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    Keasling, Jay

    TitleChemist Senior Faculty SE
    SchoolLawrence Berkeley National Lab
    DepartmentLaboratory Directorate
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/495-2620
    vCardDownload vCard

      Collapse Bibliographic 
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. de Rond T, Stow P, Eigl I, Johnson RE, Chan LJG, Goyal G, Baidoo EEK, Hillson NJ, Petzold CJ, Sarpong R, Keasling J. Oxidative cyclization of prodigiosin by an alkylglycerol monooxygenase-like enzyme. Nat Chem Biol. 2017 Sep 11. PMID: 28892091.
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      2. Morrell WC, Birkel GW, Forrer M, Lopez T, Backman TWH, Dussault M, Petzold CJ, Baidoo EEK, Costello Z, Ando D, Alonso-Gutierrez J, George KW, Mukhopadhyay A, Vaino I, Keasling J, Adams PD, Hillson NJ, Garcia Martin H. The Experiment Data Depot: A Web-Based Software Tool for Biological Experimental Data Storage, Sharing, and Visualization. ACS Synth Biol. 2017 Sep 08. PMID: 28826210.
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      3. Shymansky CM, Wang G, Baidoo EEK, Gin J, Apel AR, Mukhopadhyay A, García Martín H, Keasling J. Flux-Enabled Exploration of the Role of Sip1 in Galactose Yeast Metabolism. Front Bioeng Biotechnol. 2017; 5:31. PMID: 28596955.
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      4. Mendez-Perez D, Alonso-Gutierrez J, Hu Q, Molinas M, Baidoo EEK, Wang G, Chan LJG, Adams PD, Petzold CJ, Keasling J, Lee TS. Production of jet fuel precursor monoterpenoids from engineered Escherichia coli. Biotechnol Bioeng. 2017 Aug; 114(8):1703-1712. PMID: 28369701.
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      5. de Raad M, de Rond T, Rübel O, Keasling J, Northen TR, Bowen BP. OpenMSI Arrayed Analysis Toolkit: Analyzing Spatially Defined Samples Using Mass Spectrometry Imaging. Anal Chem. 2017 Jun 06; 89(11):5818-5823. PMID: 28467051.
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      6. Parisutham V, Chandran SP, Mukhopadhyay A, Lee SK, Keasling J. Intracellular cellobiose metabolism and its applications in lignocellulose-based biorefineries. Bioresour Technol. 2017 Sep; 239:496-506. PMID: 28535986.
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      7. Zargar A, Bailey CB, Haushalter RW, Eiben CB, Katz L, Keasling J. Leveraging microbial biosynthetic pathways for the generation of 'drop-in' biofuels. Curr Opin Biotechnol. 2017 Jun; 45:156-163. PMID: 28427010.
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      8. Kang A, Meadows CW, Canu N, Keasling J, Lee TS. High-throughput enzyme screening platform for the IPP-bypass mevalonate pathway for isopentenol production. Metab Eng. 2017 May; 41:125-134. PMID: 28389395.
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      9. Haushalter RW, Phelan RM, Hoh KM, Su C, Wang G, Baidoo EE, Keasling J. Production of Odd-Carbon Dicarboxylic Acids in Escherichia coli Using an Engineered Biotin-Fatty Acid Biosynthetic Pathway. J Am Chem Soc. 2017 Apr 05; 139(13):4615-4618. PMID: 28291347.
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      10. Degreif D, de Rond T, Bertl A, Keasling J, Budin I. Lipid engineering reveals regulatory roles for membrane fluidity in yeast flocculation and oxygen-limited growth. Metab Eng. 2017 May; 41:46-56. PMID: 28323063.
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      11. Jensen ED, Ferreira R, Jakociunas T, Arsovska D, Zhang J, Ding L, Smith JD, David F, Nielsen J, Jensen MK, Keasling J. Transcriptional reprogramming in yeast using dCas9 and combinatorial gRNA strategies. Microb Cell Fact. 2017 Mar 15; 16(1):46. PMID: 28298224.
