Loading...

Herr, Amy

TitleBiological Faculty Engineer
InstitutionLawrence Berkeley National Lab
DepartmentBiological Systems & Eng
Address1 Cyclotron Road
Berkeley CA 94720
Phone510/666-3396
vCardDownload vCard

    Collapse Research 
    Collapse Research Activities and Funding
    Advanced Cancer Classification via Single-Cell Electrophoretic Cytopathology
    NIH/NCI R33CA225296Sep 30, 2017 - Aug 31, 2020
    Role: Principal Investigator
    Multiplexed isoform quantification in HER2-positive breast cancer
    NIH/NCI R01CA203018Dec 1, 2015 - Nov 30, 2019
    Role: Principal Investigator
    Measuring biophysical & protein signaling indicators of invasion potential in single-circulating tumor cells
    NIH/NIBIB R21EB019880Sep 11, 2015 - Jun 30, 2017
    Role: Principal Investigator
    Microfluidic Western Blotting for Targeted Proteomic Analysis of Single Circulating Tumor Cells
    NIH/NCI R21CA183679Jun 9, 2015 - May 31, 2018
    Role: Principal Investigator
    Immersive Team-Based Design in Undergraduate Bioengineering Education
    NIH/NIBIB R25EB013068Apr 1, 2011 - Feb 28, 2021
    Role: Principal Investigator
    Towards High Throughput Proteomics: A Micro/nanofluidic Framework for Blotless W
    NIH DP2OD007294Sep 30, 2010 - Jun 30, 2015
    Role: Principal Investigator
    2009 Microfluidics. Physics &Chemistry of Gordon Research Conference
    NIH/NIBIB R13EB009560Apr 1, 2009 - Mar 31, 2010
    Role: Principal Investigator

    Collapse Bibliographic 
    Collapse Publications
    Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
    List All   |   Timeline
    1. Rosàs-Canyelles E, Dai T, Li S, Herr A. Mouse-to-mouse variation in maturation heterogeneity of smooth muscle cells. Lab Chip. 2018 May 25. PMID: 29796562.
      View in: PubMed
    2. Kang CC, Ward TM, Bockhorn J, Schiffman C, Huang H, Pegram MD, Herr A. Electrophoretic cytopathology resolves ERBB2 forms with single-cell resolution. NPJ Precis Oncol. 2018; 2:10. PMID: 29872719.
      View in: PubMed
    3. Yamauchi KA, Tentori AM, Herr A. Arrayed isoelectric focusing using photopatterned multi-domain hydrogels. Electrophoresis. 2018 Apr; 39(8):1040-1047. PMID: 29385243.
      View in: PubMed
    4. Lin JG, Kang CC, Zhou Y, Huang H, Herr A, Kumar S. Linking invasive motility to protein expression in single tumor cells. Lab Chip. 2018 01 16; 18(2):371-384. PMID: 29299576.
      View in: PubMed
    5. Zhang Y, Chan P, Herr A. Rapid Capture and Release of Nucleic Acids through a Reversible Photo-cycloaddition Reaction in the Psoralen-functionalized Hydrogel. Angew Chem Int Ed Engl. 2018 Jan 07. PMID: 29316080.
      View in: PubMed
    6. Su EJ, Herr A. Electrophoretic cytometry of adherent cells. Lab Chip. 2017 12 05; 17(24):4312-4323. PMID: 29120467.
      View in: PubMed
    7. Pan Q, Herr A. Geometry-induced injection dispersion in single-cell protein electrophoresis. Anal Chim Acta. 2018 Feb 13; 1000:214-222. PMID: 29289313.
      View in: PubMed
    8. Vlassakis J, Herr A. Joule Heating-Induced Dispersion in Open Microfluidic Electrophoretic Cytometry. Anal Chem. 2017 Dec 05; 89(23):12787-12796. PMID: 29110464.
      View in: PubMed
    9. Neira HD, Herr A. Kinetic Analysis of Enzymes Immobilized in Porous Film Arrays. Anal Chem. 2017 Oct 03; 89(19):10311-10320. PMID: 28858525.
      View in: PubMed
    10. Abdel-Sayed P, Yamauchi KA, Gerver RE, Herr A. Fabrication of an Open Microfluidic Device for Immunoblotting. Anal Chem. 2017 Sep 19; 89(18):9643-9648. PMID: 28825964.
