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    22833 Publications
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    Siuzdak, Gary

    TitleVisiting Faculty Non-UC
    SchoolLawrence Berkeley National Lab
    DepartmentLife Sciences
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/495-2404

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can sign in to make corrections and additions, or contact us for help.
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      1. Fang M, Ivanisevic J, Benton HP, Johnson CH, Patti GJ, Hoang LT, Uritboonthai W, Kurczy ME, Siuzdak G. Thermal Degradation of Small Molecules: A Global Metabolomic Investigation. Anal Chem. 2015 Nov 3; 87(21):10935-41.
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      2. Kurczy ME, Ivanisevic J, Johnson CH, Uritboonthai W, Hoang L, Fang M, Hicks M, Aldebot A, Rinehart D, Mellander LJ, Tautenhahn R, Patti GJ, Spilker ME, Benton HP, Siuzdak G. Determining conserved metabolic biomarkers from a million database queries. Bioinformatics. 2015 Dec 1; 31(23):3721-4.
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      3. Ivanisevic J, Elias D, Deguchi H, Averell PM, Kurczy M, Johnson CH, Tautenhahn R, Zhu Z, Watrous J, Jain M, Griffin J, Patti GJ, Siuzdak G. Arteriovenous Blood Metabolomics: A Readout of Intra-Tissue Metabostasis. Sci Rep. 2015; 5:12757.
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      4. Johnson CH, Patti GJ, Courade JP, Shriver LP, Hoang LT, Manchester M, Siuzdak G. Alterations in Spinal Cord Metabolism during Treatment of Neuropathic Pain. J Neuroimmune Pharmacol. 2015 Sep; 10(3):396-401.
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      5. Ivanisevic J, Siuzdak G. The Role of Metabolomics in Brain Metabolism Research. J Neuroimmune Pharmacol. 2015 Sep; 10(3):391-5.
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      6. Deguchi H, Banerjee Y, Trauger S, Siuzdak G, Kalisiak E, Fernández JA, Hoang L, Tran M, Yegneswaran S, Elias DJ, Griffin JH. Acylcarnitines are anticoagulants that inhibit factor Xa and are reduced in venous thrombosis, based on metabolomics data. Blood. 2015 Sep 24; 126(13):1595-600.
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      7. Johnson CH, Dejea CM, Edler D, Hoang LT, Santidrian AF, Felding BH, Ivanisevic J, Cho K, Wick EC, Hechenbleikner EM, Uritboonthai W, Goetz L, Casero RA, Pardoll DM, White JR, Patti GJ, Sears CL, Siuzdak G. Metabolism links bacterial biofilms and colon carcinogenesis. Cell Metab. 2015 Jun 2; 21(6):891-7.
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      8. Nikolskiy I, Siuzdak G, Patti GJ. Discriminating precursors of common fragments for large-scale metabolite profiling by triple quadrupole mass spectrometry. Bioinformatics. 2015 Jun 15; 31(12):2017-23.
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      9. Kurczy ME, Zhu ZJ, Ivanisevic J, Schuyler AM, Lalwani K, Santidrian AF, David JM, Giddabasappa A, Roberts AJ, Olivos HJ, O'Brien PJ, Franco L, Fields MW, Paris LP, Friedlander M, Johnson CH, Epstein AA, Gendelman HE, Wood MR, Felding BH, Patti GJ, Spilker ME, Siuzdak G. Comprehensive bioimaging with fluorinated nanoparticles using breathable liquids. Nat Commun. 2015; 6:5998.
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      10. Kurczy ME, Northen TR, Trauger SA, Siuzdak G. Nanostructure imaging mass spectrometry: the role of fluorocarbons in metabolite analysis and yoctomole level sensitivity. Methods Mol Biol. 2015; 1203:141-9.
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      11. Benton HP, Ivanisevic J, Mahieu NG, Kurczy ME, Johnson CH, Franco L, Rinehart D, Valentine E, Gowda H, Ubhi BK, Tautenhahn R, Gieschen A, Fields MW, Patti GJ, Siuzdak G. Autonomous metabolomics for rapid metabolite identification in global profiling. Anal Chem. 2015 Jan 20; 87(2):884-91.
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      12. Johnson CH, Ivanisevic J, Benton HP, Siuzdak G. Bioinformatics: the next frontier of metabolomics. Anal Chem. 2015 Jan 6; 87(1):147-56.
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      13. Ivanisevic J, Epstein AA, Kurczy ME, Benton PH, Uritboonthai W, Fox HS, Boska MD, Gendelman HE, Siuzdak G. Brain region mapping using global metabolomics. Chem Biol. 2014 Nov 20; 21(11):1575-84.
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      14. Cho K, Mahieu N, Ivanisevic J, Uritboonthai W, Chen YJ, Siuzdak G, Patti GJ. isoMETLIN: A Database for Isotope-Based Metabolomics. Anal Chem. 2014 Oct 7; 86(19):9358-61.
