Nov; 9(11):e1001199. PMID: 22110403; PMCID: PMC3217025.
      18. Andarawewa KL, Costes S, Fernandez-Garcia I, Chou WS, Ravani SA, Park H, Barcellos-Hoff MH. Lack of radiation dose or quality dependence of epithelial-to-mesenchymal transition (EMT) mediated by transforming growth factor ß. Int J Radiat Oncol Biol Phys. 2011 Apr 01; 79(5):1523-31. PMID: 21310544.
        View in: PubMed
      19. Tang J, Enderling H, Becker-Weimann S, Pham C, Polyzos A, Chen CY, Costes S. Phenotypic transition maps of 3D breast acini obtained by imaging-guided agent-based modeling. Integr Biol (Camb). 2011 Apr; 3(4):408-21. PMID: 21373705; PMCID: PMC4009383.
      20. Chiolo I, Minoda A, Colmenares SU, Polyzos A, Costes S, Karpen GH. Double-strand breaks in heterochromatin move outside of a dynamic HP1a domain to complete recombinational repair. Cell. 2011 Mar 04; 144(5):732-44. PMID: 21353298; PMCID: PMC3417143.
      21. Groesser T, Chang H, Fontenay G, Chen J, Costes S, Helen Barcellos-Hoff M, Parvin B, Rydberg B. Persistence of ?-H2AX and 53BP1 foci in proliferating and non-proliferating human mammary epithelial cells after exposure to ?-rays or iron ions. Int J Radiat Biol. 2011 Jul; 87(7):696-710. PMID: 21271785.
        View in: PubMed
      22. Spencer VA, Costes S, Inman JL, Xu R, Chen J, Hendzel MJ, Bissell MJ. Depletion of nuclear actin is a key mediator of quiescence in epithelial cells. J Cell Sci. 2011 Jan 01; 124(Pt 1):123-32. PMID: 21172822; PMCID: PMC3001411.
      23. Rivera JF, Gurlo T, Daval M, Huang CJ, Matveyenko AV, Butler PC, Costes S. Human-IAPP disrupts the autophagy/lysosomal pathway in pancreatic ß-cells: protective role of p62-positive cytoplasmic inclusions. Cell Death Differ. 2011 Mar; 18(3):415-26. PMID: 20814419; PMCID: PMC3132000.
      24. Mukhopadhyay R, Costes S, Bazarov AV, Hines WC, Barcellos-Hoff MH, Yaswen P. Promotion of variant human mammary epithelial cell outgrowth by ionizing radiation: an agent-based model supported by in vitro studies. Breast Cancer Res. 2010; 12(1):R11. PMID: 20146798; PMCID: PMC2880432.
      25. Ghajar CM, Kachgal S, Kniazeva E, Mori H, Costes S, George SC, Putnam AJ. Mesenchymal cells stimulate capillary morphogenesis via distinct proteolytic mechanisms. Exp Cell Res. 2010 Mar 10; 316(5):813-25. PMID: 20067788; PMCID: PMC2845480.
      26. Costes S, Chiolo I, Pluth JM, Barcellos-Hoff MH, Jakob B. Spatiotemporal characterization of ionizing radiation induced DNA damage foci and their relation to chromatin organization. Mutat Res. 2010 Apr-Jun; 704(1-3):78-87. PMID: 20060491; PMCID: PMC3951968.
      27. Ponomarev AL, Costes S, Cucinotta FA. Stochastic properties of radiation-induced DSB: DSB distributions in large scale chromatin loops, the HPRT gene and within the visible volumes of DNA repair foci. Int J Radiat Biol. 2008 Nov; 84(11):916-29. PMID: 19016140.
        View in: PubMed
      28. Maxwell CA, Fleisch MC, Costes S, Erickson AC, Boissière A, Gupta R, Ravani SA, Parvin B, Barcellos-Hoff MH. Targeted and nontargeted effects of ionizing radiation that impact genomic instability. Cancer Res. 2008 Oct 15; 68(20):8304-11. PMID: 18922902.