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      12. Liang Y, Richardson S, Yan J, Benites VT, Cheng-Yue C, Tran T, Mortimer J, Mukhopadhyay A, Keasling J, Scheller HV, Loqué D. Endoribonuclease-Based Two-Component Repressor Systems for Tight Gene Expression Control in Plants. ACS Synth Biol. 2017 May 19; 6(5):806-816. PMID: 28094975.
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      13. Chubukov V, Desmarais JJ, Wang G, Chan LJG, Baidoo EE, Petzold CJ, Keasling J, Mukhopadhyay A. Engineering glucose metabolism of Escherichia coli under nitrogen starvation. NPJ Syst Biol Appl. 2017; 3:16035. PMID: 28725483.
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      14. Zhang J, Barajas JF, Burdu M, Ruegg TL, Dias B, Keasling J. Development of a Transcription Factor-Based Lactam Biosensor. ACS Synth Biol. 2017 Mar 17; 6(3):439-445. PMID: 27997130.
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      15. He L, Xiu Y, Jones JA, Baidoo EE, Keasling J, Tang YJ, Koffas MA. Deciphering flux adjustments of engineered E. coli cells during fermentation with changing growth conditions. Metab Eng. 2017 Jan; 39:247-256. PMID: 28017690.
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      16. Reider Apel A, d'Espaux L, Wehrs M, Sachs D, Li RA, Tong GJ, Garber M, Nnadi O, Zhuang W, Hillson NJ, Keasling J, Mukhopadhyay A. A Cas9-based toolkit to program gene expression in Saccharomyces cerevisiae. Nucleic Acids Res. 2017 Jan 09; 45(1):496-508. PMID: 27899650.
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      17. Fang L, Ishikawa T, Rennie EA, Murawska GM, Lao J, Yan J, Tsai AY, Baidoo EE, Xu J, Keasling J, Demura T, Kawai-Yamada M, Scheller HV, Mortimer JC. Loss of Inositol Phosphorylceramide Sphingolipid Mannosylation Induces Plant Immune Responses and Reduces Cellulose Content in Arabidopsis. Plant Cell. 2016 Dec; 28(12):2991-3004. PMID: 27895225.
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      18. Eudes A, Mouille M, Robinson DS, Benites VT, Wang G, Roux L, Tsai YL, Baidoo EE, Chiu TY, Heazlewood JL, Scheller HV, Mukhopadhyay A, Keasling J, Deutsch S, Loqué D. Exploiting members of the BAHD acyltransferase family to synthesize multiple hydroxycinnamate and benzoate conjugates in yeast. Microb Cell Fact. 2016 Nov 21; 15(1):198. PMID: 27871334.
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      19. Yuzawa S, Keasling J, Katz L. Bio-based production of fuels and industrial chemicals by repurposing antibiotic-producing type I modular polyketide synthases: opportunities and challenges. J Antibiot (Tokyo). 2017 Apr; 70(4):378-385. PMID: 27847387.
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      20. Lechner A, Brunk E, Keasling J. The Need for Integrated Approaches in Metabolic Engineering. Cold Spring Harb Perspect Biol. 2016 Nov 01; 8(11). PMID: 27527588.
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      21. Kirby J, Dietzel KL, Wichmann G, Chan R, Antipov E, Moss N, Baidoo EE, Jackson P, Gaucher SP, Gottlieb S, LaBarge J, Mahatdejkul T, Hawkins KM, Muley S, Newman JD, Liu P, Keasling J, Zhao L. Engineering a functional 1-deoxy-D-xylulose 5-phosphate (DXP) pathway in Saccharomyces cerevisiae. Metab Eng. 2016 Oct 27. PMID: 27989805.
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      22. Hollinshead WD, Rodriguez S, Martin HG, Wang G, Baidoo EE, Sale KL, Keasling J, Mukhopadhyay A, Tang YJ. Examining Escherichia coli glycolytic pathways, catabolite repression, and metabolite channeling using ?pfk mutants. Biotechnol Biofuels. 2016; 9:212. PMID: 27766116.
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      23. Ghosh A, Ando D, Gin J, Runguphan W, Denby C, Wang G, Baidoo EE, Shymansky C, Keasling J, García Martín H. 13C Metabolic Flux Analysis for Systematic Metabolic Engineering of S. cerevisiae for Overproduction of Fatty Acids. Front Bioeng Biotechnol. 2016; 4:76. PMID: 27761435.
