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Elliott, John

TitleEnvir Sustainability Manager
InstitutionLawrence Berkeley National Lab
DepartmentLaboratory Directorate
Address1 Cyclotron Road
Berkeley CA 94720
Phone510/486-7188
vCardDownload vCard

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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    1. Xu H, Lu H, Xu Z, Luan L, Li C, Xu Y, Dong K, Zhang J, Li X, Li Y, Liu G, Gong S, Zhao YG, Liu A, Zhang Y, Zhang W, Cai X, Xiang JN, Elliott J, Lin X. Discovery of CNS Penetrant CXCR2 Antagonists for the Potential Treatment of CNS Demyelinating Disorders. ACS Med Chem Lett. 2016 Apr 14; 7(4):397-402. PMID: 27096048; PMCID: PMC4834652 [Available on 04/14/17].
    2. Wang Y, Yang T, Liu Q, Ma Y, Yang L, Zhou L, Xiang Z, Cheng Z, Lu S, Orband-Miller LA, Zhang W, Wu Q, Zhang K, Li Y, Xiang JN, Elliott J, Leung S, Ren F, Lin X. Discovery of N-(4-aryl-5-aryloxy-thiazol-2-yl)-amides as potent ROR?t inverse agonists. Bioorg Med Chem. 2015 Sep 01; 23(17):5293-302. PMID: 26277758.
      View in: PubMed
    3. Wang Y, Cai W, Cheng Y, Yang T, Liu Q, Zhang G, Meng Q, Han F, Huang Y, Zhou L, Xiang Z, Zhao YG, Xu Y, Cheng Z, Lu S, Wu Q, Xiang JN, Elliott J, Leung S, Ren F, Lin X. Discovery of Biaryl Amides as Potent, Orally Bioavailable, and CNS Penetrant ROR?t Inhibitors. ACS Med Chem Lett. 2015 Jul 09; 6(7):787-92. PMID: 26191367; PMCID: PMC4499822.
    4. Lu H, Yang T, Xu Z, Wren PB, Zhang Y, Cai X, Patel M, Dong K, Zhang Q, Zhang W, Guan X, Xiang J, Elliott J, Lin X, Ren F. 2-Aminopyrimidin-4(1H)-one as the novel bioisostere of urea: discovery of novel and potent CXCR2 antagonists. Bioorg Med Chem Lett. 2014 Dec 01; 24(23):5493-6. PMID: 25455491.
      View in: PubMed
    5. Wang Y, Cai W, Zhang G, Yang T, Liu Q, Cheng Y, Zhou L, Ma Y, Cheng Z, Lu S, Zhao YG, Zhang W, Xiang Z, Wang S, Yang L, Wu Q, Orband-Miller LA, Xu Y, Zhang J, Gao R, Huxdorf M, Xiang JN, Zhong Z, Elliott J, Leung S, Lin X. Discovery of novel N-(5-(arylcarbonyl)thiazol-2-yl)amides and N-(5-(arylcarbonyl)thiophen-2-yl)amides as potent ROR?t inhibitors. Bioorg Med Chem. 2014 Jan 15; 22(2):692-702. PMID: 24388993.
      View in: PubMed
    6. Yang T, Liu Q, Cheng Y, Cai W, Ma Y, Yang L, Wu Q, Orband-Miller LA, Zhou L, Xiang Z, Huxdorf M, Zhang W, Zhang J, Xiang JN, Leung S, Qiu Y, Zhong Z, Elliott J, Lin X, Wang Y. Discovery of Tertiary Amine and Indole Derivatives as Potent ROR?t Inverse Agonists. ACS Med Chem Lett. 2014 Jan 09; 5(1):65-8. PMID: 24900774; PMCID: PMC4027777.
    7. Deng G, Zhao B, Ma Y, Xu Q, Wang H, Yang L, Zhang Q, Guo TB, Zhang W, Jiao Y, Cai X, Zhang J, Liu H, Guan X, Lu H, Xiang J, Elliott J, Lin X, Ren F. Novel complex crystal structure of prolyl hydroxylase domain-containing protein 2 (PHD2): 2,8-Diazaspiro[4.5]decan-1-ones as potent, orally bioavailable PHD2 inhibitors. Bioorg Med Chem. 2013 Nov 01; 21(21):6349-58. PMID: 24055079.
      View in: PubMed
    8. Deng G, Meng Q, Liu Q, Xu X, Xu Q, Ren F, Guo TB, Lu H, Xiang JN, Elliott J, Lin X. Identification of benzoxazole analogs as novel, S1P(3) sparing S1P(1) agonists. Bioorg Med Chem Lett. 2012 Jun 15; 22(12):3973-7. PMID: 22583616.
      View in: PubMed
    9. Ren F, Deng G, Wang H, Luan L, Meng Q, Xu Q, Xu H, Xu X, Zhang H, Zhao B, Li C, Guo TB, Yang J, Zhang W, Zhao Y, Jia Q, Lu H, Xiang JN, Elliott J, Lin X. Discovery of novel 1,2,4-thiadiazole derivatives as potent, orally active agonists of sphingosine 1-phosphate receptor subtype 1 (S1P(1)). J Med Chem. 2012 May 10; 55(9):4286-96. PMID: 22500954.
