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    Wemmer, David

    TitleChemist Senior Faculty
    SchoolLawrence Berkeley National Lab
    DepartmentMolecular Biophys & Integ Bio
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/666-2683
    vCardDownload vCard

      Collapse Bibliographic 
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Slack CC, Finbloom JA, Jeong K, Bruns CJ, Wemmer D, Pines A, Francis MB. Rotaxane probes for protease detection by 129Xe hyperCEST NMR. Chem Commun (Camb). 2017 Jan 17; 53(6):1076-1079. PMID: 28044166.
        View in: PubMed
      2. Siegel AR, Wemmer D. Role of the s54 Activator Interacting Domain in Bacterial Transcription Initiation. J Mol Biol. 2016 Nov 20; 428(23):4669-4685. PMID: 27732872.
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      3. Wemmer D. SnapShot: Biomolecular NMR. Cell. 2016 Sep 08; 166(6):1600. PMID: 27610579.
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      4. Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wright PE, Wemmer D. Solid-State NMR Studies Reveal Native-like ß-Sheet Structures in Transthyretin Amyloid. Biochemistry. 2016 Sep 20; 55(37):5272-8. PMID: 27589034; PMCID: PMC5035109.
      5. Jeong K, Netirojjanakul C, Munch HK, Sun J, Finbloom JA, Wemmer D, Pines A, Francis MB. Targeted Molecular Imaging of Cancer Cells Using MS2-Based (129)Xe NMR. Bioconjug Chem. 2016 Aug 17; 27(8):1796-801. PMID: 27454679.
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      6. Gomes MD, Dao P, Jeong K, Slack CC, Vassiliou CC, Finbloom JA, Francis MB, Wemmer D, Pines A. (129)Xe NMR Relaxation-Based Macromolecular Sensing. J Am Chem Soc. 2016 Aug 10; 138(31):9747-50. PMID: 27472048.
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      7. Bhowmick A, Brookes DH, Yost SR, Dyson HJ, Forman-Kay JD, Gunter D, Head-Gordon M, Hura GL, Pande VS, Wemmer D, Wright PE, Head-Gordon T. Finding Our Way in the Dark Proteome. J Am Chem Soc. 2016 Aug 10; 138(31):9730-42. PMID: 27387657.
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      8. Lim KH, Dasari AK, Hung I, Gan Z, Kelly JW, Wemmer D. Structural Changes Associated with Transthyretin Misfolding and Amyloid Formation Revealed by Solution and Solid-State NMR. Biochemistry. 2016 Apr 05; 55(13):1941-4. PMID: 26998642; PMCID: PMC4904294.
      9. Truxal AE, Slack CC, Gomes MD, Vassiliou CC, Wemmer D, Pines A. Nondisruptive Dissolution of Hyperpolarized (129)Xe into Viscous Aqueous and Organic Liquid Crystalline Environments. Angew Chem Int Ed Engl. 2016 Apr 04; 55(15):4666-70. PMID: 26954536.
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      10. Finbloom JA, Slack CC, Bruns CJ, Jeong K, Wemmer D, Pines A, Francis MB. Rotaxane-mediated suppression and activation of cucurbit[6]uril for molecular detection by (129)Xe hyperCEST NMR. Chem Commun (Camb). 2016 Feb 21; 52(15):3119-22. PMID: 26795714.
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      11. Xu H, Kim S, Sorek H, Lee Y, Jeong D, Kim J, Oh EJ, Yun EJ, Wemmer D, Kim KH, Kim SR, Jin YS. PHO13 deletion-induced transcriptional activation prevents sedoheptulose accumulation during xylose metabolism in engineered Saccharomyces cerevisiae. Metab Eng. 2016 Mar; 34:88-96. PMID: 26724864.
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      12. Sorek N, Szemenyei H, Sorek H, Landers A, Knight H, Bauer S, Wemmer D, Somerville CR. Identification of MEDIATOR16 as the Arabidopsis COBRA suppressor MONGOOSE1. Proc Natl Acad Sci U S A. 2015 Dec 29; 112(52):16048-53. PMID: 26655738; PMCID: PMC4703005.
      13. Jeong K, Slack CC, Vassiliou CC, Dao P, Gomes MD, Kennedy DJ, Truxal AE, Sperling LJ, Francis MB, Wemmer D, Pines A. Investigation of DOTA-Metal Chelation Effects on the Chemical Shift of (129) Xe. Chemphyschem. 2015 Dec 01; 16(17):3573-7. PMID: 26376768.
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      14. Sharma SC, Armand T, Ball KA, Chen A, Pelton JG, Wemmer D, Head-Gordon T. A facile method for expression and purification of (15)N isotope-labeled human Alzheimer's ß-amyloid peptides from E. coli for NMR-based structural analysis. Protein Expr Purif. 2015 Dec; 116:82-9. PMID: 26231074.
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      15. Hwang HJ, Min HJ, Yun H, Pelton JG, Wemmer D, Cho KO, Kim JS, Lee CW. Solution structure of the porcine sapovirus VPg core reveals a stable three-helical bundle with a conserved surface patch. Biochem Biophys Res Commun. 2015 Apr 17; 459(4):610-6. PMID: 25753201.
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      16. Sorek N, Sorek H, Kijac A, Szemenyei HJ, Bauer S, Hématy K, Wemmer D, Somerville CR. The Arabidopsis COBRA protein facilitates cellulose crystallization at the plasma membrane. J Biol Chem. 2014 Dec 12; 289(50):34911-20. PMID: 25331944; PMCID: PMC4263889.
      17. Vidangos NK, Heideker J, Lyubimov A, Lamers M, Huo Y, Pelton JG, Ton J, Gralla J, Berger J, Wemmer D. DNA recognition by a s(54) transcriptional activator from Aquifex aeolicus. J Mol Biol. 2014 Oct 23; 426(21):3553-68. PMID: 25158097; PMCID: PMC4188747.
      18. Ball KA, Wemmer D, Head-Gordon T. Comparison of structure determination methods for intrinsically disordered amyloid-ß peptides. J Phys Chem B. 2014 Jun 19; 118(24):6405-16. PMID: 24410358; PMCID: PMC4066902.
      19. De D, Jeong MH, Leem YE, Svergun DI, Wemmer D, Kang JS, Kim KK, Kim SH. Inhibition of master transcription factors in pluripotent cells induces early stage differentiation. Proc Natl Acad Sci U S A. 2014 Feb 04; 111(5):1778-83. PMID: 24434556; PMCID: PMC3918783.
      20. Garimella PD, Meldrum T, Witus LS, Smith M, Bajaj VS, Wemmer D, Francis MB, Pines A. Hyperpolarized xenon-based molecular sensors for label-free detection of analytes. J Am Chem Soc. 2014 Jan 08; 136(1):164-8. PMID: 24313335.
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      21. Vidangos N, Maris AE, Young A, Hong E, Pelton JG, Batchelor JD, Wemmer D. Structure, function, and tethering of DNA-binding domains in s54 transcriptional activators. Biopolymers. 2013 Dec; 99(12):1082-96. PMID: 23818155; PMCID: PMC3932985.
      22. Wan W, Bian W, McDonald M, Kijac A, Wemmer D, Stubbs G. Heterogeneous seeding of a prion structure by a generic amyloid form of the fungal prion-forming domain HET-s(218-289). J Biol Chem. 2013 Oct 11; 288(41):29604-12. PMID: 23986444; PMCID: PMC3795258.
      23. Iwig JS, Vercoulen Y, Das R, Barros T, Limnander A, Che Y, Pelton JG, Wemmer D, Roose JP, Kuriyan J. Structural analysis of autoinhibition in the Ras-specific exchange factor RasGRP1. Elife. 2013 Jul 30; 2:e00813. PMID: 23908768; PMCID: PMC3728621.
      24. Ball KA, Phillips AH, Wemmer D, Head-Gordon T. Differences in ß-strand populations of monomeric Aß40 and Aß42. Biophys J. 2013 Jun 18; 104(12):2714-24. PMID: 23790380; PMCID: PMC3686344.
      25. Palaniappan KK, Ramirez RM, Bajaj VS, Wemmer D, Pines A, Francis MB. Molecular imaging of cancer cells using a bacteriophage-based 129Xe NMR biosensor. Angew Chem Int Ed Engl. 2013 Apr 26; 52(18):4849-53. PMID: 23554263.