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      24. Phelan RM, Sachs D, Petkiewicz SJ, Barajas JF, Blake-Hedges JM, Thompson MG, Reider Apel A, Rasor BJ, Katz L, Keasling J. Development of Next Generation Synthetic Biology Tools for Use in Streptomyces venezuelae. ACS Synth Biol. 2017 01 20; 6(1):159-166. PMID: 27605473.
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      25. Skjoedt ML, Snoek T, Kildegaard KR, Arsovska D, Eichenberger M, Goedecke TJ, Rajkumar AS, Zhang J, Kristensen M, Lehka BJ, Siedler S, Borodina I, Jensen MK, Keasling J. Engineering prokaryotic transcriptional activators as metabolite biosensors in yeast. Nat Chem Biol. 2016 Nov; 12(11):951-958. PMID: 27642864.
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      26. Yuzawa S, Deng K, Wang G, Baidoo EE, Northen TR, Adams PD, Katz L, Keasling J. Comprehensive in Vitro Analysis of Acyltransferase Domain Exchanges in Modular Polyketide Synthases and Its Application for Short-Chain Ketone Production. ACS Synth Biol. 2017 01 20; 6(1):139-147. PMID: 27548700.
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      27. Zargar K, Saville R, Phelan RM, Tringe SG, Petzold CJ, Keasling J, Beller HR. In vitro Characterization of Phenylacetate Decarboxylase, a Novel Enzyme Catalyzing Toluene Biosynthesis in an Anaerobic Microbial Community. Sci Rep. 2016 Aug 10; 6:31362. PMID: 27506494; PMCID: PMC4979209.
      28. Brown ME, Mukhopadhyay A, Keasling J. Engineering Bacteria to Catabolize the Carbonaceous Component of Sarin: Teaching E. coli to Eat Isopropanol. ACS Synth Biol. 2016 12 16; 5(12):1485-1496. PMID: 27403844.
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      29. Zhang J, Sonnenschein N, Pihl TP, Pedersen KR, Jensen MK, Keasling J. Engineering an NADPH/NADP+ Redox Biosensor in Yeast. ACS Synth Biol. 2016 12 16; 5(12):1546-1556. PMID: 27419466.
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      30. Eudes A, Zhao N, Sathitsuksanoh N, Baidoo EE, Lao J, Wang G, Yogiswara S, Lee TS, Singh S, Mortimer JC, Keasling J, Simmons BA, Loqué D. Expression of S-adenosylmethionine Hydrolase in Tissues Synthesizing Secondary Cell Walls Alters Specific Methylated Cell Wall Fractions and Improves Biomass Digestibility. Front Bioeng Biotechnol. 2016; 4:58. PMID: 27486577; PMCID: PMC4949269.
      31. Jessop-Fabre MM, Jakociunas T, Stovicek V, Dai Z, Jensen MK, Keasling J, Borodina I. EasyClone-MarkerFree: A vector toolkit for marker-less integration of genes into Saccharomyces cerevisiae via CRISPR-Cas9. Biotechnol J. 2016 Aug; 11(8):1110-7. PMID: 27166612.
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      32. Rajkumar AS, Liu G, Bergenholm D, Arsovska D, Kristensen M, Nielsen J, Jensen MK, Keasling J. Engineering of synthetic, stress-responsive yeast promoters. Nucleic Acids Res. 2016 Sep 30; 44(17):e136. PMID: 27325743.
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      33. Yuzawa S, Keasling J, Katz L. Insights into polyketide biosynthesis gained from repurposing antibiotic-producing polyketide synthases to produce fuels and chemicals. J Antibiot (Tokyo). 2016 Jul; 69(7):494-9. PMID: 27245558.
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      34. Chubukov V, Mukhopadhyay A, Petzold CJ, Keasling J, Martín HG. Synthetic and systems biology for microbial production of commodity chemicals. NPJ Syst Biol Appl. 2016; 2:16009. PMID: 28725470.
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      35. Eng CH, Yuzawa S, Wang G, Baidoo EE, Katz L, Keasling J. Alteration of Polyketide Stereochemistry from anti to syn by a Ketoreductase Domain Exchange in a Type I Modular Polyketide Synthase Subunit. Biochemistry. 2016 Mar 29; 55(12):1677-80. PMID: 26976746.
