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    22833 Publications
    3073 Total Profiles
    24 Edited Profiles

    Northen, Trent

    TitleChemist Staff Sci/Engr
    SchoolLawrence Berkeley National Lab
    DepartmentLife Sciences
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/486-5240

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can sign in to make corrections and additions, or contact us for help.
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      1. Deng K, Guenther JM, Gao J, Bowen BP, Tran H, Reyes-Ortiz V, Cheng X, Sathitsuksanoh N, Heins R, Takasuka TE, Bergeman LF, Geertz-Hansen H, Deutsch S, Loqué D, Sale KL, Simmons BA, Adams PD, Singh AK, Fox BG, Northen TR. Development of a High Throughput Platform for Screening Glycoside Hydrolases Based on Oxime-NIMS. Front Bioeng Biotechnol. 2015; 3:153.
        View in: PubMed
      2. Baran R, Brodie EL, Mayberry-Lewis J, Hummel E, Da Rocha UN, Chakraborty R, Bowen BP, Karaoz U, Cadillo-Quiroz H, Garcia-Pichel F, Northen TR. Exometabolite niche partitioning among sympatric soil bacteria. Nat Commun. 2015; 6:8289.
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      3. Yao Y, Sun T, Wang T, Ruebel O, Northen T, Bowen BP. Analysis of Metabolomics Datasets with High-Performance Computing and Metabolite Atlases. Metabolites. 2015; 5(3):431-42.
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      4. Ceja-Navarro JA, Vega FE, Karaoz U, Hao Z, Jenkins S, Lim HC, Kosina P, Infante F, Northen TR, Brodie EL. Gut microbiota mediate caffeine detoxification in the primary insect pest of coffee. Nat Commun. 2015; 6:7618.
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      5. Miquel S, Leclerc M, Martin R, Chain F, Lenoir M, Raguideau S, Hudault S, Bridonneau C, Northen T, Bowen B, Bermúdez-Humarán LG, Sokol H, Thomas M, Langella P. Identification of Metabolic Signatures Linked to Anti-Inflammatory Effects of Faecalibacterium prausnitzii. MBio. 2015; 6(2).
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      6. Nunes da Rocha U, Cadillo-Quiroz H, Karaoz U, Rajeev L, Klitgord N, Dunn S, Truong V, Buenrostro M, Bowen BP, Garcia-Pichel F, Mukhopadhyay A, Northen TR, Brodie EL. Isolation of a significant fraction of non-phototroph diversity from a desert Biological Soil Crust. Front Microbiol. 2015; 6:277.
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      7. Silva LP, Northen TR. Exometabolomics and MSI: deconstructing how cells interact to transform their small molecule environment. Curr Opin Biotechnol. 2015 Aug; 34:209-16.
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      8. Castellanos-Martín A, Castillo-Lluva S, Sáez-Freire Mdel M, Blanco-Gómez A, Hontecillas-Prieto L, Patino-Alonso C, Galindo-Villardon P, Pérez Del Villar L, Martín-Seisdedos C, Isidoro-Garcia M, Abad-Hernández Mdel M, Cruz-Hernández JJ, Rodríguez-Sánchez CA, González-Sarmiento R, Alonso-López D, De Las Rivas J, García-Cenador B, García-Criado J, Lee do Y, Bowen B, Reindl W, Northen T, Mao JH, Pérez-Losada J. Unraveling heterogeneous susceptibility and the evolution of breast cancer using a systems biology approach. Genome Biol. 2015; 16(1):40.
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      9. Kurczy ME, Northen TR, Trauger SA, Siuzdak G. Nanostructure imaging mass spectrometry: the role of fluorocarbons in metabolite analysis and yoctomole level sensitivity. Methods Mol Biol. 2015; 1203:141-9.
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      10. Berleman JE, Allen S, Danielewicz MA, Remis JP, Gorur A, Cunha J, Hadi MZ, Zusman DR, Northen TR, Witkowska HE, Auer M. The lethal cargo of Myxococcus xanthus outer membrane vesicles. Front Microbiol. 2014; 5:474.