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      26. Cheng K, Sorek H, Zimmermann H, Wemmer D, Pauly M. Solution-state 2D NMR spectroscopy of plant cell walls enabled by a dimethylsulfoxide-d6/1-ethyl-3-methylimidazolium acetate solvent. Anal Chem. 2013 Mar 19; 85(6):3213-21. PMID: 23413964.
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      27. Endres NF, Das R, Smith AW, Arkhipov A, Kovacs E, Huang Y, Pelton JG, Shan Y, Shaw DE, Wemmer D, Groves JT, Kuriyan J. Conformational coupling across the plasma membrane in activation of the EGF receptor. Cell. 2013 Jan 31; 152(3):543-56. PMID: 23374349; PMCID: PMC3718647.
      28. Arkhipov A, Shan Y, Das R, Endres NF, Eastwood MP, Wemmer D, Kuriyan J, Shaw DE. Architecture and membrane interactions of the EGF receptor. Cell. 2013 Jan 31; 152(3):557-69. PMID: 23374350; PMCID: PMC3680629.
      29. Batchelor JD, Lee PS, Wang AC, Doucleff M, Wemmer D. Structural mechanism of GAF-regulated s(54) activators from Aquifex aeolicus. J Mol Biol. 2013 Jan 09; 425(1):156-70. PMID: 23123379; PMCID: PMC3544215.
      30. Bauer S, Sorek H, Mitchell VD, Ibáñez AB, Wemmer D. Characterization of Miscanthus giganteus lignin isolated by ethanol organosolv process under reflux condition. J Agric Food Chem. 2012 Aug 22; 60(33):8203-12. PMID: 22823333.
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      31. Stevens TK, Palaniappan KK, Ramirez RM, Francis MB, Wemmer D, Pines A. HyperCEST detection of a 129Xe-based contrast agent composed of cryptophane-A molecular cages on a bacteriophage scaffold. Magn Reson Med. 2013 May; 69(5):1245-52. PMID: 22791581.
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      32. Leonelli L, Pelton J, Schoeffler A, Dahlbeck D, Berger J, Wemmer D, Staskawicz B. Structural elucidation and functional characterization of the Hyaloperonospora arabidopsidis effector protein ATR13. PLoS Pathog. 2011 Dec; 7(12):e1002428. PMID: 22194684; PMCID: PMC3240608.
      33. Ball KA, Phillips AH, Nerenberg PS, Fawzi NL, Wemmer D, Head-Gordon T. Homogeneous and heterogeneous tertiary structure ensembles of amyloid-ß peptides. Biochemistry. 2011 Sep 06; 50(35):7612-28. PMID: 21797254; PMCID: PMC3474852.
      34. Meldrum T, Bajaj VS, Wemmer D, Pines A. Band-selective chemical exchange saturation transfer imaging with hyperpolarized xenon-based molecular sensors. J Magn Reson. 2011 Dec; 213(1):14-21. PMID: 21974996.
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      35. Michalak DJ, Xu S, Lowery TJ, Crawford CW, Ledbetter M, Bouchard LS, Wemmer D, Budker D, Pines A. Relaxivity of gadolinium complexes detected by atomic magnetometry. Magn Reson Med. 2011 Aug; 66(2):605-8. PMID: 21433067.
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      36. Wickliffe KE, Lorenz S, Wemmer D, Kuriyan J, Rape M. The mechanism of linkage-specific ubiquitin chain elongation by a single-subunit E2. Cell. 2011 Mar 04; 144(5):769-81. PMID: 21376237; PMCID: PMC3072108.
      37. Hernandez JA, Phillips AH, Erbil WK, Zhao D, Demuez M, Zeymer C, Pelton JG, Wemmer D, Rubio LM. A sterile alpha-motif domain in NafY targets apo-NifDK for iron-molybdenum cofactor delivery via a tethered domain. J Biol Chem. 2011 Feb 25; 286(8):6321-8. PMID: 21156797; PMCID: PMC3057858.
      38. Schilling F, Schröder L, Palaniappan KK, Zapf S, Wemmer D, Pines A. MRI thermometry based on encapsulated hyperpolarized xenon. Chemphyschem. 2010 Nov 15; 11(16):3529-33. PMID: 20821795.
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      39. Wetzler M, Wemmer D. Facile dimer synthesis for DNA-binding polyamide ligands. Org Lett. 2010 Aug 06; 12(15):3488-90. PMID: 20670013.
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      40. Damo SM, Phillips AH, Young AL, Li S, Woods VL, Wemmer D. Probing the conformation of a prion protein fibril with hydrogen exchange. J Biol Chem. 2010 Oct 15; 285(42):32303-11. PMID: 20679344; PMCID: PMC2952231.
      41. Meldrum T, Schröder L, Denger P, Wemmer D, Pines A. Xenon-based molecular sensors in lipid suspensions. J Magn Reson. 2010 Aug; 205(2):242-6. PMID: 20542715.
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      42. Meldrum T, Seim KL, Bajaj VS, Palaniappan KK, Wu W, Francis MB, Wemmer D, Pines A. A xenon-based molecular sensor assembled on an MS2 viral capsid scaffold. J Am Chem Soc. 2010 May 05; 132(17):5936-7. PMID: 20392049.
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      43. Kim KS, Pelton JG, Inwood WB, Andersen U, Kustu S, Wemmer D. The Rut pathway for pyrimidine degradation: novel chemistry and toxicity problems. J Bacteriol. 2010 Aug; 192(16):4089-102. PMID: 20400551; PMCID: PMC2916427.
      44. Sterling HJ, Batchelor JD, Wemmer D, Williams ER. Effects of buffer loading for electrospray ionization mass spectrometry of a noncovalent protein complex that requires high concentrations of essential salts. J Am Soc Mass Spectrom. 2010 Jun; 21(6):1045-9. PMID: 20226685; PMCID: PMC2893594.
      45. Erbil WK, Price MS, Wemmer D, Marletta MA. A structural basis for H-NOX signaling in Shewanella oneidensis by trapping a histidine kinase inhibitory conformation. Proc Natl Acad Sci U S A. 2009 Nov 24; 106(47):19753-60. PMID: 19918063; PMCID: PMC2785238.
      46. Batchelor JD, Sterling HJ, Hong E, Williams ER, Wemmer D. Receiver domains control the active-state stoichiometry of Aquifex aeolicus sigma54 activator NtrC4, as revealed by electrospray ionization mass spectrometry. J Mol Biol. 2009 Oct 30; 393(3):634-43. PMID: 19699748; PMCID: PMC2763505.
      47. Inwood WB, Hall JA, Kim KS, Demirkhanyan L, Wemmer D, Zgurskaya H, Kustu S. Epistatic effects of the protease/chaperone HflB on some damaged forms of the Escherichia coli ammonium channel AmtB. Genetics. 2009 Dec; 183(4):1327-40. PMID: 19596908; PMCID: PMC2787424.
      48. Jura N, Endres NF, Engel K, Deindl S, Das R, Lamers MH, Wemmer D, Zhang X, Kuriyan J. Mechanism for activation of the EGF receptor catalytic domain by the juxtamembrane segment. Cell. 2009 Jun 26; 137(7):1293-307. PMID: 19563760; PMCID: PMC2814540.
      49. Buhrlage SJ, Bates CA, Rowe SP, Minter AR, Brennan BB, Majmudar CY, Wemmer D, Al-Hashimi H, Mapp AK. Amphipathic small molecules mimic the binding mode and function of endogenous transcription factors. ACS Chem Biol. 2009 May 15; 4(5):335-44. PMID: 19348463; PMCID: PMC2744096.
      50. Hong E, Doucleff M, Wemmer D. Structure of the RNA polymerase core-binding domain of sigma(54) reveals a likely conformational fracture point. J Mol Biol. 2009 Jul 03; 390(1):70-82. PMID: 19426742; PMCID: PMC3195411.
      51. Ledbetter MP, Crawford CW, Pines A, Wemmer D, Knappe S, Kitching J, Budker D. Optical detection of NMR J-spectra at zero magnetic field. J Magn Reson. 2009 Jul; 199(1):25-9. PMID: 19406678.
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      52. Batchelor JD, Doucleff M, Lee CJ, Matsubara K, De Carlo S, Heideker J, Lamers MH, Pelton JG, Wemmer D. Structure and regulatory mechanism of Aquifex aeolicus NtrC4: variability and evolution in bacterial transcriptional regulation. J Mol Biol. 2008 Dec 31; 384(5):1058-75. PMID: 18955063.