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      15. Gowda H, Ivanisevic J, Johnson CH, Kurczy ME, Benton HP, Rinehart D, Nguyen T, Ray J, Kuehl J, Arevalo B, Westenskow PD, Wang J, Arkin AP, Deutschbauer AM, Patti GJ, Siuzdak G. Interactive XCMS Online: Simplifying Advanced Metabolomic Data Processing and Subsequent Statistical Analyses. Anal Chem. 2014 Jul 15; 86(14):6931-9.
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      16. Rinehart D, Johnson CH, Nguyen T, Ivanisevic J, Benton HP, Lloyd J, Arkin AP, Deutschbauer AM, Patti GJ, Siuzdak G. Metabolomic data streaming for biology-dependent data acquisition. Nat Biotechnol. 2014 Jun 9; 32(6):524-7.
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      17. Deguchi H, Elias DJ, Trauger S, Zhang HM, Kalisiak E, Siuzdak G, Griffin JH. Warfarin untargeted metabolomics study identifies novel procoagulant ethanolamide plasma lipids. Br J Haematol. 2014 May; 165(3):409-12.
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      18. Ivanisevic J, Zhu ZJ, Plate L, Tautenhahn R, Chen S, O'Brien PJ, Johnson CH, Marletta MA, Patti GJ, Siuzdak G. Toward 'omic scale metabolite profiling: a dual separation-mass spectrometry approach for coverage of lipid and central carbon metabolism. Anal Chem. 2013 Jul 16; 85(14):6876-84.
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      19. Zhu ZJ, Schultz AW, Wang J, Johnson CH, Yannone SM, Patti GJ, Siuzdak G. Liquid chromatography quadrupole time-of-flight mass spectrometry characterization of metabolites guided by the METLIN database. Nat Protoc. 2013 Mar; 8(3):451-60.
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      20. O'Brien PJ, Lee M, Spilker ME, Zhang CC, Yan Z, Nichols TC, Li W, Johnson CH, Patti GJ, Siuzdak G. Monitoring metabolic responses to chemotherapy in single cells and tumors using nanostructure-initiator mass spectrometry (NIMS) imaging. Cancer Metab. 2013; 1(1):4.
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      21. Blankman JL, Long JZ, Trauger SA, Siuzdak G, Cravatt BF. ABHD12 controls brain lysophosphatidylserine pathways that are deregulated in a murine model of the neurodegenerative disease PHARC. Proc Natl Acad Sci U S A. 2013 Jan 22; 110(4):1500-5.
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      22. Patti GJ, Tautenhahn R, Rinehart D, Cho K, Shriver LP, Manchester M, Nikolskiy I, Johnson CH, Mahieu NG, Siuzdak G. A view from above: cloud plots to visualize global metabolomic data. Anal Chem. 2013 Jan 15; 85(2):798-804.
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      23. Tautenhahn R, Cho K, Uritboonthai W, Zhu Z, Patti GJ, Siuzdak G. An accelerated workflow for untargeted metabolomics using the METLIN database. Nat Biotechnol. 2012 Sep; 30(9):826-8.
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      24. Tautenhahn R, Patti GJ, Rinehart D, Siuzdak G. XCMS Online: a web-based platform to process untargeted metabolomic data. Anal Chem. 2012 Jun 5; 84(11):5035-9.
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      25. Patti GJ, Yanes O, Siuzdak G. Innovation: Metabolomics: the apogee of the omics trilogy. Nat Rev Mol Cell Biol. 2012 Apr; 13(4):263-9.
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      26. Greving M, Cheng X, Reindl W, Bowen B, Deng K, Louie K, Nyman M, Cohen J, Singh A, Simmons B, Adams P, Siuzdak G, Northen T. Acoustic deposition with NIMS as a high-throughput enzyme activity assay. Anal Bioanal Chem. 2012 May; 403(3):707-11.
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      27. Patti GJ, Tautenhahn R, Siuzdak G. Meta-analysis of untargeted metabolomic data from multiple profiling experiments. Nat Protoc. 2012 Mar; 7(3):508-16.
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      28. Ukrohne TU, Westenskow PD, Kurihara T, Friedlander DF, Lehmann M, Dorsey AL, Li W, Zhu S, Schultz A, Wang J, Siuzdak G, Ding S, Friedlander M. Generation of retinal pigment epithelial cells from small molecules and OCT4 reprogrammed human induced pluripotent stem cells. Stem Cells Transl Med. 2012 Feb; 1(2):96-109.
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      29. Patti GJ, Yanes O, Shriver LP, Courade JP, Tautenhahn R, Manchester M, Siuzdak G. Metabolomics implicates altered sphingolipids in chronic pain of neuropathic origin. Nat Chem Biol. 2012 Mar; 8(3):232-4.
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      30. Panopoulos AD, Yanes O, Ruiz S, Kida YS, Diep D, Tautenhahn R, Herrerías A, Batchelder EM, Plongthongkum N, Lutz M, Berggren WT, Zhang K, Evans RM, Siuzdak G, Izpisua Belmonte JC. The metabolome of induced pluripotent stem cells reveals metabolic changes occurring in somatic cell reprogramming. Cell Res. 2012 Jan; 22(1):168-77.
