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    Chang, Christopher

    TitleChemist Faculty
    SchoolLawrence Berkeley National Lab
    DepartmentChemical Sciences
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/642-4704
    vCardDownload vCard

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      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can login to make corrections and additions, or contact us for help.
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      1. Diercks CS, Lin S, Kornienko N, Kapustin EA, Nichols EM, Zhu C, Zhao Y, Chang C, Yaghi OM. Reticular Electronic Tuning of Porphyrin Active Sites in Covalent Organic Frameworks for Electrocatalytic Carbon Dioxide Reduction. J Am Chem Soc. 2018 Jan 16. PMID: 29284263.
        View in: PubMed
      2. Aron AT, Reeves AG, Chang C. Activity-based sensing fluorescent probes for iron in biological systems. Curr Opin Chem Biol. 2018 Jan 04; 43:113-118. PMID: 29306820.
        View in: PubMed
      3. Jia S, Ramos-Torres KM, Kolemen S, Ackerman CM, Chang C. Tuning the Color Palette of Fluorescent Copper Sensors through Systematic Heteroatom Substitution at Rhodol Cores. ACS Chem Biol. 2017 Nov 07. PMID: 29112372.
        View in: PubMed
      4. Gong M, Cao Z, Liu W, Nichols EM, Smith PT, Derrick JS, Liu YS, Liu J, Wen X, Chang C. Supramolecular Porphyrin Cages Assembled at Molecular-Materials Interfaces for Electrocatalytic CO Reduction. ACS Cent Sci. 2017 Sep 27; 3(9):1032-1040. PMID: 28979945.
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      5. Bruemmer KJ, Brewer TF, Chang C. Fluorescent probes for imaging formaldehyde in biological systems. Curr Opin Chem Biol. 2017 Aug; 39:17-23. PMID: 28527906.
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      6. Brewer TF, Burgos-Barragan G, Wit N, Patel KJ, Chang C. A 2-aza-Cope reactivity-based platform for ratiometric fluorescence imaging of formaldehyde in living cells. Chem Sci. 2017 May 01; 8(5):4073-4081. PMID: 28580121.
        View in: PubMed
      7. Chang C. Bioinorganic Life and Neural Activity: Toward a Chemistry of Consciousness? Acc Chem Res. 2017 Mar 21; 50(3):535-538. PMID: 28945425.
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      8. Lin S, Yang X, Jia S, Weeks AM, Hornsby M, Lee PS, Nichiporuk RV, Iavarone AT, Wells JA, Toste FD, Chang C. Redox-based reagents for chemoselective methionine bioconjugation. Science. 2017 02 10; 355(6325):597-602. PMID: 28183972.
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      9. Ackerman CM, Lee S, Chang C. Analytical Methods for Imaging Metals in Biology: From Transition Metal Metabolism to Transition Metal Signaling. Anal Chem. 2017 01 03; 89(1):22-41. PMID: 27976855.
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      10. Heffern MC, Park HM, Au-Yeung HY, Van de Bittner GC, Ackerman CM, Stahl A, Chang C. In vivo bioluminescence imaging reveals copper deficiency in a murine model of nonalcoholic fatty liver disease. Proc Natl Acad Sci U S A. 2016 Dec 13; 113(50):14219-14224. PMID: 27911810.
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      11. Aron AT, Loehr MO, Bogena J, Chang C. An Endoperoxide Reactivity-Based FRET Probe for Ratiometric Fluorescence Imaging of Labile Iron Pools in Living Cells. J Am Chem Soc. 2016 Nov 02; 138(43):14338-14346. PMID: 27768321.
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      12. Huet O, Pickering RJ, Tikellis C, Latouche C, Long F, Kingwell B, Dickinson B, Chang C, Masters S, Mackay F, Cooper ME, de Haan JB. Protective Effect of Inflammasome Activation by Hydrogen Peroxide in a Mouse Model of Septic Shock. Crit Care Med. 2016 Oct 3. PMID: 27749344.