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      53. Schröder L, Meldrum T, Smith M, Lowery TJ, Wemmer D, Pines A. Temperature response of 129Xe depolarization transfer and its application for ultrasensitive NMR detection. Phys Rev Lett. 2008 Jun 27; 100(25):257603. PMID: 18643704.
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      54. Fawzi NL, Phillips AH, Ruscio JZ, Doucleff M, Wemmer D, Head-Gordon T. Structure and dynamics of the Abeta(21-30) peptide from the interplay of NMR experiments and molecular simulations. J Am Chem Soc. 2008 May 14; 130(19):6145-58. PMID: 18412346; PMCID: PMC3474854.
      55. Baxter NJ, Blackburn GM, Marston JP, Hounslow AM, Cliff MJ, Bermel W, Williams NH, Hollfelder F, Wemmer D, Waltho JP. Anionic charge is prioritized over geometry in aluminum and magnesium fluoride transition state analogs of phosphoryl transfer enzymes. J Am Chem Soc. 2008 Mar 26; 130(12):3952-8. PMID: 18318536.
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      56. Schröder L, Chavez L, Meldrum T, Smith M, Lowery TJ, Wemmer D, Pines A. Temperature-controlled molecular depolarization gates in nuclear magnetic resonance. Angew Chem Int Ed Engl. 2008; 47(23):4316-20. PMID: 18461575.
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      57. Matsuda S, Fillo JD, Henry AA, Rai P, Wilkens SJ, Dwyer TJ, Geierstanger BH, Wemmer D, Schultz PG, Spraggon G, Romesberg FE. Efforts toward expansion of the genetic alphabet: structure and replication of unnatural base pairs. J Am Chem Soc. 2007 Aug 29; 129(34):10466-73. PMID: 17685517; PMCID: PMC2536688.
      58. Lowery TJ, Pelton JG, Chandonia JM, Kim R, Yokota H, Wemmer D. NMR structure of the N-terminal domain of the replication initiator protein DnaA. J Struct Funct Genomics. 2007 Mar; 8(1):11-7. PMID: 17680349.
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      59. Fraser JS, Merlie JP, Echols N, Weisfield SR, Mignot T, Wemmer D, Zusman DR, Alber T. An atypical receiver domain controls the dynamic polar localization of the Myxococcus xanthus social motility protein FrzS. Mol Microbiol. 2007 Jul; 65(2):319-32. PMID: 17573816; PMCID: PMC1974792.
      60. Doucleff M, Pelton JG, Lee PS, Nixon BT, Wemmer D. Structural basis of DNA recognition by the alternative sigma-factor, sigma54. J Mol Biol. 2007 Jun 15; 369(4):1070-8. PMID: 17481658; PMCID: PMC2680387.
      61. Chen B, Doucleff M, Wemmer D, De Carlo S, Huang HH, Nogales E, Hoover TR, Kondrashkina E, Guo L, Nixon BT. ATP ground- and transition states of bacterial enhancer binding AAA+ ATPases support complex formation with their target protein, sigma54. Structure. 2007 Apr; 15(4):429-40. PMID: 17437715; PMCID: PMC2680074.
      62. Simon MD, Feldman ME, Rauh D, Maris AE, Wemmer D, Shokat KM. Structure and properties of a re-engineered homeodomain protein-DNA interface. ACS Chem Biol. 2006 Dec 15; 1(12):755-60. PMID: 17240973.
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      63. Tang YJ, Hwang JS, Wemmer D, Keasling JD. Shewanella oneidensis MR-1 fluxome under various oxygen conditions. Appl Environ Microbiol. 2007 Feb; 73(3):718-29. PMID: 17098921; PMCID: PMC1800752.
      64. Schröder L, Lowery TJ, Hilty C, Wemmer D, Pines A. Molecular imaging using a targeted magnetic resonance hyperpolarized biosensor. Science. 2006 Oct 20; 314(5798):446-9. PMID: 17053143.
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      65. Garcia S, Chavez L, Lowery TJ, Han SI, Wemmer D, Pines A. Sensitivity enhancement by exchange mediated magnetization transfer of the xenon biosensor signal. J Magn Reson. 2007 Jan; 184(1):72-7. PMID: 17046295.
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      66. Roberts A, Pelton JG, Wemmer D. Structural studies of MJ1529, an O6-methylguanine-DNA methyltransferase. Magn Reson Chem. 2006 Jul; 44 Spec No:S71-82. PMID: 16826543.
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      67. Pirruccello M, Sondermann H, Pelton JG, Pellicena P, Hoelz A, Chernoff J, Wemmer D, Kuriyan J. A dimeric kinase assembly underlying autophosphorylation in the p21 activated kinases. J Mol Biol. 2006 Aug 11; 361(2):312-26. PMID: 16837009.
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      68. Mynar JL, Lowery TJ, Wemmer D, Pines A, Fréchet JM. Xenon biosensor amplification via dendrimer-cage supramolecular constructs. J Am Chem Soc. 2006 May 17; 128(19):6334-5. PMID: 16683795.
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      69. Lowery TJ, Garcia S, Chavez L, Ruiz EJ, Wu T, Brotin T, Dutasta JP, King DS, Schultz PG, Pines A, Wemmer D. Optimization of xenon biosensors for detection of protein interactions. Chembiochem. 2006 Jan; 7(1):65-73. PMID: 16342304.
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      70. Hilty C, Lowery TJ, Wemmer D, Pines A. Spectrally resolved magnetic resonance imaging of a xenon biosensor. Angew Chem Int Ed Engl. 2005 Dec 16; 45(1):70-3. PMID: 16311999.
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      71. Wemmer D, Kern D. Rebuttal: conformational changes of Spo0F along the phosphotransfer pathway. J Bacteriol. 2005 Dec; 187(24):8228. PMID: 16321924; PMCID: PMC1317015.
      72. Wemmer D, Kern D. Beryllofluoride binding mimics phosphorylation of aspartate in response regulators. J Bacteriol. 2005 Dec; 187(24):8229-30. PMID: 16321925; PMCID: PMC1316999.
      73. Pelton JG, Shi J, Yokota H, Kim R, Wemmer D. NMR structure of hypothetical protein MG354 from Mycoplasma genitalium. Proteins. 2005 Nov 15; 61(3):666-8. PMID: 16184596.
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      74. Lim KH, Nguyen TN, Damo SM, Mazur T, Ball HL, Prusiner SB, Pines A, Wemmer D. Solid-state NMR structural studies of the fibril form of a mutant mouse prion peptide PrP89-143(P101L). Solid State Nucl Magn Reson. 2006 Feb; 29(1-3):183-90. PMID: 16256316.
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      75. Nixon BT, Yennawar HP, Doucleff M, Pelton JG, Wemmer D, Krueger S, Kondrashkina E. SAS solution structures of the apo and Mg2+/BeF3(-)-bound receiver domain of DctD from Sinorhizobium meliloti. Biochemistry. 2005 Oct 25; 44(42):13962-9. PMID: 16229485.
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      76. Doucleff M, Chen B, Maris AE, Wemmer D, Kondrashkina E, Nixon BT. Negative regulation of AAA + ATPase assembly by two component receiver domains: a transcription activation mechanism that is conserved in mesophilic and extremely hyperthermophilic bacteria. J Mol Biol. 2005 Oct 21; 353(2):242-55. PMID: 16169010.
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      77. Doucleff M, Malak LT, Pelton JG, Wemmer D. The C-terminal RpoN domain of sigma54 forms an unpredicted helix-turn-helix motif similar to domains of sigma70. J Biol Chem. 2005 Dec 16; 280(50):41530-6. PMID: 16210314.
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      78. Kim HS, Damo SM, Lee SY, Wemmer D, Klinman JP. Structure and hydride transfer mechanism of a moderate thermophilic dihydrofolate reductase from Bacillus stearothermophilus and comparison to its mesophilic and hyperthermophilic homologues. Biochemistry. 2005 Aug 30; 44(34):11428-39. PMID: 16114879.
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      79. Han SI, Garcia S, Lowery TJ, Ruiz EJ, Seeley JA, Chavez L, King DS, Wemmer D, Pines A. NMR-based biosensing with optimized delivery of polarized 129Xe to solutions. Anal Chem. 2005 Jul 01; 77(13):4008-12. PMID: 15987104.
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      80. Choi YJ, Ryu KS, Ko YM, Chae YK, Pelton JG, Wemmer D, Choi BS. Biophysical characterization of the interaction domains and mapping of the contact residues in the XPF-ERCC1 complex. J Biol Chem. 2005 Aug 05; 280(31):28644-52. PMID: 15932882.