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      31. Long JZ, Cisar JS, Milliken D, Niessen S, Wang C, Trauger SA, Siuzdak G, Cravatt BF. Metabolomics annotates ABHD3 as a physiologic regulator of medium-chain phospholipids. Nat Chem Biol. 2011 Nov; 7(11):763-5.
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      32. Marchetti V, Yanes O, Aguilar E, Wang M, Friedlander D, Moreno S, Storm K, Zhan M, Naccache S, Nemerow G, Siuzdak G, Friedlander M. Differential macrophage polarization promotes tissue remodeling and repair in a model of ischemic retinopathy. Sci Rep. 2011; 1:76.
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      33. Lancaster WA, Praissman JL, Poole FL, Cvetkovic A, Menon AL, Scott JW, Jenney FE, Thorgersen MP, Kalisiak E, Apon JV, Trauger SA, Siuzdak G, Tainer JA, Adams MW. A computational framework for proteome-wide pursuit and prediction of metalloproteins using ICP-MS and MS/MS data. BMC Bioinformatics. 2011; 12:64.
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      34. Yanes O, Tautenhahn R, Patti GJ, Siuzdak G. Expanding coverage of the metabolome for global metabolite profiling. Anal Chem. 2011 Mar 15; 83(6):2152-61.
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      35. Tautenhahn R, Patti GJ, Kalisiak E, Miyamoto T, Schmidt M, Lo FY, McBee J, Baliga NS, Siuzdak G. metaXCMS: second-order analysis of untargeted metabolomics data. Anal Chem. 2011 Feb 1; 83(3):696-700.
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      36. Powers ME, Smith PA, Roberts TC, Fowler BJ, King CC, Trauger SA, Siuzdak G, Romesberg FE. Type I signal peptidase and protein secretion in Staphylococcus epidermidis. J Bacteriol. 2011 Jan; 193(2):340-8.
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      37. Greving MP, Patti GJ, Siuzdak G. Nanostructure-initiator mass spectrometry metabolite analysis and imaging. Anal Chem. 2011 Jan 1; 83(1):2-7.
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      38. Pendyala G, Trauger SA, Siuzdak G, Fox HS. Short communication: quantitative proteomic plasma profiling reveals activation of host defense to oxidative stress in chronic SIV and methamphetamine comorbidity. AIDS Res Hum Retroviruses. 2011 Feb; 27(2):179-82.
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      39. Kopp F, Komatsu T, Nomura DK, Trauger SA, Thomas JR, Siuzdak G, Simon GM, Cravatt BF. The glycerophospho metabolome and its influence on amino acid homeostasis revealed by brain metabolomics of GDE1(-/-) mice. Chem Biol. 2010 Aug 27; 17(8):831-40.
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      40. Patti GJ, Shriver LP, Wassif CA, Woo HK, Uritboonthai W, Apon J, Manchester M, Porter FD, Siuzdak G. Nanostructure-initiator mass spectrometry (NIMS) imaging of brain cholesterol metabolites in Smith-Lemli-Opitz syndrome. Neuroscience. 2010 Oct 27; 170(3):858-64.
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      41. Cvetkovic A, Menon AL, Thorgersen MP, Scott JW, Poole FL, Jenney FE, Lancaster WA, Praissman JL, Shanmukh S, Vaccaro BJ, Trauger SA, Kalisiak E, Apon JV, Siuzdak G, Yannone SM, Tainer JA, Adams MW. Microbial metalloproteomes are largely uncharacterized. Nature. 2010 Aug 5; 466(7307):779-82.
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      42. Lowe RD, Szili EJ, Kirkbride P, Thissen H, Siuzdak G, Voelcker NH. Combined immunocapture and laser desorption/ionization mass spectrometry on porous silicon. Anal Chem. 2010 May 15; 82(10):4201-8.
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      43. Facciotti MT, Pang WL, Lo FY, Whitehead K, Koide T, Masumura K, Pan M, Kaur A, Larsen DJ, Reiss DJ, Hoang L, Kalisiak E, Northen T, Trauger SA, Siuzdak G, Baliga NS. Large scale physiological readjustment during growth enables rapid, comprehensive and inexpensive systems analysis. BMC Syst Biol. 2010; 4:64.
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      44. Yanes O, Clark J, Wong DM, Patti GJ, Sánchez-Ruiz A, Benton HP, Trauger SA, Desponts C, Ding S, Siuzdak G. Metabolic oxidation regulates embryonic stem cell differentiation. Nat Chem Biol. 2010 Jun; 6(6):411-7.
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      45. Pendyala G, Trauger SA, Siuzdak G, Fox HS. Quantitative plasma proteomic profiling identifies the vitamin E binding protein afamin as a potential pathogenic factor in SIV induced CNS disease. J Proteome Res. 2010 Jan; 9(1):352-8.