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      13. Axelson JC, Gonzalez MI, Meihaus KR, Chang C, Long JR. Synthesis and Characterization of a Tetrapodal NO4(4-) Ligand and Its Transition Metal Complexes. Inorg Chem. 2016 Aug 01; 55(15):7527-34. PMID: 27404805.
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      14. Spangler B, Morgan CW, Fontaine SD, Vander Wal MN, Chang C, Wells JA, Renslo AR. A reactivity-based probe of the intracellular labile ferrous iron pool. Nat Chem Biol. 2016 Sep; 12(9):680-5. PMID: 27376690; PMCID: PMC4990480 [Available on 01/04/17].
      15. Cao Z, Kim D, Hong D, Yu Y, Xu J, Lin S, Wen X, Nichols EM, Jeong K, Reimer JA, Yang P, Chang C. A Molecular Surface Functionalization Approach to Tuning Nanoparticle Electrocatalysts for Carbon Dioxide Reduction. J Am Chem Soc. 2016 Jul 06; 138(26):8120-5. PMID: 27322487.
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      16. Chang C. A Triple Crown of Sustainable Synthesis. ACS Cent Sci. 2016 May 25; 2(5):266-7. PMID: 27280158; PMCID: PMC4882736.
      17. Bertozzi CR, Chang C, Davis BG, Olvera de la Cruz M, Tirrell DA, Zhao D. Grand Challenges in Chemistry for 2016 and Beyond. ACS Cent Sci. 2016 Jan 27; 2(1):1-3. PMID: 27163017; PMCID: PMC4827666.
      18. Chang C. The Joy of Synthesis. ACS Cent Sci. 2015 Nov 25; 1(8):409. PMID: 27162999; PMCID: PMC4827497.
      19. Kornienko N, Zhao Y, Kley CS, Zhu C, Kim D, Lin S, Chang C, Yaghi OM, Yang P. Metal-organic frameworks for electrocatalytic reduction of carbon dioxide. J Am Chem Soc. 2015 Nov 11; 137(44):14129-35. PMID: 26509213.
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      20. Brewer TF, Chang C. An Aza-Cope Reactivity-Based Fluorescent Probe for Imaging Formaldehyde in Living Cells. J Am Chem Soc. 2015 Sep 02; 137(34):10886-9. PMID: 26306005.
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      21. Nichols EM, Gallagher JJ, Liu C, Su Y, Resasco J, Yu Y, Sun Y, Yang P, Chang MC, Chang C. Hybrid bioinorganic approach to solar-to-chemical conversion. Proc Natl Acad Sci U S A. 2015 Sep 15; 112(37):11461-6. PMID: 26305947; PMCID: PMC4577177.
      22. Lin S, Diercks CS, Zhang YB, Kornienko N, Nichols EM, Zhao Y, Paris AR, Kim D, Yang P, Yaghi OM, Chang C. Covalent organic frameworks comprising cobalt porphyrins for catalytic CO2 reduction in water. Science. 2015 Sep 11; 349(6253):1208-13. PMID: 26292706.
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      23. Aron AT, Ramos-Torres KM, Cotruvo JA, Chang C. Recognition- and reactivity-based fluorescent probes for studying transition metal signaling in living systems. Acc Chem Res. 2015 Aug 18; 48(8):2434-42. PMID: 26215055; PMCID: PMC4542203.
      24. Lin VS, Chen W, Xian M, Chang C. Chemical probes for molecular imaging and detection of hydrogen sulfide and reactive sulfur species in biological systems. Chem Soc Rev. 2015 Jul 21; 44(14):4596-4618. PMID: 25474627; PMCID: PMC4456340.
      25. Chang C, Gunnlaugsson T, James TD. Imaging agents. Chem Soc Rev. 2015 Jul 21; 44(14):4484-6. PMID: 26107987.
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      26. Zee DZ, Chantarojsiri T, Long JR, Chang C. Metal-polypyridyl catalysts for electro- and photochemical reduction of water to hydrogen. Acc Chem Res. 2015 Jul 21; 48(7):2027-36. PMID: 26101803.