      View in: PubMed
    11. Sinkala E, Sollier-Christen E, Renier C, Rosàs-Canyelles E, Che J, Heirich K, Duncombe TA, Vlassakis J, Yamauchi KA, Huang H, Jeffrey SS, Herr A. Profiling protein expression in circulating tumour cells using microfluidic western blotting. Nat Commun. 2017 Mar 23; 8:14622. PMID: 28332571.
      View in: PubMed
    12. Kim JJ, Sinkala E, Herr A. High-selectivity cytology via lab-on-a-disc western blotting of individual cells. Lab Chip. 2017 02 28; 17(5):855-863. PMID: 28165521.
      View in: PubMed
    13. Yamauchi KA, Herr A. Subcellular western blotting of single cells. Microsyst Nanoeng. 2017; 3. PMID: 29333327.
      View in: PubMed
    14. Pan Y, Sackmann EK, Wypisniak K, Hornsby M, Datwani SS, Herr A. Determination of equilibrium dissociation constants for recombinant antibodies by high-throughput affinity electrophoresis. Sci Rep. 2016 Dec 23; 6:39774. PMID: 28008969.
      View in: PubMed
    15. Tentori AM, Yamauchi KA, Herr A. Corrigendum: Detection of Isoforms Differing by a Single Charge Unit in Individual Cells. Angew Chem Int Ed Engl. 2016 Dec 05; 55(49):15200. PMID: 27897425.
      View in: PubMed
    16. Tentori AM, Yamauchi KA, Herr A. Detection of Isoforms Differing by a Single Charge Unit in Individual Cells. Angew Chem Int Ed Engl. 2016 Sep 26; 55(40):12431-5. PMID: 27595864.
      View in: PubMed
    17. Kang CC, Yamauchi KA, Vlassakis J, Sinkala E, Duncombe TA, Herr A. Single cell-resolution western blotting. Nat Protoc. 2016 08; 11(8):1508-30. PMID: 27466711.
      View in: PubMed
    18. Kapil MA, Pan Y, Duncombe TA, Herr A. Kinetic Rate Determination via Electrophoresis along a Varying Cross-Section Microchannel. Anal Chem. 2016 Apr 05; 88(7):3669-76. PMID: 26963604.
      View in: PubMed
    19. Duncombe TA, Kang CC, Maity S, Ward TM, Pegram MD, Murthy N, Herr A. Hydrogel Pore-Size Modulation for Enhanced Single-Cell Western Blotting. Adv Mater. 2016 Jan 13; 28(2):327-334. PMID: 26567472; PMCID: PMC4708057 [Available on 01/01/17].
    20. Vlassakis J, Herr A. Effect of Polymer Hydration State on In-Gel Immunoassays. Anal Chem. 2015 Nov 03; 87(21):11030-8. PMID: 26457450.
      View in: PubMed
    21. Duncombe TA, Tentori AM, Herr A. Microfluidics: reframing biological enquiry. Nat Rev Mol Cell Biol. 2015 Sep; 16(9):554-67. PMID: 26296163.
      View in: PubMed
    22. Kellenberger CA, Sales-Lee J, Pan Y, Gassaway MM, Herr A, Hammond MC. A minimalist biosensor: Quantitation of cyclic di-GMP using the conformational change of a riboswitch aptamer. RNA Biol. 2015; 12(11):1189-97. PMID: 26114964; PMCID: PMC4829349.
    23. Lin R, Skandarajah A, Gerver RE, Neira HD, Fletcher DA, Herr A. A lateral electrophoretic flow diagnostic assay. Lab Chip. 2015 Mar 21; 15(6):1488-96. PMID: 25608872; PMCID: PMC4383188.
    24. Sinkala E, Herr A. Single-Cell Western Blotting. Methods Mol Biol. 2015; 1346:1-9. PMID: 26542711.
      View in: PubMed
    25. Chung M, Kim D, Herr A. Polymer sieving matrices in microanalytical electrophoresis. Analyst. 2014 Nov 21; 139(22):5635-54. PMID: 25195612.
      View in: PubMed
    26. Gerver RE, Herr A. Microfluidic Western blotting of low-molecular-mass proteins. Anal Chem. 2014 Nov 04; 86(21):10625-32. PMID: 25268977; PMCID: PMC4222625.