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      46. Patti GJ, Woo HK, Yanes O, Shriver L, Thomas D, Uritboonthai W, Apon JV, Steenwyk R, Manchester M, Siuzdak G. Detection of carbohydrates and steroids by cation-enhanced nanostructure-initiator mass spectrometry (NIMS) for biofluid analysis and tissue imaging. Anal Chem. 2010 Jan 1; 82(1):121-8.
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      47. Dorrell MI, Aguilar E, Jacobson R, Trauger SA, Friedlander J, Siuzdak G, Friedlander M. Maintaining retinal astrocytes normalizes revascularization and prevents vascular pathology associated with oxygen-induced retinopathy. Glia. 2010 Jan 1; 58(1):43-54.
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      48. Crews B, Wikoff WR, Patti GJ, Woo HK, Kalisiak E, Heideker J, Siuzdak G. Variability analysis of human plasma and cerebral spinal fluid reveals statistical significance of changes in mass spectrometry-based metabolomics data. Anal Chem. 2009 Oct 15; 81(20):8538-44.
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      49. Wikoff WR, Kalisak E, Trauger S, Manchester M, Siuzdak G. Response and recovery in the plasma metabolome tracks the acute LCMV-induced immune response. J Proteome Res. 2009 Jul; 8(7):3578-87.
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      50. Woo HK, Go EP, Hoang L, Trauger SA, Bowen B, Siuzdak G, Northen TR. Phosphonium labeling for increasing metabolomic coverage of neutral lipids using electrospray ionization mass spectrometry. Rapid Commun Mass Spectrom. 2009 Jun; 23(12):1849-55.
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      51. Koudelka KJ, Destito G, Plummer EM, Trauger SA, Siuzdak G, Manchester M. Endothelial targeting of cowpea mosaic virus (CPMV) via surface vimentin. PLoS Pathog. 2009 May; 5(5):e1000417.
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      52. Pendyala G, Trauger SA, Kalisiak E, Ellis RJ, Siuzdak G, Fox HS. Cerebrospinal fluid proteomics reveals potential pathogenic changes in the brains of SIV-infected monkeys. J Proteome Res. 2009 May; 8(5):2253-60.
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      53. Zhou H, Wu S, Joo JY, Zhu S, Han DW, Lin T, Trauger S, Bien G, Yao S, Zhu Y, Siuzdak G, Schöler HR, Duan L, Ding S. Generation of induced pluripotent stem cells using recombinant proteins. Cell Stem Cell. 2009 May 8; 4(5):381-4.
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      54. Yanes O, Woo HK, Northen TR, Oppenheimer SR, Shriver L, Apon J, Estrada MN, Potchoiba MJ, Steenwyk R, Manchester M, Siuzdak G. Nanostructure initiator mass spectrometry: tissue imaging and direct biofluid analysis. Anal Chem. 2009 Apr 15; 81(8):2969-75.
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      55. Wikoff WR, Anfora AT, Liu J, Schultz PG, Lesley SA, Peters EC, Siuzdak G. Metabolomics analysis reveals large effects of gut microflora on mammalian blood metabolites. Proc Natl Acad Sci U S A. 2009 Mar 10; 106(10):3698-703.
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      56. Dorrell MI, Aguilar E, Jacobson R, Yanes O, Gariano R, Heckenlively J, Banin E, Ramirez GA, Gasmi M, Bird A, Siuzdak G, Friedlander M. Antioxidant or neurotrophic factor treatment preserves function in a mouse model of neovascularization-associated oxidative stress. J Clin Invest. 2009 Mar; 119(3):611-23.
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      57. Kalisiak J, Trauger SA, Kalisiak E, Morita H, Fokin VV, Adams MW, Sharpless KB, Siuzdak G. Identification of a new endogenous metabolite and the characterization of its protein interactions through an immobilization approach. J Am Chem Soc. 2009 Jan 14; 131(1):378-86.
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      58. Bunner AE, Trauger SA, Siuzdak G, Williamson JR. Quantitative ESI-TOF analysis of macromolecular assembly kinetics. Anal Chem. 2008 Dec 15; 80(24):9379-86.
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      59. Menon AL, Poole FL, Cvetkovic A, Trauger SA, Kalisiak E, Scott JW, Shanmukh S, Praissman J, Jenney FE, Wikoff WR, Apon JV, Siuzdak G, Adams MW. Novel multiprotein complexes identified in the hyperthermophilic archaeon Pyrococcus furiosus by non-denaturing fractionation of the native proteome. Mol Cell Proteomics. 2009 Apr; 8(4):735-51.
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      60. Benton HP, Wong DM, Trauger SA, Siuzdak G. XCMS2: processing tandem mass spectrometry data for metabolite identification and structural characterization. Anal Chem. 2008 Aug 15; 80(16):6382-9.
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      61. Wikoff WR, Pendyala G, Siuzdak G, Fox HS. Metabolomic analysis of the cerebrospinal fluid reveals changes in phospholipase expression in the CNS of SIV-infected macaques. J Clin Invest. 2008 Jul; 118(7):2661-9.
