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    Schild, David

    TitleBiologist Staff Sci/Engr
    SchoolLawrence Berkeley National Lab
    DepartmentBiological Systems & Eng
    Address1 Cyclotron Road
    Berkeley CA 94720
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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Yue Y, Leung SG, Liu Y, Huang Y, Grundt K, Østvold AC, Jen KY, Schild D, Mao JH, Wiese C. Nucks1 synergizes with Trp53 to promote radiation lymphomagenesis in mice. Oncotarget. 2016 Sep 20; 7(38):61874-61889. PMID: 27542204.
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      2. Parplys AC, Zhao W, Sharma N, Groesser T, Liang F, Maranon DG, Leung SG, Grundt K, Dray E, Idate R, Østvold AC, Schild D, Sung P, Wiese C. NUCKS1 is a novel RAD51AP1 paralog important for homologous recombination and genome stability. Nucleic Acids Res. 2015 Nov 16; 43(20):9817-34. PMID: 26323318; PMCID: PMC4787752.
      3. Williams GJ, SilDas S, Anand A, Schild D, Tainer JA. 204 Structural insights into the RAD51 paralog complexes reveal molecular details of disease causing mutations. J Biomol Struct Dyn. 2015; 33 Suppl 1:137. PMID: 26103414.
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      4. Parplys AC, Kratz K, Speed MC, Leung SG, Schild D, Wiese C. RAD51AP1-deficiency in vertebrate cells impairs DNA replication. DNA Repair (Amst). 2014 Dec; 24:87-97. PMID: 25288561; PMCID: PMC4254361.
      5. Dunlop MH, Dray E, Zhao W, San Filippo J, Tsai MS, Leung SG, Schild D, Wiese C, Sung P. Mechanistic insights into RAD51-associated protein 1 (RAD51AP1) action in homologous DNA repair. J Biol Chem. 2012 Apr 06; 287(15):12343-7. PMID: 22375013; PMCID: PMC3320983.
      6. Dunlop MH, Dray E, Zhao W, Tsai MS, Wiese C, Schild D, Sung P. RAD51-associated protein 1 (RAD51AP1) interacts with the meiotic recombinase DMC1 through a conserved motif. J Biol Chem. 2011 Oct 28; 286(43):37328-34. PMID: 21903585; PMCID: PMC3199480.
      7. Dray E, Dunlop MH, Kauppi L, San Filippo J, Wiese C, Tsai MS, Begovic S, Schild D, Jasin M, Keeney S, Sung P. Molecular basis for enhancement of the meiotic DMC1 recombinase by RAD51 associated protein 1 (RAD51AP1). Proc Natl Acad Sci U S A. 2011 Mar 01; 108(9):3560-5. PMID: 21307306; PMCID: PMC3048120.
      8. Dray E, Etchin J, Wiese C, Saro D, Williams GJ, Hammel M, Yu X, Galkin VE, Liu D, Tsai MS, Sy SM, Schild D, Egelman E, Chen J, Sung P. Enhancement of RAD51 recombinase activity by the tumor suppressor PALB2. Nat Struct Mol Biol. 2010 Oct; 17(10):1255-9. PMID: 20871616; PMCID: PMC2950913.
      9. Zafar F, Seidler SB, Kronenberg A, Schild D, Wiese C. Homologous recombination contributes to the repair of DNA double-strand breaks induced by high-energy iron ions. Radiat Res. 2010 Jan; 173(1):27-39. PMID: 20041757.
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      10. Schild D, Wiese C. Overexpression of RAD51 suppresses recombination defects: a possible mechanism to reverse genomic instability. Nucleic Acids Res. 2010 Mar; 38(4):1061-70. PMID: 19942681; PMCID: PMC2831301.
      11. Wiese C, Dray E, Groesser T, San Filippo J, Shi I, Collins DW, Tsai MS, Williams GJ, Rydberg B, Sung P, Schild D. Promotion of homologous recombination and genomic stability by RAD51AP1 via RAD51 recombinase enhancement. Mol Cell. 2007 Nov 09; 28(3):482-90. PMID: 17996711; PMCID: PMC2169287.
      12. Kovalenko OV, Wiese C, Schild D. RAD51AP2, a novel vertebrate- and meiotic-specific protein, shares a conserved RAD51-interacting C-terminal domain with RAD51AP1/PIR51. Nucleic Acids Res. 2006; 34(18):5081-92. PMID: 16990250; PMCID: PMC1636435.