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      27. Chang C, Gunnlaugsson T, James TD. Sensor targets. Chem Soc Rev. 2015 Jul 07; 44(13):4176-8. PMID: 26065648.
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      28. Jurss JW, Khnayzer RS, Panetier JA, El Roz KA, Nichols EM, Head-Gordon M, Long JR, Castellano FN, Chang C. Bioinspired design of redox-active ligands for multielectron catalysis: effects of positioning pyrazine reservoirs on cobalt for electro- and photocatalytic generation of hydrogen from water. Chem Sci. 2015 Aug 01; 6(8):4954-4972. PMID: 29142725.
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      29. Chantarojsiri T, Sun Y, Long JR, Chang C. Water-Soluble Iron(IV)-Oxo Complexes Supported by Pentapyridine Ligands: Axial Ligand Effects on Hydrogen Atom and Oxygen Atom Transfer Reactivity. Inorg Chem. 2015 Jun 15; 54(12):5879-87. PMID: 26039655.
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      30. Liu C, Gallagher JJ, Sakimoto KK, Nichols EM, Chang C, Chang MC, Yang P. Nanowire-bacteria hybrids for unassisted solar carbon dioxide fixation to value-added chemicals. Nano Lett. 2015 May 13; 15(5):3634-9. PMID: 25848808.
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      31. Cotruvo JA, Aron AT, Ramos-Torres KM, Chang C. Synthetic fluorescent probes for studying copper in biological systems. Chem Soc Rev. 2015 Jul 07; 44(13):4400-14. PMID: 25692243; PMCID: PMC4478099.
      32. Chang C, Cravatt BF, Johnson DS, Lim MH. Molecular medicine and neurodegenerative diseases. Chem Soc Rev. 2014 Oct 07; 43(19):6668-71. PMID: 25105517.
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      33. King AE, Nippe M, Atanasov M, Chantarojsiri T, Wray CA, Bill E, Neese F, Long JR, Chang C. A well-defined terminal vanadium(III) oxo complex. Inorg Chem. 2014 Nov 03; 53(21):11388-95. PMID: 25097094.
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      34. Chan J, Chang C. Making light of stress. Nat Biotechnol. 2014 Apr; 32(4):337-8. PMID: 24714482.
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      35. Chang C, Raymond KN. Preface for the forum on imaging and sensing: probing and utilizing the elements of life for studying and improving health and society. Inorg Chem. 2014 Feb 17; 53(4):1791-3. PMID: 24506438.
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      36. Sun Y, Liu C, Grauer DC, Yano J, Long JR, Yang P, Chang C. Electrodeposited cobalt-sulfide catalyst for electrochemical and photoelectrochemical hydrogen generation from water. J Am Chem Soc. 2013 Nov 27; 135(47):17699-702. PMID: 24219808.
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      37. Au-Yeung HY, Chan J, Chantarojsiri T, Chang C. Molecular imaging of labile iron(II) pools in living cells with a turn-on fluorescent probe. J Am Chem Soc. 2013 Oct 09; 135(40):15165-73. PMID: 24063668; PMCID: PMC3838104.
      38. Thoi VS, Kornienko N, Margarit CG, Yang P, Chang C. Visible-light photoredox catalysis: selective reduction of carbon dioxide to carbon monoxide by a nickel N-heterocyclic carbene-isoquinoline complex. J Am Chem Soc. 2013 Sep 25; 135(38):14413-24. PMID: 24033186.
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      39. Dickinson BC, Lin VS, Chang C. Preparation and use of MitoPY1 for imaging hydrogen peroxide in mitochondria of live cells. Nat Protoc. 2013 Jun; 8(6):1249-59. PMID: 23722262; PMCID: PMC4096497.