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      62. Vallon V, Eraly SA, Wikoff WR, Rieg T, Kaler G, Truong DM, Ahn SY, Mahapatra NR, Mahata SK, Gangoiti JA, Wu W, Barshop BA, Siuzdak G, Nigam SK. Organic anion transporter 3 contributes to the regulation of blood pressure. J Am Soc Nephrol. 2008 Sep; 19(9):1732-40.
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      63. Northen TR, Lee JC, Hoang L, Raymond J, Hwang DR, Yannone SM, Wong CH, Siuzdak G. A nanostructure-initiator mass spectrometry-based enzyme activity assay. Proc Natl Acad Sci U S A. 2008 Mar 11; 105(10):3678-83.
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      64. Eraly SA, Vallon V, Rieg T, Gangoiti JA, Wikoff WR, Siuzdak G, Barshop BA, Nigam SK. Multiple organic anion transporters contribute to net renal excretion of uric acid. Physiol Genomics. 2008 Apr 22; 33(2):180-92.
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      65. Trauger SA, Kalisak E, Kalisiak J, Morita H, Weinberg MV, Menon AL, Poole FL, Adams MW, Siuzdak G. Correlating the transcriptome, proteome, and metabolome in the environmental adaptation of a hyperthermophile. J Proteome Res. 2008 Mar; 7(3):1027-35.
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      66. Woo HK, Northen TR, Yanes O, Siuzdak G. Nanostructure-initiator mass spectrometry: a protocol for preparing and applying NIMS surfaces for high-sensitivity mass analysis. Nat Protoc. 2008; 3(8):1341-9.
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      67. Nordström A, Want E, Northen T, Lehtiö J, Siuzdak G. Multiple ionization mass spectrometry strategy used to reveal the complexity of metabolomics. Anal Chem. 2008 Jan 15; 80(2):421-9.
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      68. Northen TR, Yanes O, Northen MT, Marrinucci D, Uritboonthai W, Apon J, Golledge SL, Nordström A, Siuzdak G. Clathrate nanostructures for mass spectrometry. Nature. 2007 Oct 25; 449(7165):1033-6.
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      69. Wikoff WR, Gangoiti JA, Barshop BA, Siuzdak G. Metabolomics identifies perturbations in human disorders of propionate metabolism. Clin Chem. 2007 Dec; 53(12):2169-76.
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      70. Northen TR, Woo HK, Northen MT, Nordström A, Uritboonthail W, Turner KL, Siuzdak G. High surface area of porous silicon drives desorption of intact molecules. J Am Soc Mass Spectrom. 2007 Nov; 18(11):1945-9.
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      71. Lissauer ME, Johnson SB, Siuzdak G, Bochicchio G, Whiteford C, Nussbaumer B, Moore R, Scalea TM. Coagulation and complement protein differences between septic and uninfected systemic inflammatory response syndrome patients. J Trauma. 2007 May; 62(5):1082-92; discussion 1092-4.
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      72. Go EP, Uritboonthai W, Apon JV, Trauger SA, Nordstrom A, O'Maille G, Brittain SM, Peters EC, Siuzdak G. Selective metabolite and peptide capture/mass detection using fluorous affinity tags. J Proteome Res. 2007 Apr; 6(4):1492-9.
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      73. Want EJ, Nordström A, Morita H, Siuzdak G. From exogenous to endogenous: the inevitable imprint of mass spectrometry in metabolomics. J Proteome Res. 2007 Feb; 6(2):459-68.
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      74. Mutch DM, O'Maille G, Wikoff WR, Wiedmer T, Sims PJ, Siuzdak G. Mobilization of pro-inflammatory lipids in obese Plscr3-deficient mice. Genome Biol. 2007; 8(3):R38.
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      75. Shen Z, Want EJ, Chen W, Keating W, Nussbaumer W, Moore R, Gentle TM, Siuzdak G. Sepsis plasma protein profiling with immunodepletion, three-dimensional liquid chromatography tandem mass spectrometry, and spectrum counting. J Proteome Res. 2006 Nov; 5(11):3154-60.
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      76. Pendyala G, Want EJ, Webb W, Siuzdak G, Fox HS. Biomarkers for neuroAIDS: the widening scope of metabolomics. J Neuroimmune Pharmacol. 2007 Mar; 2(1):72-80.
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      77. Go EP, Wikoff WR, Shen Z, O'Maille G, Morita H, Conrads TP, Nordstrom A, Trauger SA, Uritboonthai W, Lucas DA, Chan KC, Veenstra TD, Lewicki H, Oldstone MB, Schneemann A, Siuzdak G. Mass spectrometry reveals specific and global molecular transformations during viral infection. J Proteome Res. 2006 Sep; 5(9):2405-16.
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      78. Nordström A, O'Maille G, Qin C, Siuzdak G. Nonlinear data alignment for UPLC-MS and HPLC-MS based metabolomics: quantitative analysis of endogenous and exogenous metabolites in human serum. Anal Chem. 2006 May 15; 78(10):3289-95.