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      81. Roberts A, Lee SY, McCullagh E, Silversmith RE, Wemmer D. YbiV from Escherichia coli K12 is a HAD phosphatase. Proteins. 2005 Mar 01; 58(4):790-801. PMID: 15657928.
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      82. Lowery TJ, Doucleff M, Ruiz EJ, Rubin SM, Pines A, Wemmer D. Distinguishing multiple chemotaxis Y protein conformations with laser-polarized 129Xe NMR. Protein Sci. 2005 Apr; 14(4):848-55. PMID: 15741343; PMCID: PMC2253452.
      83. Rai P, Wemmer D, Linn S. Preferential binding and structural distortion by Fe2+ at RGGG-containing DNA sequences correlates with enhanced oxidative cleavage at such sequences. Nucleic Acids Res. 2005; 33(2):497-510. PMID: 15659581; PMCID: PMC548341.
      84. Lowery TJ, Rubin SM, Ruiz EJ, Pines A, Wemmer D. Design of a conformation-sensitive xenon-binding cavity in the ribose-binding protein. Angew Chem Int Ed Engl. 2004 Nov 26; 43(46):6320-2. PMID: 15476190.
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      85. Spence MM, Ruiz EJ, Rubin SM, Lowery TJ, Winssinger N, Schultz PG, Wemmer D, Pines A. Development of a functionalized xenon biosensor. J Am Chem Soc. 2004 Nov 24; 126(46):15287-94. PMID: 15548026.
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      86. Zhang Q, Dwyer TJ, Tsui V, Case DA, Cho J, Dervan PB, Wemmer D. NMR structure of a cyclic polyamide-DNA complex. J Am Chem Soc. 2004 Jun 30; 126(25):7958-66. PMID: 15212545.
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      87. Shi J, Pelton JG, Cho HS, Wemmer D. Protein signal assignments using specific labeling and cell-free synthesis. J Biomol NMR. 2004 Mar; 28(3):235-47. PMID: 14752257.
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      88. Lowery TJ, Rubin SM, Ruiz EJ, Spence MM, Winssinger N, Schultz PG, Pines A, Wemmer D. Applications of laser-polarized 129Xe to biomolecular assays. Magn Reson Imaging. 2003 Dec; 21(10):1235-9. PMID: 14725931.
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      89. Wemmer D. The energetics of structural change in maltose-binding protein. Proc Natl Acad Sci U S A. 2003 Oct 28; 100(22):12529-30. PMID: 14569013; PMCID: PMC240646.
      90. Lee SY, De La Torre A, Yan D, Kustu S, Nixon BT, Wemmer D. Regulation of the transcriptional activator NtrC1: structural studies of the regulatory and AAA+ ATPase domains. Genes Dev. 2003 Oct 15; 17(20):2552-63. PMID: 14561776; PMCID: PMC218149.
      91. Nguyen TN, Wemmer D. Complete resonance assignments for the nudix hydrolase DR2356 of Deinococcus radiodurans. J Biomol NMR. 2003 Oct; 27(2):181-2. PMID: 12913415.
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      92. Hastings CA, Lee SY, Cho HS, Yan D, Kustu S, Wemmer D. High-resolution solution structure of the beryllofluoride-activated NtrC receiver domain. Biochemistry. 2003 Aug 05; 42(30):9081-90. PMID: 12885241.
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      93. Gardino AK, Volkman BF, Cho HS, Lee SY, Wemmer D, Kern D. The NMR solution structure of BeF(3)(-)-activated Spo0F reveals the conformational switch in a phosphorelay system. J Mol Biol. 2003 Aug 01; 331(1):245-54. PMID: 12875849.
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      94. Shin DH, Roberts A, Jancarik J, Yokota H, Kim R, Wemmer D, Kim SH. Crystal structure of a phosphatase with a unique substrate binding domain from Thermotoga maritima. Protein Sci. 2003 Jul; 12(7):1464-72. PMID: 12824492; PMCID: PMC2323937.
      95. Rubin SM, Pelton JG, Yokota H, Kim R, Wemmer D. Solution structure of a putative ribosome binding protein from Mycoplasma pneumoniae and comparison to a distant homolog. J Struct Funct Genomics. 2003; 4(4):235-43. PMID: 15185964.
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      97. Rubin SM, Lee SY, Ruiz EJ, Pines A, Wemmer D. Detection and characterization of xenon-binding sites in proteins by 129Xe NMR spectroscopy. J Mol Biol. 2002 Sep 13; 322(2):425-40. PMID: 12217701.
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      98. Liu K, Kelly JW, Wemmer D. Native state hydrogen exchange study of suppressor and pathogenic variants of transthyretin. J Mol Biol. 2002 Jul 19; 320(4):821-32. PMID: 12095258.
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      99. Lim KH, Nguyen T, Mazur T, Wemmer D, Pines A. Sensitivity enhancement in multiple-quantum NMR experiments with CPMG detection. J Magn Reson. 2002 Jul; 157(1):160-2. PMID: 12202146.
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      100. Supekova L, Pezacki JP, Su AI, Loweth CJ, Riedl R, Geierstanger B, Schultz PG, Wemmer D. Genomic effects of polyamide/DNA interactions on mRNA expression. Chem Biol. 2002 Jul; 9(7):821-7. PMID: 12144926.
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      101. Wang W, Cho HS, Kim R, Jancarik J, Yokota H, Nguyen HH, Grigoriev IV, Wemmer D, Kim SH. Structural characterization of the reaction pathway in phosphoserine phosphatase: crystallographic "snapshots" of intermediate states. J Mol Biol. 2002 May 31; 319(2):421-31. PMID: 12051918.
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      102. Westler WM, Frey PA, Lin J, Wemmer D, Morimoto H, Williams PG, Markley JL. Evidence for a strong hydrogen bond in the catalytic dyad of transition-state analogue inhibitor complexes of chymotrypsin from proton-triton NMR isotope shifts. J Am Chem Soc. 2002 Apr 24; 124(16):4196-7. PMID: 11960433.
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      103. Cho HS, Pelton JG, Yan D, Kustu S, Wemmer D. Phosphoaspartates in bacterial signal transduction. Curr Opin Struct Biol. 2001 Dec; 11(6):679-84. PMID: 11751048.
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      104. Havlin RH, Laws DD, Bitter HM, Sanders LK, Sun H, Grimley JS, Wemmer D, Pines A, Oldfield E. An experimental and theoretical investigation of the chemical shielding tensors of (13)C(alpha) of alanine, valine, and leucine residues in solid peptides and in proteins in solution. J Am Chem Soc. 2001 Oct 24; 123(42):10362-9. PMID: 11603987.
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      105. Rai P, Cole TD, Wemmer D, Linn S. Localization of Fe(2+) at an RTGR sequence within a DNA duplex explains preferential cleavage by Fe(2+) and H2O2. J Mol Biol. 2001 Oct 05; 312(5):1089-101. PMID: 11580252.
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      106. Laws DD, Bitter HM, Liu K, Ball HL, Kaneko K, Wille H, Cohen FE, Prusiner SB, Pines A, Wemmer D. Solid-state NMR studies of the secondary structure of a mutant prion protein fragment of 55 residues that induces neurodegeneration. Proc Natl Acad Sci U S A. 2001 Sep 25; 98(20):11686-90. PMID: 11562491; PMCID: PMC58790.
      107. Rubin SM, Spence MM, Dimitrov IE, Ruiz EJ, Pines A, Wemmer D. Detection of a conformational change in maltose binding protein by (129)Xe NMR spectroscopy. J Am Chem Soc. 2001 Sep 05; 123(35):8616-7. PMID: 11525678.
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      108. Spence MM, Rubin SM, Dimitrov IE, Ruiz EJ, Wemmer D, Pines A, Yao SQ, Tian F, Schultz PG. Functionalized xenon as a biosensor. Proc Natl Acad Sci U S A. 2001 Sep 11; 98(19):10654-7. PMID: 11535830; PMCID: PMC58521.
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      110. Cho H, Wang W, Kim R, Yokota H, Damo S, Kim SH, Wemmer D, Kustu S, Yan D. BeF(3)(-) acts as a phosphate analog in proteins phosphorylated on aspartate: structure of a BeF(3)(-) complex with phosphoserine phosphatase. Proc Natl Acad Sci U S A. 2001 Jul 17; 98(15):8525-30. PMID: 11438683; PMCID: PMC37469.