      40. Lin VS, Lippert AR, Chang C. Cell-trappable fluorescent probes for endogenous hydrogen sulfide signaling and imaging H2O2-dependent H2S production. Proc Natl Acad Sci U S A. 2013 Apr 30; 110(18):7131-5. PMID: 23589874; PMCID: PMC3645565.
      41. Van de Bittner GC, Bertozzi CR, Chang C. Strategy for dual-analyte luciferin imaging: in vivo bioluminescence detection of hydrogen peroxide and caspase activity in a murine model of acute inflammation. J Am Chem Soc. 2013 Feb 06; 135(5):1783-95. PMID: 23347279; PMCID: PMC3583381.
      42. Chan J, Dodani SC, Chang C. Reaction-based small-molecule fluorescent probes for chemoselective bioimaging. Nat Chem. 2012 Dec; 4(12):973-84. PMID: 23174976; PMCID: PMC4096518.
      43. Thoi VS, Sun Y, Long JR, Chang C. Complexes of earth-abundant metals for catalytic electrochemical hydrogen generation under aqueous conditions. Chem Soc Rev. 2013 Mar 21; 42(6):2388-400. PMID: 23034627.
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      44. Michel BW, Lippert AR, Chang C. A reaction-based fluorescent probe for selective imaging of carbon monoxide in living cells using a palladium-mediated carbonylation. J Am Chem Soc. 2012 Sep 26; 134(38):15668-71. PMID: 22970765.
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      45. Harman WH, Lichterman MF, Piro NA, Chang C. Well-defined vanadium organoazide complexes and their conversion to terminal vanadium imides: structural snapshots and evidence for a nitrene capture mechanism. Inorg Chem. 2012 Sep 17; 51(18):10037-42. PMID: 22920922.
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      46. Lin VS, Chang C. Fluorescent probes for sensing and imaging biological hydrogen sulfide. Curr Opin Chem Biol. 2012 Dec; 16(5-6):595-601. PMID: 22921406; PMCID: PMC3509267.
      47. Que EL, New EJ, Chang C. A cell-permeable gadolinium contrast agent for magnetic resonance imaging of copper in a Menkes disease model. Chem Sci. 2012 Jun 01; 3(6):1829-1834. PMID: 25431649.
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      48. Au-Yeung HY, New EJ, Chang C. A selective reaction-based fluorescent probe for detecting cobalt in living cells. Chem Commun (Camb). 2012 May 28; 48(43):5268-70. PMID: 22531796.
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      49. Sundstrom EJ, Yang X, Thoi VS, Karunadasa HI, Chang C, Long JR, Head-Gordon M. Computational and experimental study of the mechanism of hydrogen generation from water by a molecular molybdenum-oxo electrocatalyst. J Am Chem Soc. 2012 Mar 21; 134(11):5233-42. PMID: 22356562.
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      50. Karunadasa HI, Montalvo E, Sun Y, Majda M, Long JR, Chang C. A molecular MoS2 edge site mimic for catalytic hydrogen generation. Science. 2012 Feb 10; 335(6069):698-702. PMID: 22323816.
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      51. Hirayama T, Van de Bittner GC, Gray LW, Lutsenko S, Chang C. Near-infrared fluorescent sensor for in vivo copper imaging in a murine Wilson disease model. Proc Natl Acad Sci U S A. 2012 Feb 14; 109(7):2228-33. PMID: 22308360; PMCID: PMC3289337.
      52. Zadrozny JM, Liu J, Piro NA, Chang C, Hill S, Long JR. Slow magnetic relaxation in a pseudotetrahedral cobalt(II) complex with easy-plane anisotropy. Chem Commun (Camb). 2012 Apr 25; 48(33):3927-9. PMID: 22222273.
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      53. Bigi JP, Harman WH, Lassalle-Kaiser B, Robles DM, Stich TA, Yano J, Britt RD, Chang C. A high-spin iron(IV)-oxo complex supported by a trigonal nonheme pyrrolide platform. J Am Chem Soc. 2012 Jan 25; 134(3):1536-42. PMID: 22214221.