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      79. Lee JC, Wu CY, Apon JV, Siuzdak G, Wong CH. Reactivity-based one-pot synthesis of the tumor-associated antigen N3 minor octasaccharide for the development of a photocleavable DIOS-MS sugar array. Angew Chem Int Ed Engl. 2006 Apr 21; 45(17):2753-7.
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      80. Smith CA, Want EJ, O'Maille G, Abagyan R, Siuzdak G. XCMS: processing mass spectrometry data for metabolite profiling using nonlinear peak alignment, matching, and identification. Anal Chem. 2006 Feb 1; 78(3):779-87.
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      81. Want EJ, O'Maille G, Smith CA, Brandon TR, Uritboonthai W, Qin C, Trauger SA, Siuzdak G. Solvent-dependent metabolite distribution, clustering, and protein extraction for serum profiling with mass spectrometry. Anal Chem. 2006 Feb 1; 78(3):743-52.
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      82. Nordström A, Apon JV, Uritboonthai W, Go EP, Siuzdak G. Surfactant-enhanced desorption/ionization on silicon mass spectrometry. Anal Chem. 2006 Jan 1; 78(1):272-8.
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      83. Steenwyk RC, Hutzler JM, Sams J, Shen Z, Siuzdak G. Atmospheric pressure desorption/ionization on silicon ion trap mass spectrometry applied to the quantitation of midazolam in rat plasma and determination of midazolam 1'-hydroxylation kinetics in human liver microsomes. Rapid Commun Mass Spectrom. 2006; 20(24):3717-22.
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      84. Luo G, Chen Y, Siuzdak G, Vertes A. Surface modification and laser pulse length effects on internal energy transfer in DIOS. J Phys Chem B. 2005 Dec 29; 109(51):24450-6.
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      85. Smith CA, O'Maille G, Want EJ, Qin C, Trauger SA, Brandon TR, Custodio DE, Abagyan R, Siuzdak G. METLIN: a metabolite mass spectral database. Ther Drug Monit. 2005 Dec; 27(6):747-51.
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      86. Talkington MW, Siuzdak G, Williamson JR. An assembly landscape for the 30S ribosomal subunit. Nature. 2005 Dec 1; 438(7068):628-32.
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      87. Want EJ, Cravatt BF, Siuzdak G. The expanding role of mass spectrometry in metabolite profiling and characterization. Chembiochem. 2005 Nov; 6(11):1941-51.
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      88. Lacy ER, Wang Y, Post J, Nourse A, Webb W, Mapelli M, Musacchio A, Siuzdak G, Kriwacki RW. Molecular basis for the specificity of p27 toward cyclin-dependent kinases that regulate cell division. J Mol Biol. 2005 Jun 17; 349(4):764-73.
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      89. Bothner B, Taylor D, Jun B, Lee KK, Siuzdak G, Schultz CP, Schlutz CP, Johnson JE. Maturation of a tetravirus capsid alters the dynamic properties and creates a metastable complex. Virology. 2005 Mar 30; 334(1):17-27.
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      90. Go EP, Apon JV, Luo G, Saghatelian A, Daniels RH, Sahi V, Dubrow R, Cravatt BF, Vertes A, Siuzdak G. Desorption/ionization on silicon nanowires. Anal Chem. 2005 Mar 15; 77(6):1641-6.
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      91. Saghatelian A, Trauger SA, Want EJ, Hawkins EG, Siuzdak G, Cravatt BF. Assignment of endogenous substrates to enzymes by global metabolite profiling. Biochemistry. 2004 Nov 16; 43(45):14332-9.
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      92. Shen Z, Thomas JJ, Siuzdak G, Blackledge RD. A case study on forensic polymer analysis by DIOS-MS: the suspect who gave us the SLIP. J Forensic Sci. 2004 Sep; 49(5):1028-35.
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      93. Trauger SA, Wu E, Bark SJ, Nemerow GR, Siuzdak G. The identification of an adenovirus receptor by using affinity capture and mass spectrometry. Chembiochem. 2004 Aug 6; 5(8):1095-9.
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      94. Meng JC, Siuzdak G, Finn MG. Affinity mass spectrometry from a tailored porous silicon surface. Chem Commun (Camb). 2004 Sep 21; (18):2108-9.
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      95. Trauger SA, Go EP, Shen Z, Apon JV, Compton BJ, Bouvier ES, Finn MG, Siuzdak G. High sensitivity and analyte capture with desorption/ionization mass spectrometry on silylated porous silicon. Anal Chem. 2004 Aug 1; 76(15):4484-9.
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      96. Shen Z, Go EP, Gamez A, Apon JV, Fokin V, Greig M, Ventura M, Crowell JE, Blixt O, Paulson JC, Stevens RC, Finn MG, Siuzdak G. A mass spectrometry plate reader: monitoring enzyme activity and inhibition with a Desorption/Ionization on Silicon (DIOS) platform. Chembiochem. 2004 Jul 5; 5(7):921-7.