    27. Pan Y, Duncombe TA, Kellenberger CA, Hammond MC, Herr A. High-throughput electrophoretic mobility shift assays for quantitative analysis of molecular binding reactions. Anal Chem. 2014 Oct 21; 86(20):10357-64. PMID: 25233437; PMCID: PMC4204909.
    28. Kang CC, Lin JM, Xu Z, Kumar S, Herr A. Single-cell Western blotting after whole-cell imaging to assess cancer chemotherapeutic response. Anal Chem. 2014 Oct 21; 86(20):10429-36. PMID: 25226230; PMCID: PMC4204918.
    29. Hughes AJ, Spelke DP, Xu Z, Kang CC, Schaffer DV, Herr A. Single-cell western blotting. Nat Methods. 2014 Jul; 11(7):749-55. PMID: 24880876; PMCID: PMC4077215.
    30. Pan Y, Karns K, Herr A. Microfluidic electrophoretic mobility shift assays for quantitative biochemical analysis. Electrophoresis. 2014 Aug; 35(15):2078-90. PMID: 24591076.
      View in: PubMed
    31. Tentori AM, Herr A. Performance implications of chemical mobilization after microchannel IEF. Electrophoresis. 2014 May; 35(10):1453-60. PMID: 24590929.
      View in: PubMed
    32. Kapil MA, Herr A. Binding kinetic rates measured via electrophoretic band crossing in a pseudohomogeneous format. Anal Chem. 2014 Mar 04; 86(5):2601-9. PMID: 24552202.
      View in: PubMed
    33. Araz MK, Apori AA, Salisbury CM, Herr A. Microfluidic barcode assay for antibody-based confirmatory diagnostics. Lab Chip. 2013 Oct 07; 13(19):3910-20. PMID: 23925585.
      View in: PubMed
    34. Herr A. Disruptive by design: a perspective on engineering in analytical chemistry. Anal Chem. 2013 Aug 20; 85(16):7622-8. PMID: 23924345; PMCID: PMC3855236.
    35. Chung M, Kim D, Herr A. Microchamber Western blotting using poly-L-lysine conjugated polyacrylamide gel for blotting of sodium dodecyl sulfate coated proteins. Anal Chem. 2013 Aug 20; 85(16):7753-61. PMID: 23848185.
      View in: PubMed
    36. Kim D, Herr A. Protein immobilization techniques for microfluidic assays. Biomicrofluidics. 2013; 7(4):41501. PMID: 24003344; PMCID: PMC3747845.
    37. Araz MK, Tentori AM, Herr A. Microfluidic multiplexing in bioanalyses. J Lab Autom. 2013 Oct; 18(5):350-66. PMID: 23757343.
      View in: PubMed
    38. Duncombe TA, Herr A. Photopatterned free-standing polyacrylamide gels for microfluidic protein electrophoresis. Lab Chip. 2013 Jun 07; 13(11):2115-23. PMID: 23609800.
      View in: PubMed
    39. Tentori AM, Hughes AJ, Herr A. Microchamber integration unifies distinct separation modes for two-dimensional electrophoresis. Anal Chem. 2013 May 07; 85(9):4538-45. PMID: 23565932; PMCID: PMC3714212.
    40. Tia SQ, Brown K, Chen D, Herr A. Protein post-translational modification analyses using on-chip immunoprobed isoelectric focusing. Anal Chem. 2013 Mar 05; 85(5):2882-90. PMID: 23363036.
      View in: PubMed
    41. Apori AA, Brozynski MN, El-Sayed IH, Herr A. Microfluidic validation of diagnostic protein markers for spontaneous cerebrospinal fluid rhinorrhea. J Proteome Res. 2013 Mar 01; 12(3):1254-65. PMID: 23343621.
      View in: PubMed
    42. Karns K, Vogan JM, Qin Q, Hickey SF, Wilson SC, Hammond MC, Herr A. Microfluidic screening of electrophoretic mobility shifts elucidates riboswitch binding function. J Am Chem Soc. 2013 Feb 27; 135(8):3136-43. PMID: 23343213; PMCID: PMC3644558.
    43. Apori AA, Herr A. Chip-based immunoassays. Methods Mol Biol. 2013; 919:233-48. PMID: 22976105.
      View in: PubMed
    44. Hughes AJ, Herr A. Microfluidic Western blotting. Proc Natl Acad Sci U S A. 2012 Dec 26; 109(52):21450-5. PMID: 23223527; PMCID: PMC3535594.