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      36. Javidpour P, Deutsch S, Mutalik VK, Hillson NJ, Petzold CJ, Keasling J, Beller HR. Investigation of Proposed Ladderane Biosynthetic Genes from Anammox Bacteria by Heterologous Expression in E. coli. PLoS One. 2016; 11(3):e0151087. PMID: 26975050; PMCID: PMC4790861.
      37. Nielsen J, Keasling J. Engineering Cellular Metabolism. Cell. 2016 Mar 10; 164(6):1185-1197. PMID: 26967285.
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      38. Rodriguez S, Denby CM, Van Vu T, Baidoo EE, Wang G, Keasling J. ATP citrate lyase mediated cytosolic acetyl-CoA biosynthesis increases mevalonate production in Saccharomyces cerevisiae. Microb Cell Fact. 2016 Mar 03; 15:48. PMID: 26939608; PMCID: PMC4778282.
      39. Gach PC, Shih SC, Sustarich J, Keasling J, Hillson NJ, Adams PD, Singh AK. A Droplet Microfluidic Platform for Automating Genetic Engineering. ACS Synth Biol. 2016 May 20; 5(5):426-33. PMID: 26830031.
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      40. Hsia J, Holtz WJ, Maharbiz MM, Arcak M, Keasling J. Modular Synthetic Inverters from Zinc Finger Proteins and Small RNAs. PLoS One. 2016; 11(2):e0149483. PMID: 26886888; PMCID: PMC4757538.
      41. Eudes A, Pereira JH, Yogiswara S, Wang G, Teixeira Benites V, Baidoo EE, Lee TS, Adams PD, Keasling J, Loqué D. Exploiting the Substrate Promiscuity of Hydroxycinnamoyl-CoA:Shikimate Hydroxycinnamoyl Transferase to Reduce Lignin. Plant Cell Physiol. 2016 Mar; 57(3):568-79. PMID: 26858288; PMCID: PMC4790474.
      42. Linshiz G, Jensen E, Stawski N, Bi C, Elsbree N, Jiao H, Kim J, Mathies R, Keasling J, Hillson NJ. End-to-end automated microfluidic platform for synthetic biology: from design to functional analysis. J Biol Eng. 2016; 10:3. PMID: 26839585; PMCID: PMC4736182.
      43. Reider Apel A, Ouellet M, Szmidt-Middleton H, Keasling J, Mukhopadhyay A. Evolved hexose transporter enhances xylose uptake and glucose/xylose co-utilization in Saccharomyces cerevisiae. Sci Rep. 2016 Jan 19; 6:19512. PMID: 26781725; PMCID: PMC4726032.
      44. Foo JL, Susanto AV, Keasling J, Leong SS, Chang MW. Whole-cell biocatalytic and de novo production of alkanes from free fatty acids in Saccharomyces cerevisiae. Biotechnol Bioeng. 2017 Jan; 114(1):232-237. PMID: 26717118.
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      45. Kang A, George KW, Wang G, Baidoo E, Keasling J, Lee TS. Isopentenyl diphosphate (IPP)-bypass mevalonate pathways for isopentenol production. Metab Eng. 2016 Mar; 34:25-35. PMID: 26708516.
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      46. Jakociunas T, Jensen MK, Keasling J. CRISPR/Cas9 advances engineering of microbial cell factories. Metab Eng. 2016 Mar; 34:44-59. PMID: 26707540.
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      47. Hagen A, Poust S, Rond Td, Fortman JL, Katz L, Petzold CJ, Keasling J. Engineering a Polyketide Synthase for In Vitro Production of Adipic Acid. ACS Synth Biol. 2016 Jan 15; 5(1):21-7. PMID: 26501439.
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      48. d'Espaux L, Mendez-Perez D, Li R, Keasling J. Synthetic biology for microbial production of lipid-based biofuels. Curr Opin Chem Biol. 2015 Dec; 29:58-65. PMID: 26479184.