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      11. de Rond T, Danielewicz M, Northen T. High throughput screening of enzyme activity with mass spectrometry imaging. Curr Opin Biotechnol. 2015 Feb; 31:1-9.
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      12. Heins RA, Cheng X, Nath S, Deng K, Bowen BP, Chivian DC, Datta S, Friedland GD, D'Haeseleer P, Wu D, Tran-Gyamfi M, Scullin CS, Singh S, Shi W, Hamilton MG, Bendall ML, Sczyrba A, Thompson J, Feldman T, Guenther JM, Gladden JM, Cheng JF, Adams PD, Rubin EM, Simmons BA, Sale KL, Northen TR, Deutsch S. Phylogenomically Guided Identification of Industrially Relevant GH1 ß-Glucosidases through DNA Synthesis and Nanostructure-Initiator Mass Spectrometry. ACS Chem Biol. 2014 Sep 19; 9(9):2082-91.
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      13. Deng K, Takasuka TE, Heins R, Cheng X, Bergeman LF, Shi J, Aschenbrener R, Deutsch S, Singh S, Sale KL, Simmons BA, Adams PD, Singh AK, Fox BG, Northen TR. Rapid Kinetic Characterization of Glycosyl Hydrolases Based on Oxime Derivatization and Nanostructure-Initiator Mass Spectrometry (NIMS). ACS Chem Biol. 2014 Jul 18; 9(7):1470-9.
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      14. Louie KB, Northen TR. Metabolic Imaging Using Nanostructure-Initiator Mass Spectrometry (NIMS). Methods Mol Biol. 2014; 1198:313-29.
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      15. Cheng X, Hiras J, Deng K, Bowen B, Simmons BA, Adams PD, Singer SW, Northen TR. High throughput nanostructure-initiator mass spectrometry screening of microbial growth conditions for maximal ß-glucosidase production. Front Microbiol. 2013; 4:365.
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      16. Louie KB, Bowen BP, Cheng X, Berleman JE, Chakraborty R, Deutschbauer A, Arkin A, Northen TR. "Replica-extraction-transfer" nanostructure-initiator mass spectrometry imaging of acoustically printed bacteria. Anal Chem. 2013 Nov 19; 85(22):10856-62.
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      17. Rübel O, Greiner A, Cholia S, Louie K, Bethel EW, Northen TR, Bowen BP. OpenMSI: A High-Performance Web-Based Platform for Mass Spectrometry Imaging. Anal Chem. 2013 Nov 5; 85(21):10354-61.
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      18. Baran R, Ivanova NN, Jose N, Garcia-Pichel F, Kyrpides NC, Gugger M, Northen TR. Functional genomics of novel secondary metabolites from diverse cyanobacteria using untargeted metabolomics. Mar Drugs. 2013; 11(10):3617-31.
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      19. Baran R, Northen TR. Robust automated mass spectra interpretation and chemical formula calculation using mixed integer linear programming. Anal Chem. 2013 Oct 15; 85(20):9777-84.
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      20. Rajeev L, da Rocha UN, Klitgord N, Luning EG, Fortney J, Axen SD, Shih PM, Bouskill NJ, Bowen BP, Kerfeld CA, Garcia-Pichel F, Brodie EL, Northen TR, Mukhopadhyay A. Dynamic cyanobacterial response to hydration and dehydration in a desert biological soil crust. ISME J. 2013 Nov; 7(11):2178-91.
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      21. Fischer CR, Bowen BP, Pan C, Northen TR, Banfield JF. Stable-isotope probing reveals that hydrogen isotope fractionation in proteins and lipids in a microbial community are different and species-specific. ACS Chem Biol. 2013 Aug 16; 8(8):1755-63.