      111. Zhang Q, Harada K, Cho HS, Frankel AD, Wemmer D. Structural characterization of the complex of the Rev response element RNA with a selected peptide. Chem Biol. 2001 May; 8(5):511-20. PMID: 11358697.
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      112. Volkman BF, Lipson D, Wemmer D, Kern D. Two-state allosteric behavior in a single-domain signaling protein. Science. 2001 Mar 23; 291(5512):2429-33. PMID: 11264542.
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      113. Bastos M, Pease JH, Wemmer D, Murphy KP, Connelly PR. Thermodynamics of the helix-coil transition: Binding of S15 and a hybrid sequence, disulfide stabilized peptide to the S-protein. Proteins. 2001 Mar 01; 42(4):523-30. PMID: 11170206.
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      114. Hawkins CA, Watson C, Yan Y, Gong B, Wemmer D. Structural analysis of the binding modes of minor groove ligands comprised of disubstituted benzenes. Nucleic Acids Res. 2001 Feb 15; 29(4):936-42. PMID: 11160926; PMCID: PMC29609.
      115. Lee SY, Cho HS, Pelton JG, Yan D, Berry EA, Wemmer D. Crystal structure of activated CheY. Comparison with other activated receiver domains. J Biol Chem. 2001 May 11; 276(19):16425-31. PMID: 11279165.
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      116. Cave JW, Cho HS, Batchelder AM, Yokota H, Kim R, Wemmer D. Solution nuclear magnetic resonance structure of a protein disulfide oxidoreductase from Methanococcus jannaschii. Protein Sci. 2001 Feb; 10(2):384-96. PMID: 11266624; PMCID: PMC2373935.
      117. Lee SY, Cho HS, Pelton JG, Yan D, Henderson RK, King DS, Huang L, Kustu S, Berry EA, Wemmer D. Crystal structure of an activated response regulator bound to its target. Nat Struct Biol. 2001 Jan; 8(1):52-6. PMID: 11135671.
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      118. Rogers JP, Luginbühl P, Pemberton K, Harty P, Wemmer D, Stevens RC. Structure-activity relationships in a peptidic alpha7 nicotinic acetylcholine receptor antagonist. J Mol Biol. 2000 Dec 15; 304(5):911-26. PMID: 11124036.
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      119. Cave JW, Kremer W, Wemmer D. Backbone dynamics of sequence specific recognition and binding by the yeast Pho4 bHLH domain probed by NMR. Protein Sci. 2000 Dec; 9(12):2354-65. PMID: 11206057; PMCID: PMC2144533.
      120. Liu K, Cho HS, Hoyt DW, Nguyen TN, Olds P, Kelly JW, Wemmer D. Deuterium-proton exchange on the native wild-type transthyretin tetramer identifies the stable core of the individual subunits and indicates mobility at the subunit interface. J Mol Biol. 2000 Nov 03; 303(4):555-65. PMID: 11054291.
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      121. Liu K, Cho HS, Lashuel HA, Kelly JW, Wemmer D. A glimpse of a possible amyloidogenic intermediate of transthyretin. Nat Struct Biol. 2000 Sep; 7(9):754-7. PMID: 10966644.
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      122. Rubin SM, Spence MM, Goodson BM, Wemmer D, Pines A. Evidence of nonspecific surface interactions between laser-polarized xenon and myoglobin in solution. Proc Natl Acad Sci U S A. 2000 Aug 15; 97(17):9472-5. PMID: 10931956; PMCID: PMC16888.
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      124. Keating KA, Myers JD, Pelton JG, Bair RA, Wemmer D, Ellis PD. Development and use of a virtual NMR facility. J Magn Reson. 2000 Mar; 143(1):172-83. PMID: 10698658.
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      125. Robertson SA, Harada K, Frankel AD, Wemmer D. Structure determination and binding kinetics of a DNA aptamer-argininamide complex. Biochemistry. 2000 Feb 08; 39(5):946-54. PMID: 10653638.
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      126. Wemmer D. Designed sequence-specific minor groove ligands. Annu Rev Biophys Biomol Struct. 2000; 29:439-61. PMID: 10940255.
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      127. Yan D, Cho HS, Hastings CA, Igo MM, Lee SY, Pelton JG, Stewart V, Wemmer D, Kustu S. Beryllofluoride mimics phosphorylation of NtrC and other bacterial response regulators. Proc Natl Acad Sci U S A. 1999 Dec 21; 96(26):14789-94. PMID: 10611291; PMCID: PMC24726.
      128. Kern D, Volkman BF, Luginbühl P, Nohaile MJ, Kustu S, Wemmer D. Structure of a transiently phosphorylated switch in bacterial signal transduction. Nature. 1999 Dec 23-30; 402(6764):894-8. PMID: 10622255.
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      129. Pelton JG, Kustu S, Wemmer D. Solution structure of the DNA-binding domain of NtrC with three alanine substitutions. J Mol Biol. 1999 Oct 08; 292(5):1095-110. PMID: 10512705.
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      130. Cho CY, Liu CW, Wemmer D, Schultz PG. Cyclic and linear oligocarbamate ligands for human thrombin. Bioorg Med Chem. 1999 Jun; 7(6):1171-9. PMID: 10428389.
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      131. Rogers JP, Luginbühl P, Shen GS, McCabe RT, Stevens RC, Wemmer D. NMR solution structure of alpha-conotoxin ImI and comparison to other conotoxins specific for neuronal nicotinic acetylcholine receptors. Biochemistry. 1999 Mar 30; 38(13):3874-82. PMID: 10194298.
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      132. Peteranderl R, Rabenstein M, Shin YK, Liu CW, Wemmer D, King DS, Nelson HC. Biochemical and biophysical characterization of the trimerization domain from the heat shock transcription factor. Biochemistry. 1999 Mar 23; 38(12):3559-69. PMID: 10090742.
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      133. Wemmer D. Solid-state nuclear magnetic resonance of protein deposits. Methods Enzymol. 1999; 309:536-59. PMID: 10507047.
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      135. Wemmer D. The rational design of sequence-specific DNA minor groove binders using a 2:1 motif. Curr Opin Drug Discov Devel. 1998 Sep; 1(2):200-7. PMID: 19649820.
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      136. Wemmer D. Reading DNA. Nat Struct Biol. 1998 Mar; 5(3):169-71. PMID: 9501903.
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      137. Gehring K, Zhang X, Hall J, Nikaido H, Wemmer D. An NMR study of ligand binding by maltodextrin binding protein. Biochem Cell Biol. 1998; 76(2-3):189-97. PMID: 9923688.
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      138. Lee AL, Volkman BF, Robertson SA, Rudner DZ, Barbash DA, Cline TW, Kanaar R, Rio DC, Wemmer D. Chemical shift mapping of the RNA-binding interface of the multiple-RBD protein sex-lethal. Biochemistry. 1997 Nov 25; 36(47):14306-17. PMID: 9398148.
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      139. Nohaile M, Kern D, Wemmer D, Stedman K, Kustu S. Structural and functional analyses of activating amino acid substitutions in the receiver domain of NtrC: evidence for an activating surface. J Mol Biol. 1997 Oct 17; 273(1):299-316. PMID: 9367763.
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      140. Wemmer D, Dervan PB. Targeting the minor groove of DNA. Curr Opin Struct Biol. 1997 Jun; 7(3):355-61. PMID: 9204277.
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      141. Volkman BF, Wemmer D. Deletion of a single amino acid changes the folding of an apamin hybrid sequence peptide to that of endothelin. Biopolymers. 1997 Apr 05; 41(4):451-60. PMID: 9080780.
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      142. Heller J, Kolbert AC, Larsen R, Ernst M, Bekker T, Baldwin M, Prusiner SB, Pines A, Wemmer D. Solid-state NMR studies of the prion protein H1 fragment. Protein Sci. 1996 Aug; 5(8):1655-61. PMID: 8844854; PMCID: PMC2143492.
      143. Kubinec MG, Culf AS, Cho H, Lee DC, Burkham J, Morimoto H, Williams PG, Wemmer D. Applications of tritium NMR to macromolecules: a study of two nucleic acid molecules. J Biomol NMR. 1996 May; 7(3):236-46. PMID: 8785499.
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      144. Fagan PA, Spielmann HP, Sigurdsson S, Rink SM, Hopkins PB, Wemmer D. An NMR study of [d(CGCGAATTCGCG)]2 containing an interstrand cross-link derived from a distamycin-pyrrole conjugate. Nucleic Acids Res. 1996 Apr 15; 24(8):1566-73. PMID: 8628693; PMCID: PMC145811.