      13. Wiese C, Hinz JM, Tebbs RS, Nham PB, Urbin SS, Collins DW, Thompson LH, Schild D. Disparate requirements for the Walker A and B ATPase motifs of human RAD51D in homologous recombination. Nucleic Acids Res. 2006; 34(9):2833-43. PMID: 16717288; PMCID: PMC1464408.
      14. Lio YC, Schild D, Brenneman MA, Redpath JL, Chen DJ. Human Rad51C deficiency destabilizes XRCC3, impairs recombination, and radiosensitizes S/G2-phase cells. J Biol Chem. 2004 Oct 01; 279(40):42313-20. PMID: 15292210.
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      15. Thompson LH, Schild D. Recombinational DNA repair and human disease. Mutat Res. 2002 Nov 30; 509(1-2):49-78. PMID: 12427531.
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      16. Wiese C, Collins DW, Albala JS, Thompson LH, Kronenberg A, Schild D. Interactions involving the Rad51 paralogs Rad51C and XRCC3 in human cells. Nucleic Acids Res. 2002 Feb 15; 30(4):1001-8. PMID: 11842112; PMCID: PMC100332.
      17. Liu N, Schild D, Thelen MP, Thompson LH. Involvement of Rad51C in two distinct protein complexes of Rad51 paralogs in human cells. Nucleic Acids Res. 2002 Feb 15; 30(4):1009-15. PMID: 11842113; PMCID: PMC100342.
      18. Sigurdsson S, Van Komen S, Bussen W, Schild D, Albala JS, Sung P. Mediator function of the human Rad51B-Rad51C complex in Rad51/RPA-catalyzed DNA strand exchange. Genes Dev. 2001 Dec 15; 15(24):3308-18. PMID: 11751636; PMCID: PMC312844.
      19. Miller KA, Yoshikawa DM, McConnell IR, Clark R, Schild D, Albala JS. RAD51C interacts with RAD51B and is central to a larger protein complex in vivo exclusive of RAD51. J Biol Chem. 2002 Mar 08; 277(10):8406-11. PMID: 11744692.
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      20. Thompson LH, Schild D. Homologous recombinational repair of DNA ensures mammalian chromosome stability. Mutat Res. 2001 Jun 02; 477(1-2):131-53. PMID: 11376695.
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      21. Takata M, Sasaki MS, Tachiiri S, Fukushima T, Sonoda E, Schild D, Thompson LH, Takeda S. Chromosome instability and defective recombinational repair in knockout mutants of the five Rad51 paralogs. Mol Cell Biol. 2001 Apr; 21(8):2858-66. PMID: 11283264; PMCID: PMC86915.
      22. Schild D, Lio YC, Collins DW, Tsomondo T, Chen DJ. Evidence for simultaneous protein interactions between human Rad51 paralogs. J Biol Chem. 2000 Jun 02; 275(22):16443-9. PMID: 10749867.
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      23. Thompson LH, Schild D. The contribution of homologous recombination in preserving genome integrity in mammalian cells. Biochimie. 1999 Jan-Feb; 81(1-2):87-105. PMID: 10214914.
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      24. Liu N, Lamerdin JE, Tebbs RS, Schild D, Tucker JD, Shen MR, Brookman KW, Siciliano MJ, Walter CA, Fan W, Narayana LS, Zhou ZQ, Adamson AW, Sorensen KJ, Chen DJ, Jones NJ, Thompson LH. XRCC2 and XRCC3, new human Rad51-family members, promote chromosome stability and protect against DNA cross-links and other damages. Mol Cell. 1998 May; 1(6):783-93. PMID: 9660962.
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      25. Dosanjh MK, Collins DW, Fan W, Lennon GG, Albala JS, Shen Z, Schild D. Isolation and characterization of RAD51C, a new human member of the RAD51 family of related genes. Nucleic Acids Res. 1998 Mar 01; 26(5):1179-84. PMID: 9469824; PMCID: PMC147393.
      26. Schild D. Suppression of a new allele of the yeast RAD52 gene by overexpression of RAD51, mutations in srs2 and ccr4, or mating-type heterozygosity. Genetics. 1995 May; 140(1):115-27. PMID: 7635279; PMCID: PMC1206541.