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      97. Wu E, Trauger SA, Pache L, Mullen TM, von Seggern DJ, Siuzdak G, Nemerow GR. Membrane cofactor protein is a receptor for adenoviruses associated with epidemic keratoconjunctivitis. J Virol. 2004 Apr; 78(8):3897-905.
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      98. Bothner B, Siuzdak G. Electrospray ionization of a whole virus: analyzing mass, structure, and viability. Chembiochem. 2004 Mar 5; 5(3):258-60.
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      99. Meng JC, Averbuj C, Lewis WG, Siuzdak G, Finn MG. Cleavable linkers for porous silicon-based mass spectrometry. Angew Chem Int Ed Engl. 2004 Feb 27; 43(10):1255-60.
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      100. Go EP, Shen Z, Harris K, Siuzdak G. Quantitative analysis with desorption/ionization on silicon mass spectrometry using electrospray deposition. Anal Chem. 2003 Oct 15; 75(20):5475-9.
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      101. Reisdorph N, Thomas JJ, Katpally U, Chase E, Harris K, Siuzdak G, Smith TJ. Human rhinovirus capsid dynamics is controlled by canyon flexibility. Virology. 2003 Sep 15; 314(1):34-44.
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      102. Go EP, Prenni JE, Wei J, Jones A, Hall SC, Witkowska HE, Shen Z, Siuzdak G. Desorption/ionization on silicon time-of-flight/time-of-flight mass spectrometry. Anal Chem. 2003 May 15; 75(10):2504-6.
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      103. Yao S, Meng JC, Siuzdak G, Finn MG. New catalysts for the asymmetric hydrosilylation of ketones discovered by mass spectrometry screening. J Org Chem. 2003 Apr 4; 68(7):2540-6.
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      104. Smith TJ, Schmidt T, Fang J, Wu J, Siuzdak G, Stanley CA. The structure of apo human glutamate dehydrogenase details subunit communication and allostery. J Mol Biol. 2002 May 3; 318(3):765-77.
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      105. Thomas JJ, Shen Z, Crowell JE, Finn MG, Siuzdak G. Desorption/ionization on silicon (DIOS): a diverse mass spectrometry platform for protein characterization. Proc Natl Acad Sci U S A. 2001 Apr 24; 98(9):4932-7.
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      106. Bark SJ, Muster N, Yates JR, Siuzdak G. High-temperature protein mass mapping using a thermophilic protease. J Am Chem Soc. 2001 Feb 28; 123(8):1774-5.
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      107. Broo K, Wei J, Marshall D, Brown F, Smith TJ, Johnson JE, Schneemann A, Siuzdak G. Viral capsid mobility: a dynamic conduit for inactivation. Proc Natl Acad Sci U S A. 2001 Feb 27; 98(5):2274-7.
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      108. Shen Z, Thomas JJ, Averbuj C, Broo KM, Engelhard M, Crowell JE, Finn MG, Siuzdak G. Porous silicon as a versatile platform for laser desorption/ionization mass spectrometry. Anal Chem. 2001 Feb 1; 73(3):612-9.
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      109. Bothner B, Chavez R, Wei J, Strupp C, Phung Q, Schneemann A, Siuzdak G. Monitoring enzyme catalysis with mass spectrometry. J Biol Chem. 2000 May 5; 275(18):13455-9.
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      110. Thomas JJ, Bakhtiar R, Siuzdak G. Mass spectrometry in viral proteomics. Acc Chem Res. 2000 Mar; 33(3):179-87.
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      111. Kriwacki RW, Siuzdak G. Probing protein-protein interactions with mass spectrometry. Methods Mol Biol. 2000; 146:223-38.
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      112. Yang C, Gu ZW, Yang M, Lin SN, Siuzdak G, Smith CV. Identification of modified tryptophan residues in apolipoprotein B-100 derived from copper ion-oxidized low-density lipoprotein. Biochemistry. 1999 Nov 30; 38(48):15903-8.
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      113. Chatman K, Hollenbeck T, Hagey L, Vallee M, Purdy R, Weiss F, Siuzdak G. Nanoelectrospray mass spectrometry and precursor ion monitoring for quantitative steroid analysis and attomole sensitivity. Anal Chem. 1999 Jul 1; 71(13):2358-63.
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      114. Hollenbeck TP, Siuzdak G, Blackledge RD. Electrospray and MALDI mass spectrometry in the identification of spermicides in criminal investigations. J Forensic Sci. 1999 Jul; 44(4):783-8.
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      115. Wei J, Buriak JM, Siuzdak G. Desorption-ionization mass spectrometry on porous silicon. Nature. 1999 May 20; 399(6733):243-6.
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      116. Bothner B, Schneemann A, Marshall D, Reddy V, Johnson JE, Siuzdak G. Crystallographically identical virus capsids display different properties in solution. Nat Struct Biol. 1999 Feb; 6(2):114-6.