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      54. Dickinson BC, Tang Y, Chang Z, Chang C. A nuclear-localized fluorescent hydrogen peroxide probe for monitoring sirtuin-mediated oxidative stress responses in vivo. Chem Biol. 2011 Aug 26; 18(8):943-8. PMID: 21867909; PMCID: PMC3173257.
      55. Lippert AR, Van de Bittner GC, Chang C. Boronate oxidation as a bioorthogonal reaction approach for studying the chemistry of hydrogen peroxide in living systems. Acc Chem Res. 2011 Sep 20; 44(9):793-804. PMID: 21834525; PMCID: PMC3178007.
      56. Lippert AR, New EJ, Chang C. Reaction-based fluorescent probes for selective imaging of hydrogen sulfide in living cells. J Am Chem Soc. 2011 Jul 06; 133(26):10078-80. PMID: 21671682.
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      57. Sun Y, Bigi JP, Piro NA, Tang ML, Long JR, Chang C. Molecular cobalt pentapyridine catalysts for generating hydrogen from water. J Am Chem Soc. 2011 Jun 22; 133(24):9212-5. PMID: 21612276.
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      58. Dodani SC, Leary SC, Cobine PA, Winge DR, Chang C. A targetable fluorescent sensor reveals that copper-deficient SCO1 and SCO2 patient cells prioritize mitochondrial copper homeostasis. J Am Chem Soc. 2011 Jun 08; 133(22):8606-16. PMID: 21563821; PMCID: PMC3106114.
      59. Thoi VS, Chang C. Nickel N-heterocyclic carbene-pyridine complexes that exhibit selectivity for electrocatalytic reduction of carbon dioxide over water. Chem Commun (Camb). 2011 Jun 21; 47(23):6578-80. PMID: 21556400.
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      60. Dodani SC, Domaille DW, Nam CI, Miller EW, Finney LA, Vogt S, Chang C. Calcium-dependent copper redistributions in neuronal cells revealed by a fluorescent copper sensor and X-ray fluorescence microscopy. Proc Natl Acad Sci U S A. 2011 Apr 12; 108(15):5980-5. PMID: 21444780; PMCID: PMC3076884.
      61. Lippert AR, Keshari KR, Kurhanewicz J, Chang C. A hydrogen peroxide-responsive hyperpolarized 13C MRI contrast agent. J Am Chem Soc. 2011 Mar 23; 133(11):3776-9. PMID: 21366297; PMCID: PMC3060273.
      62. Piro NA, Lichterman MF, Harman WH, Chang C. A structurally characterized nitrous oxide complex of vanadium. J Am Chem Soc. 2011 Feb 23; 133(7):2108-11. PMID: 21287986.
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      63. Harman WH, Harris TD, Freedman DE, Fong H, Chang A, Rinehart JD, Ozarowski A, Sougrati MT, Grandjean F, Long GJ, Long JR, Chang C. Slow magnetic relaxation in a family of trigonal pyramidal iron(II) pyrrolide complexes. J Am Chem Soc. 2010 Dec 29; 132(51):18115-26. PMID: 21141856.
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      64. Van de Bittner GC, Dubikovskaya EA, Bertozzi CR, Chang C. In vivo imaging of hydrogen peroxide production in a murine tumor model with a chemoselective bioluminescent reporter. Proc Natl Acad Sci U S A. 2010 Dec 14; 107(50):21316-21. PMID: 21115844; PMCID: PMC3003011.
      65. Miller EW, Taulet N, Onak CS, New EJ, Lanselle JK, Smelick GS, Chang C. Light-activated regulation of cofilin dynamics using a photocaged hydrogen peroxide generator. J Am Chem Soc. 2010 Dec 08; 132(48):17071-3. PMID: 21077675.
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      66. Lippert AR, Gschneidtner T, Chang C. Lanthanide-based luminescent probes for selective time-gated detection of hydrogen peroxide in water and in living cells. Chem Commun (Camb). 2010 Oct 28; 46(40):7510-2. PMID: 20838673.