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      49. Eudes A, Teixeira Benites V, Wang G, Baidoo EE, Lee TS, Keasling J, Loqué D. Precursor-Directed Combinatorial Biosynthesis of Cinnamoyl, Dihydrocinnamoyl, and Benzoyl Anthranilates in Saccharomyces cerevisiae. PLoS One. 2015; 10(10):e0138972. PMID: 26430899; PMCID: PMC4591981.
      50. Martín HG, Kumar VS, Weaver D, Ghosh A, Chubukov V, Mukhopadhyay A, Arkin A, Keasling J. A Method to Constrain Genome-Scale Models with 13C Labeling Data. PLoS Comput Biol. 2015 Sep; 11(9):e1004363. PMID: 26379153; PMCID: PMC4574858.
      51. Barajas JF, Phelan RM, Schaub AJ, Kliewer JT, Kelly PJ, Jackson DR, Luo R, Keasling J, Tsai SC. Comprehensive Structural and Biochemical Analysis of the Terminal Myxalamid Reductase Domain for the Engineered Production of Primary Alcohols. Chem Biol. 2015 Aug 20; 22(8):1018-29. PMID: 26235055.
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      52. Ronda C, Maury J, Jakociunas T, Jacobsen SA, Germann SM, Harrison SJ, Borodina I, Keasling J, Jensen MK, Nielsen AT. CrEdit: CRISPR mediated multi-loci gene integration in Saccharomyces cerevisiae. Microb Cell Fact. 2015 Jul 07; 14:97. PMID: 26148499; PMCID: PMC4492099.
      53. Wenz C, Barbas C, López-Gonzálvez Á, Garcia A, Benavente F, Sanz-Nebot V, Blanc T, Freckleton G, Britz-McKibbin P, Shanmuganathan M, de l'Escaille F, Far J, Haselberg R, Huang S, Huhn C, Pattky M, Michels D, Mou S, Yang F, Neusuess C, Tromsdorf N, Baidoo EE, Keasling J, Park SS. Interlaboratory study to evaluate the robustness of capillary electrophoresis-mass spectrometry for peptide mapping. J Sep Sci. 2015 Jul 06. PMID: 26147246.
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      54. Johnson RE, de Rond T, Lindsay VN, Keasling J, Sarpong R. Synthesis of Cycloprodigiosin Identifies the Natural Isolate as a Scalemic Mixture. Org Lett. 2015 Jul 17; 17(14):3474-7. PMID: 26114660; PMCID: PMC4509414.
      55. Poust S, Piety J, Bar-Even A, Louw C, Baker D, Keasling J, Siegel JB. Mechanistic Analysis of an Engineered Enzyme that Catalyzes the Formose Reaction. Chembiochem. 2015 Jun 24. PMID: 26109266.
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      56. Shih SC, Goyal G, Kim PW, Koutsoubelis N, Keasling J, Adams PD, Hillson NJ, Singh AK. A Versatile Microfluidic Device for Automating Synthetic Biology. ACS Synth Biol. 2015 Oct 16; 4(10):1151-64. PMID: 26075958.
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      57. George KW, Thompson MG, Kang A, Baidoo E, Wang G, Chan LJ, Adams PD, Petzold CJ, Keasling J, Lee TS. Metabolic engineering for the high-yield production of isoprenoid-based C5 alcohols in E. coli. Sci Rep. 2015 Jun 08; 5:11128. PMID: 26052683; PMCID: PMC4459108.
      58. Zhang J, Jensen MK, Keasling J. Development of biosensors and their application in metabolic engineering. Curr Opin Chem Biol. 2015 Oct; 28:1-8. PMID: 26056948.
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      59. Chubukov V, Mingardon F, Schackwitz W, Baidoo EE, Alonso-Gutierrez J, Hu Q, Lee TS, Keasling J, Mukhopadhyay A. Acute Limonene Toxicity in Escherichia coli Is Caused by Limonene Hydroperoxide and Alleviated by a Point Mutation in Alkyl Hydroperoxidase AhpC. Appl Environ Microbiol. 2015 Jul; 81(14):4690-6. PMID: 25934627; PMCID: PMC4551201.