    45. Wheeler AR, Herr A. Mission impossible to mission control. Lab Chip. 2012 Oct 21; 12(20):3851-2. PMID: 22960855.
      View in: PubMed
    46. Hughes AJ, Tentori AM, Herr A. Bistable isoelectric point photoswitching in green fluorescent proteins observed by dynamic immunoprobed isoelectric focusing. J Am Chem Soc. 2012 Oct 24; 134(42):17582-91. PMID: 23017083; PMCID: PMC3488114.
    47. Hou C, Herr A. Microfluidic integration of Western blotting is enabled by electrotransfer-assisted sodium dodecyl sulfate dilution. Analyst. 2013 Jan 07; 138(1):158-63. PMID: 23042290.
      View in: PubMed
    48. Duncombe TA, Herr A. Use of polyacrylamide gel moving boundary electrophoresis to enable low-power protein analysis in a compact microdevice. Anal Chem. 2012 Oct 16; 84(20):8740-7. PMID: 22971048.
      View in: PubMed
    49. Denisin AK, Karns K, Herr A. Post-collection processing of Schirmer strip-collected human tear fluid impacts protein content. Analyst. 2012 Nov 07; 137(21):5088-96. PMID: 22991688.
      View in: PubMed
    50. Hughes AJ, Lin RK, Peehl DM, Herr A. Microfluidic integration for automated targeted proteomic assays. Proc Natl Acad Sci U S A. 2012 Apr 17; 109(16):5972-7. PMID: 22474344; PMCID: PMC3341062.
    51. Kim D, Karns K, Tia SQ, He M, Herr A. Electrostatic protein immobilization using charged polyacrylamide gels and cationic detergent microfluidic Western blotting. Anal Chem. 2012 Mar 06; 84(5):2533-40. PMID: 22304398.
      View in: PubMed
    52. He M, Novak J, Julian BA, Herr A. Membrane-assisted online renaturation for automated microfluidic lectin blotting. J Am Chem Soc. 2011 Dec 14; 133(49):19610-3. PMID: 22070432; PMCID: PMC3267544.
    53. Karns K, Herr A. Microfluidic homo- and hetero-geneous immunoassays: a tool to accelerate protein biomarker development. Bioanalysis. 2011 Oct; 3(19):2161-5. PMID: 21985410.
      View in: PubMed
    54. Karns K, Herr A. Human tear protein analysis enabled by an alkaline microfluidic homogeneous immunoassay. Anal Chem. 2011 Nov 01; 83(21):8115-22. PMID: 21910436.
      View in: PubMed
    55. Chen X, Kapil MA, Hughes AJ, Herr A. Single-microchannel, multistep assay reports protein size and immunoaffinity. Anal Chem. 2011 Sep 01; 83(17):6573-9. PMID: 21834519.
      View in: PubMed
    56. Tentori AM, Herr A. Photopatterned materials in bioanalytical microfluidic technology. J Micromech Microeng. 2011 May 01; 21(5):54001. PMID: 21857772.
      View in: PubMed
    57. Tia SQ, He M, Kim D, Herr A. Multianalyte on-chip native Western blotting. Anal Chem. 2011 May 01; 83(9):3581-8. PMID: 21456518.
      View in: PubMed
    58. Apori AA, Herr A. Homogeneous immunosubtraction integrated with sample preparation enabled by a microfluidic format. Anal Chem. 2011 Apr 01; 83(7):2691-8. PMID: 21375345; PMCID: PMC3069757.
    59. He M, Herr A. Automated microfluidic protein immunoblotting. Nat Protoc. 2010 Nov; 5(11):1844-56. PMID: 21030959.
      View in: PubMed
    60. Wheeler A, Herr A. Intimidating yet inspiring: emerging investigators special issue. Lab Chip. 2010 Sep 21; 10(18):2321-2. PMID: 20730140.
      View in: PubMed
    61. Hughes AJ, Herr A. Quantitative enzyme activity determination with zeptomole sensitivity by microfluidic gradient-gel zymography. Anal Chem. 2010 May 01; 82(9):3803-11. PMID: 20353191.
      View in: PubMed
    62. Hou C, Herr A. Ultrashort separation length homogeneous electrophoretic immunoassays using on-chip discontinuous polyacrylamide gels. Anal Chem. 2010 Apr 15; 82(8):3343-51. PMID: 20334346.