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      22. Ho JC, Storm P, Rydström A, Bowen B, Alsin F, Sullivan L, Ambite I, Mok KH, Northen T, Svanborg C. Lipids as tumoricidal components of human a-lactalbumin made lethal to tumor cells (HAMLET): unique and shared effects on signaling and death. J Biol Chem. 2013 Jun 14; 288(24):17460-71.
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      23. McAndrew RP, Park JI, Heins RA, Reindl W, Friedland GD, D'haeseleer P, Northen T, Sale KL, Simmons BA, Adams PD. From soil to structure, a novel dimeric ß-glucosidase belonging to glycoside hydrolase family 3 isolated from compost using metagenomic analysis. J Biol Chem. 2013 May 24; 288(21):14985-92.
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      24. de Rond T, Peralta-Yahya P, Cheng X, Northen TR, Keasling JD. Versatile synthesis of probes for high-throughput enzyme activity screening. Anal Bioanal Chem. 2013 May; 405(14):4969-73.
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      25. Mosier AC, Justice NB, Bowen BP, Baran R, Thomas BC, Northen TR, Banfield JF. Metabolites associated with adaptation of microorganisms to an acidophilic, metal-rich environment identified by stable-isotope-enabled metabolomics. MBio. 2013; 4(2):e00484-12.
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      26. Louie KB, Bowen BP, McAlhany S, Huang Y, Price JC, Mao JH, Hellerstein M, Northen TR. Mass spectrometry imaging for in situ kinetic histochemistry. Sci Rep. 2013; 3:1656.
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      27. Baran R, Bowen BP, Price MN, Arkin AP, Deutschbauer AM, Northen TR. Metabolic footprinting of mutant libraries to map metabolite utilization to genotype. ACS Chem Biol. 2013 Jan 18; 8(1):189-99.
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      28. Lee do Y, Bowen BP, Nguyen DH, Parsa S, Huang Y, Mao JH, Northen TR. Low-dose ionizing radiation-induced blood plasma metabolic response in a diverse genetic mouse population. Radiat Res. 2012 Dec; 178(6):551-5.
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      29. Lee do Y, Platt V, Bowen B, Louie K, Canaria CA, McMurray CT, Northen T. Resolving brain regions using nanostructure initiator mass spectrometry imaging of phospholipids. Integr Biol (Camb). 2012 Jun; 4(6):693-9.
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      30. Deng K, George KW, Reindl W, Keasling JD, Adams PD, Lee TS, Singh AK, Northen TR. Encoding substrates with mass tags to resolve stereospecific reactions using Nimzyme. Rapid Commun Mass Spectrom. 2012 Mar 30; 26(6):611-5.
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      31. Greving M, Cheng X, Reindl W, Bowen B, Deng K, Louie K, Nyman M, Cohen J, Singh A, Simmons B, Adams P, Siuzdak G, Northen T. Acoustic deposition with NIMS as a high-throughput enzyme activity assay. Anal Bioanal Chem. 2012 May; 403(3):707-11.
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      32. Baran R, Bowen BP, Northen TR. Untargeted metabolic footprinting reveals a surprising breadth of metabolite uptake and release by Synechococcus sp. PCC 7002. Mol Biosyst. 2011 Dec; 7(12):3200-6.
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      33. Bowen BP, Fischer CR, Baran R, Banfield JF, Northen T. Improved genome annotation through untargeted detection of pathway-specific metabolites. BMC Genomics. 2011; 12 Suppl 1:S6.
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      34. Storm P, Aits S, Puthia MK, Urbano A, Northen T, Powers S, Bowen B, Chao Y, Reindl W, Lee DY, Sullivan NL, Zhang J, Trulsson M, Yang H, Watson JD, Svanborg C. Conserved features of cancer cells define their sensitivity to HAMLET-induced death; c-Myc and glycolysis. Oncogene. 2011 Dec 1; 30(48):4765-79.