      27. Schild D. ITEM OF INTEREST. Phys Occup Ther Pediatr. 1993; 12(4):117-118. PMID: 28368732.
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      28. Schild D, Glassner BJ, Mortimer RK, Carlson M, Laurent BC. Identification of RAD16, a yeast excision repair gene homologous to the recombinational repair gene RAD54 and to the SNF2 gene involved in transcriptional activation. Yeast. 1992 May; 8(5):385-95. PMID: 1626430.
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      29. Emery HS, Schild D, Kellogg DE, Mortimer RK. Sequence of RAD54, a Saccharomyces cerevisiae gene involved in recombination and repair. Gene. 1991 Jul 31; 104(1):103-6. PMID: 1916269.
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      30. Chang FH, Barnes TS, Schild D, Gnirke A, Bleskan J, Patterson D. Expression of a human cDNA encoding a protein containing GAR synthetase, AIR synthetase, and GAR transformylase corrects the defects in mutant Chinese hamster ovary cells lacking these activities. Somat Cell Mol Genet. 1991 Jul; 17(4):411-20. PMID: 1887337.
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      31. Mortimer RK, Schild D, Contopoulou CR, Kans JA. Genetic and physical maps of Saccharomyces cerevisiae. Methods Enzymol. 1991; 194:827-63. PMID: 2005826.
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      32. Schild D, Brake AJ, Kiefer MC, Young D, Barr PJ. Cloning of three human multifunctional de novo purine biosynthetic genes by functional complementation of yeast mutations. Proc Natl Acad Sci U S A. 1990 Apr; 87(8):2916-20. PMID: 2183217; PMCID: PMC53804.
      33. Mortimer RK, Schild D, Contopoulou CR, Kans JA. Genetic map of Saccharomyces cerevisiae, edition 10. Yeast. 1989 Sep-Oct; 5(5):321-403. PMID: 2678811.
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      34. Cole GM, Schild D, Mortimer RK. Two DNA repair and recombination genes in Saccharomyces cerevisiae, RAD52 and RAD54, are induced during meiosis. Mol Cell Biol. 1989 Jul; 9(7):3101-4. PMID: 2506437; PMCID: PMC362781.
      35. Cole GM, Schild D, Lovett ST, Mortimer RK. Regulation of RAD54- and RAD52-lacZ gene fusions in Saccharomyces cerevisiae in response to DNA damage. Mol Cell Biol. 1987 Mar; 7(3):1078-84. PMID: 3550429; PMCID: PMC365179.
      36. Mortimer RK, Schild D. Genetic map of Saccharomyces cerevisiae, edition 9. Microbiol Rev. 1985 Sep; 49(3):181-213. PMID: 2995780; PMCID: PMC373033.
      37. Schild D, Mortimer RK. A mapping method for Saccharomyces cerevisiae using rad52-induced chromosome loss. Genetics. 1985 Aug; 110(4):569-89. PMID: 3896924; PMCID: PMC1202582.
      38. Schild D, Johnston J, Chang C, Mortimer RK. Cloning and mapping of Saccharomyces cerevisiae photoreactivation gene PHR1. Mol Cell Biol. 1984 Sep; 4(9):1864-70. PMID: 6092943; PMCID: PMC368996.
      39. Schild D, Konforti B, Perez C, Gish W, Mortimer R. Isolation and characterization of yeast DNA repair genes : I. Cloning of the RAD52 gene. Curr Genet. 1983 Apr; 7(2):85-92. PMID: 24173148.
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      40. Mortimer RK, Contopoulou R, Schild D. Mitotic chromosome loss in a radiation-sensitive strain of the yeast Saccharomyces cerevisiae. Proc Natl Acad Sci U S A. 1981 Sep; 78(9):5778-82. PMID: 7029545; PMCID: PMC348859.
      41. Schild D, Ananthaswamy HN, Mortimer RK. An endomitotic effect of a cell cycle mutation of Saccharomyces cerevisiae. Genetics. 1981 Mar-Apr; 97(3-4):551-62. PMID: 7028565; PMCID: PMC1214411.
      42. Mortimer RK, Schild D. Genetic map of Saccharomyces cerevisiae. Microbiol Rev. 1980 Dec; 44(4):519-71. PMID: 7010111; PMCID: PMC373195.
      43. Schild D, Byers B. Diploid spore formation and other meiotic effects of two cell-division-cycle mutations of Saccharomyces cerevisiae. Genetics. 1980 Dec; 96(4):859-76. PMID: 7021319; PMCID: PMC1219305.

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