      60. Walley J, Xiao Y, Wang JZ, Baidoo EE, Keasling J, Shen Z, Briggs SP, Dehesh K. Plastid-produced interorgannellar stress signal MEcPP potentiates induction of the unfolded protein response in endoplasmic reticulum. Proc Natl Acad Sci U S A. 2015 May 12; 112(19):6212-7. PMID: 25922532; PMCID: PMC4434691.
      61. Haushalter RW, Groff D, Deutsch S, The L, Chavkin TA, Brunner SF, Katz L, Keasling J. Development of an orthogonal fatty acid biosynthesis system in E. coli for oleochemical production. Metab Eng. 2015 Jul; 30:1-6. PMID: 25887638.
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      62. Jakociunas T, Rajkumar AS, Zhang J, Arsovska D, Rodriguez A, Jendresen CB, Skjødt ML, Nielsen AT, Borodina I, Jensen MK, Keasling J. CasEMBLR: Cas9-Facilitated Multiloci Genomic Integration of in Vivo Assembled DNA Parts in Saccharomyces cerevisiae. ACS Synth Biol. 2015 Nov 20; 4(11):1226-34. PMID: 25781611.
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      63. Siegel JB, Smith AL, Poust S, Wargacki AJ, Bar-Even A, Louw C, Shen BW, Eiben CB, Tran HM, Noor E, Gallaher JL, Bale J, Yoshikuni Y, Gelb MH, Keasling J, Stoddard BL, Lidstrom ME, Baker D. Computational protein design enables a novel one-carbon assimilation pathway. Proc Natl Acad Sci U S A. 2015 Mar 24; 112(12):3704-9. PMID: 25775555; PMCID: PMC4378393.
      64. Jakociunas T, Bonde I, Herrgård M, Harrison SJ, Kristensen M, Pedersen LE, Jensen MK, Keasling J. Multiplex metabolic pathway engineering using CRISPR/Cas9 in Saccharomyces cerevisiae. Metab Eng. 2015 Mar; 28:213-22. PMID: 25638686.
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      65. Vega-Sánchez ME, Loqué D, Lao J, Catena M, Verhertbruggen Y, Herter T, Yang F, Harholt J, Ebert B, Baidoo EE, Keasling J, Scheller HV, Heazlewood JL, Ronald PC. Engineering temporal accumulation of a low recalcitrance polysaccharide leads to increased C6 sugar content in plant cell walls. Plant Biotechnol J. 2015 Sep; 13(7):903-14. PMID: 25586315.
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      66. Jensen MK, Keasling J. Recent applications of synthetic biology tools for yeast metabolic engineering. FEMS Yeast Res. 2015 Feb; 15(1):1-10. PMID: 25041737.
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      67. Eudes A, Sathitsuksanoh N, Baidoo EE, George A, Liang Y, Yang F, Singh S, Keasling J, Simmons BA, Loqué D. Expression of a bacterial 3-dehydroshikimate dehydratase reduces lignin content and improves biomass saccharification efficiency. Plant Biotechnol J. 2015 Dec; 13(9):1241-50. PMID: 25583257.
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      68. Poust S, Phelan RM, Deng K, Katz L, Petzold CJ, Keasling J. Divergent mechanistic routes for the formation of gem-dimethyl groups in the biosynthesis of complex polyketides. Angew Chem Int Ed Engl. 2015 Feb 16; 54(8):2370-3. PMID: 25564997.
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      69. George KW, Alonso-Gutierrez J, Keasling J, Lee TS. Erratum to: Isoprenoid Drugs, Biofuels, and Chemicals--Artemisinin, Farnesene, and Beyond. Adv Biochem Eng Biotechnol. 2015; 148:469. PMID: 25813866.
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      70. George KW, Alonso-Gutierrez J, Keasling J, Lee TS. Isoprenoid drugs, biofuels, and chemicals--artemisinin, farnesene, and beyond. Adv Biochem Eng Biotechnol. 2015; 148:355-89. PMID: 25577395.
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      71. Alonso-Gutierrez J, Kim EM, Batth TS, Cho N, Hu Q, Chan LJ, Petzold CJ, Hillson NJ, Adams PD, Keasling J, Garcia Martin H, Lee TS. Principal component analysis of proteomics (PCAP) as a tool to direct metabolic engineering. Metab Eng. 2015 Mar; 28:123-33. PMID: 25554074.