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      35. Reindl W, Bowen BP, Balamotis MA, Green JE, Northen TR. Multivariate analysis of a 3D mass spectral image for examining tissue heterogeneity. Integr Biol (Camb). 2011 Apr; 3(4):460-7.
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      36. Wilmes P, Bowen BP, Thomas BC, Mueller RS, Denef VJ, VerBerkmoes NC, Hettich RL, Northen TR, Banfield JF. Metabolome-proteome differentiation coupled to microbial divergence. MBio. 2010; 1(5).
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      37. Baran R, Bowen BP, Bouskill NJ, Brodie EL, Yannone SM, Northen TR. Metabolite identification in Synechococcus sp. PCC 7002 using untargeted stable isotope assisted metabolite profiling. Anal Chem. 2010 Nov 1; 82(21):9034-42.
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      38. Lee DY, Bowen BP, Northen TR. Mass spectrometry-based metabolomics, analysis of metabolite-protein interactions, and imaging. Biotechniques. 2010 Aug; 49(2):557-65.
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      39. Facciotti MT, Pang WL, Lo FY, Whitehead K, Koide T, Masumura K, Pan M, Kaur A, Larsen DJ, Reiss DJ, Hoang L, Kalisiak E, Northen T, Trauger SA, Siuzdak G, Baliga NS. Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. BMC Syst Biol. 2010; 4:64.
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      40. Reindl W, Northen TR. Rapid screening of fatty acids using nanostructure-initiator mass spectrometry. Anal Chem. 2010 May 1; 82(9):3751-5.
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      41. Jansson C, Northen T. Calcifying cyanobacteria--the potential of biomineralization for carbon capture and storage. Curr Opin Biotechnol. 2010 Jun; 21(3):365-71.
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      42. Bowen BP, Northen TR. Dealing with the unknown: metabolomics and metabolite atlases. J Am Soc Mass Spectrom. 2010 Sep; 21(9):1471-6.
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      43. Baran R, Reindl W, Northen TR. Mass spectrometry based metabolomics and enzymatic assays for functional genomics. Curr Opin Microbiol. 2009 Oct; 12(5):547-52.
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      44. Woo HK, Go EP, Hoang L, Trauger SA, Bowen B, Siuzdak G, Northen TR. Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2009 Jun; 23(12):1849-55.
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      45. Yanes O, Woo HK, Northen TR, Oppenheimer SR, Shriver L, Apon J, Estrada MN, Potchoiba MJ, Steenwyk R, Manchester M, Siuzdak G. Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis. Anal Chem. 2009 Apr 15; 81(8):2969-75.
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      46. Northen TR, Lee JC, Hoang L, Raymond J, Hwang DR, Yannone SM, Wong CH, Siuzdak G. A nanostructure-initiator mass spectrometry-based enzyme activity assay. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3678-83.
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      47. Woo HK, Northen TR, Yanes O, Siuzdak G. Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis. Nat Protoc. 2008; 3(8):1341-9.
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      48. Nordström A, Want E, Northen T, Lehtiö J, Siuzdak G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics. Anal Chem. 2008 Jan 15; 80(2):421-9.
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      49. Northen TR, Yanes O, Northen MT, Marrinucci D, Uritboonthai W, Apon J, Golledge SL, Nordström A, Siuzdak G. Clathrate nanostructures for mass spectrometry. Nature. 2007 Oct 25; 449(7165):1033-6.
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      50. Northen TR, Woo HK, Northen MT, Nordström A, Uritboonthail W, Turner KL, Siuzdak G. High surface area of porous silicon drives desorption of intact molecules. J Am Soc Mass Spectrom. 2007 Nov; 18(11):1945-9.
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      51. Northen TR, Brune DC, Woodbury NW. Synthesis and characterization of peptide grafted porous polymer microstructures. Biomacromolecules. 2006 Mar; 7(3):750-4.
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      52. Northen TR, Woodbury NW. Light-directed movement of polymer microstructures. Langmuir. 2005 May 24; 21(11):4949-53.
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