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      67. Miller EW, Dickinson BC, Chang C. Aquaporin-3 mediates hydrogen peroxide uptake to regulate downstream intracellular signaling. Proc Natl Acad Sci U S A. 2010 Sep 07; 107(36):15681-6. PMID: 20724658; PMCID: PMC2936599.
      68. Karunadasa HI, Chang C, Long JR. A molecular molybdenum-oxo catalyst for generating hydrogen from water. Nature. 2010 Apr 29; 464(7293):1329-33. PMID: 20428167.
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      69. Dickinson BC, Huynh C, Chang C. A palette of fluorescent probes with varying emission colors for imaging hydrogen peroxide signaling in living cells. J Am Chem Soc. 2010 Apr 28; 132(16):5906-15. PMID: 20361787; PMCID: PMC2862989.
      70. Srikun D, Albers AE, Nam CI, Iavarone AT, Chang C. Organelle-targetable fluorescent probes for imaging hydrogen peroxide in living cells via SNAP-Tag protein labeling. J Am Chem Soc. 2010 Mar 31; 132(12):4455-65. PMID: 20201528; PMCID: PMC2850560.
      71. Domaille DW, Zeng L, Chang C. Visualizing ascorbate-triggered release of labile copper within living cells using a ratiometric fluorescent sensor. J Am Chem Soc. 2010 Feb 03; 132(4):1194-5. PMID: 20052977; PMCID: PMC2819030.
      72. Freedman DE, Harman WH, Harris TD, Long GJ, Chang C, Long JR. Slow magnetic relaxation in a high-spin iron(II) complex. J Am Chem Soc. 2010 Feb 03; 132(4):1224-5. PMID: 20055389.
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      73. Dodani SC, He Q, Chang C. A turn-on fluorescent sensor for detecting nickel in living cells. J Am Chem Soc. 2009 Dec 23; 131(50):18020-1. PMID: 19950946; PMCID: PMC2810492.
      74. Bigi JP, Hanna TE, Harman WH, Chang A, Chang C. Electrocatalytic reduction of protons to hydrogen by a water-compatible cobalt polypyridyl platform. Chem Commun (Camb). 2010 Feb 14; 46(6):958-60. PMID: 20107663.
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      75. Que EL, Gianolio E, Baker SL, Aime S, Chang C. A copper-activated magnetic resonance imaging contrast agent with improved turn-on relaxivity response and anion compatibility. Dalton Trans. 2010 Jan 14; (2):469-76. PMID: 20023983.
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      76. Dickinson BC, Srikun D, Chang C. Mitochondrial-targeted fluorescent probes for reactive oxygen species. Curr Opin Chem Biol. 2010 Feb; 14(1):50-6. PMID: 19910238; PMCID: PMC2830890.
      77. Soo HS, Komor AC, Iavarone AT, Chang C. A hydrogen-bond facilitated cycle for oxygen reduction by an acid- and base-compatible iron platform. Inorg Chem. 2009 Nov 02; 48(21):10024-35. PMID: 19780564.
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      78. Que EL, Chang C. Responsive magnetic resonance imaging contrast agents as chemical sensors for metals in biology and medicine. Chem Soc Rev. 2010 Jan; 39(1):51-60. PMID: 20023836.
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      79. Que EL, Gianolio E, Baker SL, Wong AP, Aime S, Chang C. Copper-responsive magnetic resonance imaging contrast agents. J Am Chem Soc. 2009 Jun 24; 131(24):8527-36. PMID: 19489557.
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      80. Albers AE, Dickinson BC, Miller EW, Chang C. A red-emitting naphthofluorescein-based fluorescent probe for selective detection of hydrogen peroxide in living cells. Bioorg Med Chem Lett. 2008 Nov 15; 18(22):5948-50. PMID: 18762422; PMCID: PMC2590631.
      81. Dickinson BC, Chang C. A targetable fluorescent probe for imaging hydrogen peroxide in the mitochondria of living cells. J Am Chem Soc. 2008 Jul 30; 130(30):9638-9. PMID: 18605728; PMCID: PMC2810491.