      145. Fagan PA, Fàbrega C, Eritja R, Goodman MF, Wemmer D. NMR study of the conformation of the 2-aminopurine:cytosine mismatch in DNA. Biochemistry. 1996 Apr 02; 35(13):4026-33. PMID: 8672436.
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      146. Geierstanger BH, Mrksich M, Dervan PB, Wemmer D. Extending the recognition site of designed minor groove binding molecules. Nat Struct Biol. 1996 Apr; 3(4):321-4. PMID: 8599756.
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      147. Cho HS, Liu CW, Damberger FF, Pelton JG, Nelson HC, Wemmer D. Yeast heat shock transcription factor N-terminal activation domains are unstructured as probed by heteronuclear NMR spectroscopy. Protein Sci. 1996 Feb; 5(2):262-9. PMID: 8745404; PMCID: PMC2143352.
      148. Wemmer D. New features in RNA recognition: a Tat-TAR complex. Chem Biol. 1996 Jan; 3(1):17-9. PMID: 8807823.
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      149. Damberger FF, Pelton JG, Liu C, Cho H, Harrison CJ, Nelson HC, Wemmer D. Refined solution structure and dynamics of the DNA-binding domain of the heat shock factor from Kluyveromyces lactis. J Mol Biol. 1995 Dec 08; 254(4):704-19. PMID: 7500344.
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      150. Liu H, Spielmann HP, Ulyanov NB, Wemmer D, James TL. Interproton distance bounds from 2D NOE intensities: effect of experimental noise and peak integration errors. J Biomol NMR. 1995 Dec; 6(4):390-402. PMID: 8563467.
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      151. Spielmann HP, Dwyer TJ, Hearst JE, Wemmer D. Solution structures of psoralen monoadducted and cross-linked DNA oligomers by NMR spectroscopy and restrained molecular dynamics. Biochemistry. 1995 Oct 10; 34(40):12937-53. PMID: 7548052.
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      152. Kanaar R, Lee AL, Rudner DZ, Wemmer D, Rio DC. Interaction of the sex-lethal RNA binding domains with RNA. EMBO J. 1995 Sep 15; 14(18):4530-9. PMID: 7556096; PMCID: PMC394545.
      153. Spielmann HP, Wemmer D, Jacobsen JP. Solution structure of a DNA complex with the fluorescent bis-intercalator TOTO determined by NMR spectroscopy. Biochemistry. 1995 Jul 11; 34(27):8542-53. PMID: 7612596.
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      154. Spielmann HP, Fagan PA, Bregant TM, Little RD, Wemmer D. The binding modes of a rationally designed photoactivated DNA nuclease determined by NMR. Nucleic Acids Res. 1995 May 11; 23(9):1576-83. PMID: 7784213; PMCID: PMC306900.
      155. Spielmann HP, Dwyer TJ, Sastry SS, Hearst JE, Wemmer D. DNA structural reorganization upon conversion of a psoralen furan-side monoadduct to an interstrand cross-link: implications for DNA repair. Proc Natl Acad Sci U S A. 1995 Mar 14; 92(6):2345-9. PMID: 7892269; PMCID: PMC42480.
      156. Jacobsen JP, Pedersen JB, Hansen LF, Wemmer D. Site selective bis-intercalation of a homodimeric thiazole orange dye in DNA oligonucleotides. Nucleic Acids Res. 1995 Mar 11; 23(5):753-60. PMID: 7708489; PMCID: PMC306755.
      157. Rentzeperis D, Marky LA, Dwyer TJ, Geierstanger BH, Pelton JG, Wemmer D. Interaction of minor groove ligands to an AAATT/AATTT site: correlation of thermodynamic characterization and solution structure. Biochemistry. 1995 Mar 07; 34(9):2937-45. PMID: 7893707.
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      158. Volkman BF, Nohaile MJ, Amy NK, Kustu S, Wemmer D. Three-dimensional solution structure of the N-terminal receiver domain of NTRC. Biochemistry. 1995 Jan 31; 34(4):1413-24. PMID: 7827089.
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      159. Geierstanger BH, Wemmer D. Complexes of the minor groove of DNA. Annu Rev Biophys Biomol Struct. 1995; 24:463-93. PMID: 7663124.
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      160. Pelton JG, Wemmer D. Heteronuclear NMR pulse sequences applied to biomolecules. Annu Rev Phys Chem. 1995; 46:139-67. PMID: 7495481.
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      161. Lee AL, Kanaar R, Rio DC, Wemmer D. Resonance assignments and solution structure of the second RNA-binding domain of sex-lethal determined by multidimensional heteronuclear magnetic resonance. Biochemistry. 1994 Nov 22; 33(46):13775-86. PMID: 7524663.
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      162. Geierstanger BH, Mrksich M, Dervan PB, Wemmer D. Design of a G.C-specific DNA minor groove-binding peptide. Science. 1994 Oct 28; 266(5185):646-50. PMID: 7939719.
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      163. Damberger FF, Pelton JG, Harrison CJ, Nelson HC, Wemmer D. Solution structure of the DNA-binding domain of the heat shock transcription factor determined by multidimensional heteronuclear magnetic resonance spectroscopy. Protein Sci. 1994 Oct; 3(10):1806-21. PMID: 7849597; PMCID: PMC2142621.
      164. Acedo M, Fàbrega C, Aviño A, Goodman M, Fagan P, Wemmer D, Eritja R. A simple method for N-15 labelling of exocyclic amino groups in synthetic oligodeoxynucleotides. Nucleic Acids Res. 1994 Aug 11; 22(15):2982-9. PMID: 8065910; PMCID: PMC310265.
      165. Singh SB, Wemmer D, Kollman PA. Relative binding affinities of distamycin and its analog to d(CGCAAGTTGGC).d(GCCAACTTGCG): comparison of simulation results with experiment. Proc Natl Acad Sci U S A. 1994 Aug 02; 91(16):7673-7. PMID: 8052641; PMCID: PMC44464.
      166. Geierstanger BH, Volkman BF, Kremer W, Wemmer D. Short peptide fragments derived from HMG-I/Y proteins bind specifically to the minor groove of DNA. Biochemistry. 1994 May 03; 33(17):5347-55. PMID: 8172908.
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      167. Geierstanger BH, Jacobsen JP, Mrksich M, Dervan PB, Wemmer D. Structural and dynamic characterization of the heterodimeric and homodimeric complexes of distamycin and 1-methylimidazole-2-carboxamide-netropsin bound to the minor groove of DNA. Biochemistry. 1994 Mar 15; 33(10):3055-62. PMID: 8130219.
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      168. Pagel MD, Wemmer D. Solution structure of a core peptide derived from scyllatoxin. Proteins. 1994 Mar; 18(3):205-15. PMID: 7515492.
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      169. Zhou HX, Lyu P, Wemmer D, Kallenbach NR. Alpha helix capping in synthetic model peptides by reciprocal side chain-main chain interactions: evidence for an N terminal "capping box". Proteins. 1994 Jan; 18(1):1-7. PMID: 8146119.
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      170. Wemmer D, Williams PG. Use of nuclear magnetic resonance in probing ligand-macromolecule interactions. Methods Enzymol. 1994; 239:739-67. PMID: 7830603.
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      171. Highsmith S, Kubinec M, Jaiswal DK, Morimoto H, Williams PG, Wemmer D. [2-3H]ATP synthesis and 3H NMR spectroscopy of enzyme-nucleotide complexes: ADP and ADP.Vi bound to myosin subfragment 1. J Biomol NMR. 1993 May; 3(3):325-34. PMID: 8358234.
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      172. Wemmer D, Wedemayer GJ, Glazer AN. Phycobilins of cryptophycean algae. Novel linkage of dihydrobiliverdin in a phycoerythrin 555 and a phycocyanin 645. J Biol Chem. 1993 Jan 25; 268(3):1658-69. PMID: 8420941.
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      173. Lyu PC, Wemmer D, Zhou HX, Pinker RJ, Kallenbach NR. Capping interactions in isolated alpha helices: position-dependent substitution effects and structure of a serine-capped peptide helix. Biochemistry. 1993 Jan 19; 32(2):421-5. PMID: 8422351.
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      174. Storrs RW, Truckses D, Wemmer D. Helix propagation in trifluoroethanol solutions. Biopolymers. 1992 Dec; 32(12):1695-702. PMID: 1472652.