        View in: PubMed
      29. Barkan D, Kleinman H, Simmons JL, Asmussen H, Kamaraju AK, Hoenorhoff MJ, Liu ZY, Costes S, Cho EH, Lockett S, Khanna C, Chambers AF, Green JE. Inhibition of metastatic outgrowth from single dormant tumor cells by targeting the cytoskeleton. Cancer Res. 2008 Aug 01; 68(15):6241-50. PMID: 18676848; PMCID: PMC2561279.
      30. Andarawewa KL, Erickson AC, Chou WS, Costes S, Gascard P, Mott JD, Bissell MJ, Barcellos-Hoff MH. Ionizing radiation predisposes nonmalignant human mammary epithelial cells to undergo transforming growth factor beta induced epithelial to mesenchymal transition. Cancer Res. 2007 Sep 15; 67(18):8662-70. PMID: 17875706.
        View in: PubMed
      31. Costes S, Ponomarev A, Chen JL, Nguyen D, Cucinotta FA, Barcellos-Hoff MH. Image-based modeling reveals dynamic redistribution of DNA damage into nuclear sub-domains. PLoS Comput Biol. 2007 Aug; 3(8):e155. PMID: 17676951; PMCID: PMC1937017.
      32. Fleisch MC, Maxwell CA, Kuper CK, Brown ET, Barcellos-Hoff MH, Costes S. Intensity-based signal separation algorithm for accurate quantification of clustered centrosomes in tissue sections. Microsc Res Tech. 2006 Dec; 69(12):964-72. PMID: 16941664.
        View in: PubMed
      33. Costes S, Boissière A, Ravani S, Romano R, Parvin B, Barcellos-Hoff MH. Imaging features that discriminate between foci induced by high- and low-LET radiation in human fibroblasts. Radiat Res. 2006 May; 165(5):505-15. PMID: 16669704.
        View in: PubMed
      34. Barcellos-Hoff MH, Costes S. A systems biology approach to multicellular and multi-generational radiation responses. Mutat Res. 2006 May 11; 597(1-2):32-8. PMID: 16417910.
        View in: PubMed
      35. Daelemans D, Costes S, Lockett S, Pavlakis GN. Kinetic and molecular analysis of nuclear export factor CRM1 association with its cargo in vivo. Mol Cell Biol. 2005 Jan; 25(2):728-39. PMID: 15632073; PMCID: PMC543413.
      36. Muriaux D, Costes S, Nagashima K, Mirro J, Cho E, Lockett S, Rein A. Role of murine leukemia virus nucleocapsid protein in virus assembly. J Virol. 2004 Nov; 78(22):12378-85. PMID: 15507624; PMCID: PMC525092.
      37. Daelemans D, Costes S, Cho EH, Erwin-Cohen RA, Lockett S, Pavlakis GN. In vivo HIV-1 Rev multimerization in the nucleolus and cytoplasm identified by fluorescence resonance energy transfer. J Biol Chem. 2004 Nov 26; 279(48):50167-75. PMID: 15294891.