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      117. Takayama S, Chung SJ, Igarashi Y, Ichikawa Y, Sepp A, Lechler RI, Wu J, Hayashi T, Siuzdak G, Wong CH. Selective inhibition of beta-1,4- and alpha-1,3-galactosyltransferases: donor sugar-nucleotide based approach. Bioorg Med Chem. 1999 Feb; 7(2):401-9.
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      118. Marmey P, Bothner B, Jacquot E, de Kochko A, Ong CA, Yot P, Siuzdak G, Beachy RN, Fauquet CM. Rice tungro bacilliform virus open reading frame 3 encodes a single 37-kDa coat protein. Virology. 1999 Jan 20; 253(2):319-26.
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      119. Tsui V, Garcia C, Cavagnero S, Siuzdak G, Dyson HJ, Wright PE. Quench-flow experiments combined with mass spectrometry show apomyoglobin folds through and obligatory intermediate. Protein Sci. 1999 Jan; 8(1):45-9.
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      120. Owens DR, Bothner B, Phung Q, Harris K, Siuzdak G. Aspects of oligonucleotide and peptide sequencing with MALDI and electrospray mass spectrometry. Bioorg Med Chem. 1998 Sep; 6(9):1547-54.
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      121. Lewis JK, Bendahmane M, Smith TJ, Beachy RN, Siuzdak G. Identification of viral mutants by mass spectrometry. Proc Natl Acad Sci U S A. 1998 Jul 21; 95(15):8596-601.
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      122. Lewis JK, Bothner B, Smith TJ, Siuzdak G. Antiviral agent blocks breathing of the common cold virus. Proc Natl Acad Sci U S A. 1998 Jun 9; 95(12):6774-8.
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      123. Siuzdak G. Probing viruses with mass spectrometry. J Mass Spectrom. 1998 Mar; 33(3):203-11.
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      124. Bothner B, Dong XF, Bibbs L, Johnson JE, Siuzdak G. Evidence of viral capsid dynamics using limited proteolysis and mass spectrometry. J Biol Chem. 1998 Jan 9; 273(2):673-6.
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      125. Siuzdak G, Lewis JK. Applications of mass spectrometry in combinatorial chemistry. Biotechnol Bioeng. 1998; 61(2):127-34.
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      126. Wu J, Chatman K, Harris K, Siuzdak G. An automated MALDI mass spectrometry approach for optimizing cyclosporin extraction and quantitation. Anal Chem. 1997 Sep 15; 69(18):3767-71.
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      127. Wu J, Takayama S, Wong CH, Siuzdak G. Quantitative electrospray mass spectrometry for the rapid assay of enzyme inhibitors. Chem Biol. 1997 Sep; 4(9):653-7.
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      128. Kriwacki RW, Wu J, Tennant L, Wright PE, Siuzdak G. Probing protein structure using biochemical and biophysical methods. Proteolysis, matrix-assisted laser desorption/ionization mass spectrometry, high-performance liquid chromatography and size-exclusion chromatography of p21Waf1/Cip1/Sdi1. J Chromatogr A. 1997 Aug 8; 777(1):23-30.
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      129. Fitzgerald MC, Siuzdak G. Biochemical mass spectrometry: worth the weight? Chem Biol. 1996 Sep; 3(9):707-15.
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      130. Siuzdak G, Bothner B, Yeager M, Brugidou C, Fauquet CM, Hoey K, Chang CM. Mass spectrometry and viral analysis. Chem Biol. 1996 Jan; 3(1):45-8.
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      131. Cravatt BF, Prospero-Garcia O, Siuzdak G, Gilula NB, Henriksen SJ, Boger DL, Lerner RA. Chemical characterization of a family of brain lipids that induce sleep. Science. 1995 Jun 9; 268(5216):1506-9.
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      132. Krebs JF, Siuzdak G, Dyson HJ, Stewart JD, Benkovic SJ. Detection of a catalytic antibody species acylated at the active site by electrospray mass spectrometry. Biochemistry. 1995 Jan 24; 34(3):720-3.
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      133. Siuzdak G. The emergence of mass spectrometry in biochemical research. Proc Natl Acad Sci U S A. 1994 Nov 22; 91(24):11290-7.
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      134. Lerner RA, Siuzdak G, Prospero-Garcia O, Henriksen SJ, Boger DL, Cravatt BF. Cerebrodiene: a brain lipid isolated from sleep-deprived cats. Proc Natl Acad Sci U S A. 1994 Sep 27; 91(20):9505-8.
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      135. Stewart JD, Krebs JF, Siuzdak G, Berdis AJ, Smithrud DB, Benkovic SJ. Dissection of an antibody-catalyzed reaction. Proc Natl Acad Sci U S A. 1994 Aug 2; 91(16):7404-9.
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      136. Rideout D, Bustamante A, Siuzdak G. Cationic drug analysis using matrix-assisted laser desorption/ionization mass spectrometry: application to influx kinetics, multidrug resistance, and intracellular chemical change. Proc Natl Acad Sci U S A. 1993 Nov 1; 90(21):10226-9.
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