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      72. Foo JL, Jensen HM, Dahl RH, George K, Keasling J, Lee TS, Leong S, Mukhopadhyay A. Improving microbial biogasoline production in Escherichia coli using tolerance engineering. MBio. 2014 Nov 04; 5(6):e01932. PMID: 25370492; PMCID: PMC4222104.
      73. Kirby J, Nishimoto M, Chow RW, Baidoo EE, Wang G, Martin J, Schackwitz W, Chan R, Fortman JL, Keasling J. Enhancing Terpene yield from sugars via novel routes to 1-deoxy-d-xylulose 5-phosphate. Appl Environ Microbiol. 2015 Jan; 81(1):130-8. PMID: 25326299; PMCID: PMC4272731.
      74. Poust S, Yoon I, Adams PD, Katz L, Petzold CJ, Keasling J. Understanding the role of histidine in the GHSxG acyltransferase active site motif: evidence for histidine stabilization of the malonyl-enzyme intermediate. PLoS One. 2014; 9(10):e109421. PMID: 25286165; PMCID: PMC4186864.
      75. Scullin C, Stavila V, Skarstad A, Keasling J, Simmons BA, Singh S. Optimization of renewable pinene production from the conversion of macroalgae Saccharina latissima. Bioresour Technol. 2015 May; 184:415-20. PMID: 25318906.
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      76. Haushalter RW, Kim W, Chavkin TA, The L, Garber ME, Nhan M, Adams PD, Petzold CJ, Katz L, Keasling J. Production of anteiso-branched fatty acids in Escherichia coli; next generation biofuels with improved cold-flow properties. Metab Eng. 2014 Nov; 26:111-118. PMID: 25250846.
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      77. Goh EB, Baidoo EEK, Burd H, Lee TS, Keasling J, Beller HR. Substantial improvements in methyl ketone production in E. coli and insights on the pathway from in vitro studies. Metab Eng. 2014 Nov; 26:67-76. PMID: 25241399.
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      78. Hagen A, Poust S, de Rond T, Yuzawa S, Katz L, Adams PD, Petzold CJ, Keasling J. In vitro analysis of carboxyacyl substrate tolerance in the loading and first extension modules of borrelidin polyketide synthase. Biochemistry. 2014 Sep 30; 53(38):5975-7. PMID: 25188840.
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      79. Batth TS, Singh P, Ramakrishnan VR, Sousa MML, Chan LJG, Tran HM, Luning EG, Pan EHY, Vuu KM, Keasling J, Adams PD, Petzold CJ. A targeted proteomics toolkit for high-throughput absolute quantification of Escherichia coli proteins. Metab Eng. 2014 Nov; 26:48-56. PMID: 25205128.
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      80. Ghosh A, Nilmeier J, Weaver D, Adams PD, Keasling J, Mukhopadhyay A, Petzold CJ, Martín HG. A peptide-based method for 13C Metabolic Flux Analysis in microbial communities. PLoS Comput Biol. 2014 Sep; 10(9):e1003827. PMID: 25188426; PMCID: PMC4154649.
      81. Kirby J, Nishimoto M, Chow RW, Pasumarthi VN, Chan R, Chan LJ, Petzold CJ, Keasling J. Use of nonionic surfactants for improvement of terpene production in Saccharomyces cerevisiae. Appl Environ Microbiol. 2014 Nov; 80(21):6685-93. PMID: 25149518; PMCID: PMC4249056.
      82. Weaver LJ, Sousa MM, Wang G, Baidoo E, Petzold CJ, Keasling J. A kinetic-based approach to understanding heterologous mevalonate pathway function in E. coli. Biotechnol Bioeng. 2015 Jan; 112(1):111-9. PMID: 24981116.
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      268. Yoon SH, Lee YM, Kim JE, Lee SH, Lee JH, Kim JY, Jung KH, Shin YC, Keasling J, Kim SW. Enhanced lycopene production in Escherichia coli engineered to synthesize isopentenyl diphosphate and dimethylallyl diphosphate from mevalonate. Biotechnol Bioeng. 2006 Aug 20; 94(6):1025-32. PMID: 16547999.