        View in: PubMed
      38. Veitenhansl M, Stegner K, Hierl FX, Dieterle C, Feldmeier H, Gutt B, Landgraf R, Garrow AP, Vileikyte L, Findlow A, Waterman C, Boulton AJ, Shankhdhar K, Shankhdhar L, Shankhdhar U, Petrova NL, Foster AV, Edmonds ME, Ferraresi R, Caravaggi C, De Giglio R, Cavaiani P, Pogliaghi I, Sommariva E, Katz IA, Harlan A, Miranda-Palma B, Prieto-Sanchez L, Armstrong DG, Bowker JH, Mizel MS, Cernea S, Wohlgelernter J, Kidron M, Modi P, Raz I, Arbit E, Nosek L, Kapitza C, Beckett P, Gelfand R, Goldberg M, Heise T, Testa MA, Turner RR, Hayes JF, Scranton RE, Simonson DC, Yang YW, Hsu YJ, Naujok O, Francini F, Jörns A, Tiedge M, Lenzen S, Abdel-Wahab YH, Marenah L, Orr DF, Shaw C, Flatt PR, Chokkalingam K, Mansell PI, Clausen P, Ekbom P, Damm P, Feldt-Rasmussen U, Nielsen B, Mathiesen ER, Feldt-Rasmussen B, Dewan S, Da Silva N, Ternan PM, Leong KS, Wilding JP, Asatiani N, Kurashvili R, Dundua M, Shelestova E, Pagava K, Ramazashvili M, Hod M, Smirnov S, Petersen JL, Justesen TI, Ringholm Nielsen L, Müller C, Højlund K, Wensaas A, Kase ET, Aas V, Rustan AC, Thoresen GH, Levin K, Beck-Nielsen H, Gaster M, Im SS, Kang SY, Kim SY, Ahn YH, Lihn AS, Schmoll D, Werner T, Kienitz A, Meyer M, Barthel A, Ailett F, Sutherland C, Walther R, Grempler R, Sasson S, Reich R, Tenenbaum T, Alpert E, Anfossi G, Russo I, Traversa M, Massucco P, Mattiello L, Doronzo G, Trovati M, Lally S, Tan CY, Owens D, Tomkin GH, Porchay I, Péan F, Bellili N, Betoulle D, Balkau B, Tichet J, Marre M, Fumeron F. 40th EASD Annual Meeting of the European Association for the Study of Diabetes : Munich, Germany, 5-9 September 2004. Diabetologia. 2004 Aug; 47(Suppl 1):A1-A464. PMID: 27770180.
        View in: PubMed
      39. Costes S, Daelemans D, Cho EH, Dobbin Z, Pavlakis G, Lockett S. Automatic and quantitative measurement of protein-protein colocalization in live cells. Biophys J. 2004 Jun; 86(6):3993-4003. PMID: 15189895; PMCID: PMC1304300.
      40. Catalfamo M, Karpova T, McNally J, Costes S, Lockett SJ, Bos E, Peters PJ, Henkart PA. Human CD8+ T cells store RANTES in a unique secretory compartment and release it rapidly after TcR stimulation. Immunity. 2004 Feb; 20(2):219-30. PMID: 14975243.
        View in: PubMed
      41. Yang HS, Jansen AP, Komar AA, Zheng X, Merrick WC, Costes S, Lockett SJ, Sonenberg N, Colburn NH. The transformation suppressor Pdcd4 is a novel eukaryotic translation initiation factor 4A binding protein that inhibits translation. Mol Cell Biol. 2003 Jan; 23(1):26-37. PMID: 12482958; PMCID: PMC140682.
      42. Ortiz De Solórzano C, Costes S, Callahan DE, Parvin B, Barcellos-Hoff MH. Applications of quantitative digital image analysis to breast cancer research. Microsc Res Tech. 2002 Oct 15; 59(2):119-27. PMID: 12373722.
        View in: PubMed
      43. Costes S, Barcellos-Hoff MH. Radiation quality and tissue-specific microenvironments following exposure to 1 GeV/amu Fe. Adv Space Res. 2002; 30(4):865-70. PMID: 12530433.
        View in: PubMed
      44. Costes S, Sachs R, Hlatky L, Vannais D, Waldren C, Fouladi B. Large-mutation spectra induced at hemizygous loci by low-LET radiation: evidence for intrachromosomal proximity effects. Radiat Res. 2001 Nov; 156(5 Pt 1):545-57. PMID: 11604068.
        View in: PubMed
      45. Costes S, Streuli CH, Barcellos-Hoff MH. Quantitative image analysis of laminin immunoreactivity in skin basement membrane irradiated with 1 GeV/nucleon iron particles. Radiat Res. 2000 Oct; 154(4):389-97. PMID: 11023602.
        View in: PubMed

      A U.S. Department of Energy National Laboratory Managed by the University of California

      This site is running Profiles RNS version v2.10.0-410-g1c0064ed.