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      175. Tomic MT, Somoza JR, Wemmer D, Park YW, Cho JM, Kim SH. 1H resonance assignments, secondary structure and general topology of single-chain monellin in solution as determined by 1H 2D-NMR. J Biomol NMR. 1992 Nov; 2(6):557-72. PMID: 1490107.
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      176. Mrksich M, Wade WS, Dwyer TJ, Geierstanger BH, Wemmer D, Dervan PB. Antiparallel side-by-side dimeric motif for sequence-specific recognition in the minor groove of DNA by the designed peptide 1-methylimidazole-2-carboxamide netropsin. Proc Natl Acad Sci U S A. 1992 Aug 15; 89(16):7586-90. PMID: 1323845; PMCID: PMC49755.
      177. Amaratunga M, Snowden-Ifft E, Wemmer D, Benight AS. Studies of DNA dumbbells. II. Construction and characterization of DNA dumbbells with a 16 base-pair duplex stem and Tn end loops (n = 2, 3, 4, 6, 8, 10, 14). Biopolymers. 1992 Jul; 32(7):865-79. PMID: 1391635.
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      178. Sastry SS, Spielmann HP, Dwyer TJ, Wemmer D, Hearst JE. Recent advances in the synthesis and structure determination of site specifically psoralen-modified DNA oligonucleotides. J Photochem Photobiol B. 1992 Jun 30; 14(1-2):65-79. PMID: 1432385.
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      179. Gaillard J, Albrand JP, Moulis JM, Wemmer D. Sequence-specific assignments of the 1H nuclear magnetic resonance spectra of reduced high-potential ferredoxin (HiPIP) from Chromatium vinosum. Biochemistry. 1992 Jun 23; 31(24):5632-9. PMID: 1610810.
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      180. Rye HS, Yue S, Wemmer D, Quesada MA, Haugland RP, Mathies RA, Glazer AN. Stable fluorescent complexes of double-stranded DNA with bis-intercalating asymmetric cyanine dyes: properties and applications. Nucleic Acids Res. 1992 Jun 11; 20(11):2803-12. PMID: 1614866; PMCID: PMC336925.
      181. Werner MH, Wemmer D. Identification of a protein-binding surface by differential amide hydrogen-exchange measurements. Application to Bowman-Birk serine-protease inhibitor. J Mol Biol. 1992 Jun 05; 225(3):873-89. PMID: 1602487.
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      182. Wedemayer GJ, Kidd DG, Wemmer D, Glazer AN. Phycobilins of cryptophycean algae. Occurrence of dihydrobiliverdin and mesobiliverdin in cryptomonad biliproteins. J Biol Chem. 1992 Apr 15; 267(11):7315-31. PMID: 1559975.
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      183. Werner MH, Wemmer D. Three-dimensional structure of soybean trypsin/chymotrypsin Bowman-Birk inhibitor in solution. Biochemistry. 1992 Feb 04; 31(4):999-1010. PMID: 1734975.
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      184. Kallick DA, Wemmer D. 1H NMR of 5'CGCGTATATACGCG3', a duplex and a four-membered loop. Nucleic Acids Res. 1991 Nov 11; 19(21):6041-6. PMID: 1945888; PMCID: PMC329064.
      185. Gehring K, Williams PG, Pelton JG, Morimoto H, Wemmer D. Tritium NMR spectroscopy of ligand binding to maltose-binding protein. Biochemistry. 1991 Jun 04; 30(22):5524-31. PMID: 2036421.
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      186. McIntire WS, Wemmer D, Chistoserdov A, Lidstrom ME. A new cofactor in a prokaryotic enzyme: tryptophan tryptophylquinone as the redox prosthetic group in methylamine dehydrogenase. Science. 1991 May 10; 252(5007):817-24. PMID: 2028257.
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      187. Werner MH, Wemmer D. 1H assignments and secondary structure determination of the soybean trypsin/chymotrypsin Bowman-Birk inhibitor. Biochemistry. 1991 Apr 09; 30(14):3356-64. PMID: 2012801.
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      188. Wedemayer GJ, Wemmer D, Glazer AN. Phycobilins of cryptophycean algae. Structures of novel bilins with acryloyl substituents from phycoerythrin 566. J Biol Chem. 1991 Mar 15; 266(8):4731-41. PMID: 2002022.
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      189. Pease AC, Wemmer D. Characterization of the secondary structure and melting of a self-cleaved RNA hammerhead domain by 1H NMR spectroscopy. Biochemistry. 1990 Sep 25; 29(38):9039-46. PMID: 1702996.
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      190. Pelton JG, Wemmer D. Structure and dynamics of distamycin A with d(CGCAAATTGGC):d(GCCAATTTGCG) at low drug:DNA ratios. J Biomol Struct Dyn. 1990 Aug; 8(1):81-97. PMID: 2275799.
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      191. Pease JH, Storrs RW, Wemmer D. Folding and activity of hybrid sequence, disulfide-stabilized peptides. Proc Natl Acad Sci U S A. 1990 Aug; 87(15):5643-7. PMID: 2377603; PMCID: PMC54383.
      192. Snowden-Ifft EA, Wemmer D. Characterization of the structure and melting of DNAs containing backbone nicks and gaps. Biochemistry. 1990 Jun 26; 29(25):6017-25. PMID: 2166572.
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      193. Janes SM, Mu D, Wemmer D, Smith AJ, Kaur S, Maltby D, Burlingame AL, Klinman JP. A new redox cofactor in eukaryotic enzymes: 6-hydroxydopa at the active site of bovine serum amine oxidase. Science. 1990 May 25; 248(4958):981-7. PMID: 2111581.
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      194. Pelton JG, Wemmer D. Structural characterization of a 2:1 distamycin A.d(CGCAAATTGGC) complex by two-dimensional NMR. Proc Natl Acad Sci U S A. 1989 Aug; 86(15):5723-7. PMID: 2762292; PMCID: PMC297702.
      195. Pease JH, Kumar NV, Schweitz H, Kallenbach NR, Wemmer D. NMR studies of toxin III from the sea anemone Radianthus paumotensis and comparison of its secondary structure with related toxins. Biochemistry. 1989 Mar 07; 28(5):2199-204. PMID: 2566327.
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      196. Kintanar A, Huang WC, Schindele DC, Wemmer D, Drobny G. Dynamics of bases in hydrated [d(CGCGAATTCGCG)]2. Biochemistry. 1989 Jan 10; 28(1):282-93. PMID: 2706252.
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      197. Pease JH, Wemmer D. Solution structure of apamin determined by nuclear magnetic resonance and distance geometry. Biochemistry. 1988 Nov 01; 27(22):8491-8. PMID: 3242598.
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      198. Pelton JG, Wemmer D. Structural modeling of the distamycin A-d(CGCGAATTCGCG)2 complex using 2D NMR and molecular mechanics. Biochemistry. 1988 Oct 18; 27(21):8088-96. PMID: 3233197.
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      199. Kleanthous C, Wemmer D, Schachman HK. The role of an active site histidine in the catalytic mechanism of aspartate transcarbamoylase. J Biol Chem. 1988 Sep 15; 263(26):13062-7. PMID: 3047117.
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      200. Kumar NV, Wemmer D, Kallenbach NR. Structure of P401 (mast cell degranulating peptide) in solution. Biophys Chem. 1988 Aug; 31(1-2):113-9. PMID: 3233281.
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      201. Kim SH, Tomic MT, Wemmer D, Pearlman D, Holbrook S. Structure of DNA damaged by UV and psoralen. Biochem Pharmacol. 1988 May 01; 37(9):1791. PMID: 3377835.
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      202. Benight AS, Schurr JM, Flynn PF, Reid BR, Wemmer D. Melting of a self-complementary DNA minicircle. Comparison of optical melting theory with exchange broadening of the nuclear magnetic resonance spectrum. J Mol Biol. 1988 Mar 20; 200(2):377-99. PMID: 2836596.
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      203. Tomic MT, Wemmer D, Kim SH. Structure of a psoralen cross-linked DNA in solution by nuclear magnetic resonance. Science. 1987 Dec 18; 238(4834):1722-5. PMID: 3686011.
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      204. Srivenugopal KS, Wemmer D, Morris DR. Aggregation of DNA by analogs of spermidine; enzymatic and structural studies. Nucleic Acids Res. 1987 Mar 25; 15(6):2563-80. PMID: 3031604; PMCID: PMC340669.