      View in: PubMed
    10. Meng Q, Zhao B, Xu Q, Xu X, Deng G, Li C, Luan L, Ren F, Wang H, Xu H, Xu Y, Zhang H, Xiang JN, Elliott J, Guo TB, Zhao Y, Zhang W, Lu H, Lin X. Indole-propionic acid derivatives as potent, S1P3-sparing and EAE efficacious sphingosine-1-phosphate 1 (S1P1) receptor agonists. Bioorg Med Chem Lett. 2012 Apr 15; 22(8):2794-7. PMID: 22429468.
      View in: PubMed
    11. Xu H, Zhang H, Luan L, Xu Y, Li C, Wang Y, Han F, Yang T, Ren F, Xiang JN, Elliott J, Zhao Y, Guo TB, Lu H, Zhang W, Hirst D, Lindon M, Lin X. Discovery of thiadiazole amides as potent, S1P3-sparing agonists of sphingosine-1-phosphate 1 (S1P1) receptor. Bioorg Med Chem Lett. 2012 Apr 01; 22(7):2456-9. PMID: 22386243.
      View in: PubMed
    12. Wan Z, Hall A, Sang Y, Xiang JN, Yang E, Smith B, Harrison DC, Yang G, Yu H, Price HS, Wang J, Hawkins J, Lau LF, Johnson MR, Li T, Zhao W, Mitchell WL, Su X, Zhang X, Zhou Y, Jin Y, Tong Z, Cheng Z, Hussain I, Elliott J, Matsuoka Y. Pyridine-derived ?-secretase modulators. Bioorg Med Chem Lett. 2011 Aug 15; 21(16):4832-5. PMID: 21742495.
      View in: PubMed
    13. Wan Z, Hall A, Jin Y, Xiang JN, Yang E, Eatherton A, Smith B, Yang G, Yu H, Wang J, Ye L, Lau LF, Yang T, Mitchell W, Cai W, Zhang X, Sang Y, Wang Y, Tong Z, Cheng Z, Hussain I, Elliott J, Matsuoka Y. Pyridazine-derived ?-secretase modulators. Bioorg Med Chem Lett. 2011 Jul 01; 21(13):4016-9. PMID: 21636276.
      View in: PubMed
    14. Qian X, McDonald A, Zhou HJ, Adams ND, Parrish CA, Duffy KJ, Fitch DM, Tedesco R, Ashcraft LW, Yao B, Jiang H, Huang JK, Marin MV, Aroyan CE, Wang J, Ahmed S, Burgess JL, Chaudhari AM, Donatelli CA, Darcy MG, Ridgers LH, Newlander KA, Schmidt SJ, Chai D, Colón M, Zimmerman MN, Lad L, Sakowicz R, Schauer S, Belmont L, Baliga R, Pierce DW, Finer JT, Wang Z, Morgan BP, Morgans DJ, Auger KR, Sung CM, Carson JD, Luo L, Hugger ED, Copeland RA, Sutton D, Elliott J, Jackson JR, Wood KW, Dhanak D, Bergnes G, Knight SD. Discovery of the First Potent and Selective Inhibitor of Centromere-Associated Protein E: GSK923295. ACS Med Chem Lett. 2010 Apr 08; 1(1):30-4. PMID: 24900171; PMCID: PMC4007900.
    15. Nie H, Widdowson KL, Palovich MR, Fu W, Elliott J, Bryan DL, Burman M, Schmidt DB, Foley JJ, Sarau HM, Busch-Petersen J. N,N'-Diarylcyanoguanidines as antagonists of the CXCR2 and CXCR1 chemokine receptors. Bioorg Med Chem Lett. 2006 Nov 01; 16(21):5513-6. PMID: 16934456.
      View in: PubMed
    16. Ohlstein EH, Johnson AG, Elliott J, Romanic AM. New strategies in drug discovery. Methods Mol Biol. 2006; 316:1-11. PMID: 16671397.
      View in: PubMed
    17. Jin Q, Nie H, McCleland BW, Widdowson KL, Palovich MR, Elliott J, Goodman RM, Burman M, Sarau HM, Ward KW, Nord M, Orr BM, Gorycki PD, Busch-Petersen J. Discovery of potent and orally bioavailable N,N'-diarylurea antagonists for the CXCR2 chemokine receptor. Bioorg Med Chem Lett. 2004 Sep 06; 14(17):4375-8. PMID: 15357956.
      View in: PubMed
    18. Widdowson KL, Elliott J, Veber DF, Nie H, Rutledge MC, McCleland BW, Xiang JN, Jurewicz AJ, Hertzberg RP, Foley JJ, Griswold DE, Martin L, Lee JM, White JR, Sarau HM. Evaluation of potent and selective small-molecule antagonists for the CXCR2 chemokine receptor. J Med Chem. 2004 Mar 11; 47(6):1319-21. PMID: 14998320.
      View in: PubMed

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