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      272. Mukhopadhyay A, He Z, Alm EJ, Arkin AP, Baidoo EE, Borglin SC, Chen W, Hazen TC, He Q, Holman HY, Huang K, Huang R, Joyner DC, Katz N, Keller M, Oeller P, Redding A, Sun J, Wall J, Wei J, Yang Z, Yen HC, Zhou J, Keasling J. Salt stress in Desulfovibrio vulgaris Hildenborough: an integrated genomics approach. J Bacteriol. 2006 Jun; 188(11):4068-78. PMID: 16707698; PMCID: PMC1482918.
      273. Baker D, Church G, Collins J, Endy D, Jacobson J, Keasling J, Modrich P, Smolke C, Weiss R. Engineering life: building a fab for biology. Sci Am. 2006 Jun; 294(6):44-51. PMID: 16711359.
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      274. Redding AM, Mukhopadhyay A, Joyner DC, Hazen TC, Keasling J. Study of nitrate stress in Desulfovibrio vulgaris Hildenborough using iTRAQ proteomics. Brief Funct Genomic Proteomic. 2006 Jun; 5(2):133-43. PMID: 16772278.
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      275. Zahiri HS, Yoon SH, Keasling J, Lee SH, Won Kim S, Yoon SC, Shin YC. Coenzyme Q10 production in recombinant Escherichia coli strains engineered with a heterologous decaprenyl diphosphate synthase gene and foreign mevalonate pathway. Metab Eng. 2006 Sep; 8(5):406-16. PMID: 16815062.
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      278. Lee SK, Keasling J. A Salmonella-based, propionate-inducible, expression system for Salmonella enterica. Gene. 2006 Aug 01; 377:6-11. PMID: 16616438.
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      283. Yoshikuni Y, Martin VJ, Ferrin TE, Keasling J. Engineering cotton (+)-delta-cadinene synthase to an altered function: germacrene D-4-ol synthase. Chem Biol. 2006 Jan; 13(1):91-8. PMID: 16426975.
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      284. Pfleger BF, Fawzi NJ, Keasling J. Optimization of DsRed production in Escherichia coli: effect of ribosome binding site sequestration on translation efficiency. Biotechnol Bioeng. 2005 Dec 05; 92(5):553-8. PMID: 16247774.
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      286. Voigt CA, Keasling J. Programming cellular function. Nat Chem Biol. 2005 Nov; 1(6):304-7. PMID: 16408063.
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      290. da Costa BM, Keasling J, Cornish K. Regulation of rubber biosynthetic rate and molecular weight in Hevea brasiliensis by metal cofactor. Biomacromolecules. 2005 Jan-Feb; 6(1):279-89. PMID: 15638531.
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      291. Renninger N, Knopp R, Nitsche H, Clark DS, Keasling J. Uranyl precipitation by Pseudomonas aeruginosa via controlled polyphosphate metabolism. Appl Environ Microbiol. 2004 Dec; 70(12):7404-12. PMID: 15574942; PMCID: PMC535141.
      292. Reichmuth DS, Blanch HW, Keasling J. Dibenzothiophene biodesulfurization pathway improvement using diagnostic GFP fusions. Biotechnol Bioeng. 2004 Oct 05; 88(1):94-9. PMID: 15389482.
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      294. Maharbiz MM, Holtz WJ, Howe RT, Keasling J. Microbioreactor arrays with parametric control for high-throughput experimentation. Biotechnol Bioeng. 2004 May 20; 86(4):485-90. PMID: 15146839.
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      296. Khosla C, Keasling J. Metabolic engineering for drug discovery and development. Nat Rev Drug Discov. 2003 Dec; 2(12):1019-25. PMID: 14654799.
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      298. Aldor IS, Keasling J. Process design for microbial plastic factories: metabolic engineering of polyhydroxyalkanoates. Curr Opin Biotechnol. 2003 Oct; 14(5):475-83. PMID: 14580576.
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      324. Wang CL, Lum AM, Ozuna SC, Clark DS, Keasling J. Aerobic sulfide production and cadmium precipitation by Escherichia coli expressing the Treponema denticola cysteine desulfhydrase gene. Appl Microbiol Biotechnol. 2001 Aug; 56(3-4):425-30. PMID: 11549014.
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