      205. Wemmer D, Kumar NV, Metrione RM, Lazdunski M, Drobny G, Kallenbach NR. NMR analysis and sequence of toxin II from the sea anemone Radianthus paumotensis. Biochemistry. 1986 Nov 04; 25(22):6842-9. PMID: 2879552.
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      206. Klevit RE, Wemmer D, Reid BR. 1H NMR studies on the interaction between distamycin A and a symmetrical DNA dodecamer. Biochemistry. 1986 Jun 03; 25(11):3296-303. PMID: 3730362.
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      207. Klevit RE, Blumenthal DK, Wemmer D, Krebs EG. Interaction of calmodulin and a calmodulin-binding peptide from myosin light chain kinase: major spectral changes in both occur as the result of complex formation. Biochemistry. 1985 Dec 31; 24(27):8152-7. PMID: 3841496.
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      208. Wemmer D, Benight AS. Preparation and melting of single strand circular DNA loops. Nucleic Acids Res. 1985 Dec 09; 13(23):8611-21. PMID: 4080549; PMCID: PMC322156.
      209. Wemmer D, Wand AJ, Seeman NC, Kallenbach NR. NMR analysis of DNA junctions: imino proton NMR studies of individual arms and intact junction. Biochemistry. 1985 Oct 08; 24(21):5745-9. PMID: 4084489.
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      210. Wemmer D, Srivenugopal KS, Reid BR, Morris DR. Nuclear magnetic resonance studies of polyamine binding to a defined DNA sequence. J Mol Biol. 1985 Sep 20; 185(2):457-9. PMID: 4057253.
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      211. Weber PL, Wemmer D, Reid BR. 1H NMR studies of lambda cro repressor. 2. Sequential resonance assignments of the 1H NMR spectrum. Biochemistry. 1985 Aug 13; 24(17):4553-62. PMID: 2933070.
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      212. Hare DR, Ribeiro NS, Wemmer D, Reid BR. Complete assignment of the imino protons of Escherichia coli valine transfer RNA: two-dimensional NMR studies in water. Biochemistry. 1985 Jul 30; 24(16):4300-6. PMID: 3902082.
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      213. Langowski J, Fujimoto BS, Wemmer D, Benight AS, Drobny G, Shibata JH, Schurr JM. Deformational dynamics and NMR relaxation of supercoiled DNAs. Biopolymers. 1985 Jun; 24(6):1023-56. PMID: 4027335.
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      214. Wemmer D, Chou SH, Hare DR, Reid BR. Duplex-hairpin transitions in DNA: NMR studies on CGCGTATACGCG. Nucleic Acids Res. 1985 May 24; 13(10):3755-72. PMID: 4011441; PMCID: PMC341271.
      215. Wemmer D, Chou SH, Reid BR. Sequence-specific recognition of DNA. Nuclear magnetic resonance assignments and structural comparison of wild-type and mutant lambda OR3 operator DNA. J Mol Biol. 1984 Nov 25; 180(1):41-60. PMID: 6096560.
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      216. Roberts JK, Callis J, Wemmer D, Walbot V, Jardetzky O. Mechanisms of cytoplasmic pH regulation in hypoxic maize root tips and its role in survival under hypoxia. Proc Natl Acad Sci U S A. 1984 Jun; 81(11):3379-83. PMID: 6587355; PMCID: PMC345511.
      217. Chou SH, Wemmer D, Hare DR, Reid BR. Sequence-specific recognition of DNA: NMR studies of the imino protons of a synthetic RNA polymerase promoter. Biochemistry. 1984 May 08; 23(10):2257-62. PMID: 6329267.
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      218. Wemmer D, Chou SH, Hare DR, Reid BR. Sequence-specific recognition of DNA: assignment of nonexchangeable proton resonances in the consensus Pribnow promoter DNA sequence by two-dimensional NMR. Biochemistry. 1984 May 08; 23(10):2262-8. PMID: 6329268.
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      219. Roberts JK, Wemmer D, Jardetzky O. Measurement of mitochondrial ATPase activity in maize root tips by saturation transfer p nuclear magnetic resonance. Plant Physiol. 1984 Mar; 74(3):632-9. PMID: 16663473.
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      220. Hare DR, Wemmer D, Chou SH, Drobny G, Reid BR. Assignment of the non-exchangeable proton resonances of d(C-G-C-G-A-A-T-T-C-G-C-G) using two-dimensional nuclear magnetic resonance methods. J Mol Biol. 1983 Dec 15; 171(3):319-36. PMID: 6317867.
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      221. Chou SH, Hare DR, Wemmer D, Reid BR. Sequence-specific recognition of deoxyribonucleic acid. Chemical synthesis and nuclear magnetic resonance assignment of the imino protons of lambda OR3 operator deoxyribonucleic acid. Biochemistry. 1983 Jun 21; 22(13):3037-41. PMID: 6309214.
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      222. Wemmer D, Kallenbach NR. Structure of apamin in solution: a two-dimensional nuclear magnetic resonance study. Biochemistry. 1983 Apr 12; 22(8):1901-6. PMID: 6849893.
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      223. Wemmer D, Wade-Jardetzky N, Robin E, Jardetzky O. Changes in the phosphorus metabolism of a diving turtle observed by 31P-NMR. Biochim Biophys Acta. 1982 Jun 08; 720(3):281-7. PMID: 7104398.
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      224. Gonzalez-Mendez R, Wemmer D, Hahn G, Wade-Jardetzky N, Jardetzky O. Continuous-flow NMR culture system for mammalian cells. Biochim Biophys Acta. 1982 Jun 08; 720(3):274-80. PMID: 7104397.
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      225. Roberts JK, Wemmer D, Ray PM, Jardetzky O. Regulation of Cytoplasmic and Vacuolar pH in Maize Root Tips under Different Experimental Conditions. Plant Physiol. 1982 Jun; 69(6):1344-7. PMID: 16662399.
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      226. Ribeiro AA, Wemmer D, Bray RP, Jardetzky O. pH dependence of the high-resolution proton nuclear magnetic resonance spectrum of the lac repressor headpiece. Biochemistry. 1981 Jun 09; 20(12):3346-50. PMID: 7260038.
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      227. Wemmer D, Shvo H, Ribeiro AA, Bray RP, Jardetzky O. High-resolution proton nuclear magnetic resonance studies of the exchangeable resonances of the lac repressor headpiece. Biochemistry. 1981 Jun 09; 20(12):3351-4. PMID: 7260039.
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      228. Ribeiro AA, Wemmer D, Bray RP, Jardetzky O. A folded structure for the lac-repressor headpiece. Biochem Biophys Res Commun. 1981 Mar 31; 99(2):668-74. PMID: 7236292.
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      229. Hogan M, Wemmer D, Bray RP, Wade-Jardetzky N, Jardetzky O. On the interaction of the lac repressor headpiece with nucleic acids. FEBS Lett. 1981 Feb 23; 124(2):202-3. PMID: 6262117.
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      230. Ribeiro AA, Wemmer D, Bray RP, Wade-Jardetzky NG, Jardetzky O. High-resolution nuclear magnetic resonance studies of the Lac repressor. 1. Assignments of tyrosine resonances in the N-terminal headpiece. Biochemistry. 1981 Feb 17; 20(4):818-23. PMID: 7011373.
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      231. Wemmer D, Ribeiro AA, Bray RP, Wade-Jardetzky NG, Jardetzky O. High-resolution nuclear magnetic resonance studies of the Lac repressor. 3. Unfolding of the Lac repressor headpiece. Biochemistry. 1981 Feb 17; 20(4):829-33. PMID: 7213616.
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      232. Ribeiro AA, Wemmer D, Bray RP, Wade-Jardetzky NG, Jardetzky O. High-resolution nuclear magnetic resonance studies of the Lac repressor. 2. Partial analysis of the aliphatic region of the Lac repressor headpiece spectrum. Biochemistry. 1981 Feb 17; 20(4):823-9. PMID: 7011374.
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      233. Arnold LE, Huestis RD, Wemmer D, Smeltzer DJ. Differential effect of amphetamine optical isomers on Bender Gestalt performance of the minimally brain dysfunctioned. J Learn Disabil. 1978 Mar; 11(3):127-32. PMID: 353207.
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      234. Arnold LE, Huestis RD, Smeltzer DJ, Scheib J, Wemmer D, Colner G. Levoamphetamine vs dextroamphetamine in minimal brain dysfunction. Replication, time response, and differential effect by diagnostic group and family rating. Arch Gen Psychiatry. 1976 Mar; 33(3):292-301. PMID: 769721.
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