      View in: PubMed
    63. He M, Herr A. Polyacrylamide gel photopatterning enables automated protein immunoblotting in a two-dimensional microdevice. J Am Chem Soc. 2010 Mar 03; 132(8):2512-3. PMID: 20131779.
      View in: PubMed
    64. He M, Herr A. Microfluidic polyacrylamide gel electrophoresis with in situ immunoblotting for native protein analysis. Anal Chem. 2009 Oct 01; 81(19):8177-84. PMID: 19731927.
      View in: PubMed
    65. Srivastava N, Brennan JS, Renzi RF, Wu M, Branda SS, Singh AK, Herr A. Fully integrated microfluidic platform enabling automated phosphoprofiling of macrophage response. Anal Chem. 2009 May 01; 81(9):3261-9. PMID: 19323537.
      View in: PubMed
    66. Tia S, Herr A. On-chip technologies for multidimensional separations. Lab Chip. 2009 Sep 07; 9(17):2524-36. PMID: 19680577.
      View in: PubMed
    67. Ramseier CA, Kinney JS, Herr A, Braun T, Sugai JV, Shelburne CA, Rayburn LA, Tran HM, Singh AK, Giannobile WV. Identification of pathogen and host-response markers correlated with periodontal disease. J Periodontol. 2009 Mar; 80(3):436-46. PMID: 19254128.
      View in: PubMed
    68. Hou C, Herr A. Clinically relevant advances in on-chip affinity-based electrophoresis and electrochromatography. Electrophoresis. 2008 Aug; 29(16):3306-19. PMID: 18702056.
      View in: PubMed
    69. Lo CT, Throckmorton DJ, Singh AK, Herr A. Photopolymerized diffusion-defined polyacrylamide gradient gels for on-chip protein sizing. Lab Chip. 2008 Aug; 8(8):1273-9. PMID: 18651068.
      View in: PubMed
    70. Herr A, Hatch AV, Throckmorton DJ, Tran HM, Brennan JS, Giannobile WV, Singh AK. Microfluidic immunoassays as rapid saliva-based clinical diagnostics. Proc Natl Acad Sci U S A. 2007 Mar 27; 104(13):5268-73. PMID: 17374724; PMCID: PMC1828942.
    71. Herr A, Hatch AV, Giannobile WV, Throckmorton DJ, Tran HM, Brennan JS, Singh AK. Integrated microfluidic platform for oral diagnostics. Ann N Y Acad Sci. 2007 Mar; 1098:362-74. PMID: 17435142; PMCID: PMC2572166.
    72. Hatch AV, Herr A, Throckmorton DJ, Brennan JS, Singh AK. Integrated preconcentration SDS-PAGE of proteins in microchips using photopatterned cross-linked polyacrylamide gels. Anal Chem. 2006 Jul 15; 78(14):4976-84. PMID: 16841920.
      View in: PubMed
    73. Rucker VC, Havenstrite KL, Simmons BA, Sickafoose SM, Herr A, Shediac R. Functional antibody immobilization on 3-dimensional polymeric surfaces generated by reactive ion etching. Langmuir. 2005 Aug 16; 21(17):7621-5. PMID: 16089360.
      View in: PubMed
    74. Rucker VC, Havenstrite KL, Herr A. Antibody microarrays for native toxin detection. Anal Biochem. 2005 Apr 15; 339(2):262-70. PMID: 15797567.
      View in: PubMed
    75. Herr A, Throckmorton DJ, Davenport AA, Singh AK. On-chip native gel electrophoresis-based immunoassays for tetanus antibody and toxin. Anal Chem. 2005 Jan 15; 77(2):585-90. PMID: 15649057.
      View in: PubMed
    76. Herr A, Singh AK. Photopolymerized cross-linked polyacrylamide gels for on-chip protein sizing. Anal Chem. 2004 Aug 15; 76(16):4727-33. PMID: 15307783.
      View in: PubMed
    77. Herr A, Molho JI, Drouvalakis KA, Mikkelsen JC, Utz PJ, Santiago JG, Kenny TW. On-chip coupling of isoelectric focusing and free solution electrophoresis for multidimensional separations. Anal Chem. 2003 Mar 01; 75(5):1180-7. PMID: 12641239.
      View in: PubMed

    This site is running Profiles RNS version v2.10.1-576-g789c7b32 on PROFILES-PWEB02.