      82. Que EL, Domaille DW, Chang C. Metals in neurobiology: probing their chemistry and biology with molecular imaging. Chem Rev. 2008 May; 108(5):1517-49. PMID: 18426241.
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      83. Srikun D, Miller EW, Domaille DW, Chang C. An ICT-based approach to ratiometric fluorescence imaging of hydrogen peroxide produced in living cells. J Am Chem Soc. 2008 Apr 09; 130(14):4596-7. PMID: 18336027.
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      84. Domaille DW, Que EL, Chang C. Synthetic fluorescent sensors for studying the cell biology of metals. Nat Chem Biol. 2008 Mar; 4(3):168-75. PMID: 18277978.
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      85. Miller EW, He Q, Chang C. Preparation and use of Leadfluor-1, a synthetic fluorophore for live-cell lead imaging. Nat Protoc. 2008; 3(5):777-83. PMID: 18451786.
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      86. Harman WH, Chang C. N2O activation and oxidation reactivity from a non-heme iron pyrrole platform. J Am Chem Soc. 2007 Dec 12; 129(49):15128-9. PMID: 18004860.
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      87. Miller EW, Chang C. Fluorescent probes for nitric oxide and hydrogen peroxide in cell signaling. Curr Opin Chem Biol. 2007 Dec; 11(6):620-5. PMID: 17967434; PMCID: PMC2693042.
      88. Albers AE, Rawls KA, Chang C. Activity-based fluorescent reporters for monoamine oxidases in living cells. Chem Commun (Camb). 2007 Nov 28; (44):4647-9. PMID: 17989820.
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      89. Miller EW, Tulyathan O, Tulyanthan O, Isacoff EY, Chang C. Molecular imaging of hydrogen peroxide produced for cell signaling. Nat Chem Biol. 2007 May; 3(5):263-7. PMID: 17401379.
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      90. Miller EW, Bian SX, Chang C. A fluorescent sensor for imaging reversible redox cycles in living cells. J Am Chem Soc. 2007 Mar 28; 129(12):3458-9. PMID: 17335279; PMCID: PMC2532511.
      91. Yoon S, Miller EW, He Q, Do PH, Chang C. A bright and specific fluorescent sensor for mercury in water, cells, and tissue. Angew Chem Int Ed Engl. 2007; 46(35):6658-61. PMID: 17665405.
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      92. Que EL, Chang C. A smart magnetic resonance contrast agent for selective copper sensing. J Am Chem Soc. 2006 Dec 20; 128(50):15942-3. PMID: 17165700.
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      93. Albers AE, Okreglak VS, Chang C. A FRET-based approach to ratiometric fluorescence detection of hydrogen peroxide. J Am Chem Soc. 2006 Aug 02; 128(30):9640-1. PMID: 16866512.
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      94. He Q, Miller EW, Wong AP, Chang C. A selective fluorescent sensor for detecting lead in living cells. J Am Chem Soc. 2006 Jul 26; 128(29):9316-7. PMID: 16848451.
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      95. Zeng L, Miller EW, Pralle A, Isacoff EY, Chang C. A selective turn-on fluorescent sensor for imaging copper in living cells. J Am Chem Soc. 2006 Jan 11; 128(1):10-1. PMID: 16390096; PMCID: PMC1414792.
      96. Miller EW, Zeng L, Domaille DW, Chang C. Preparation and use of Coppersensor-1, a synthetic fluorophore for live-cell copper imaging. Nat Protoc. 2006; 1(2):824-7. PMID: 17406313.
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      97. Miller EW, Albers AE, Pralle A, Isacoff EY, Chang C. Boronate-based fluorescent probes for imaging cellular hydrogen peroxide. J Am Chem Soc. 2005 Nov 30; 127(47):16652-9. PMID: 16305254; PMCID: PMC1447675.
      98. Yoon S, Albers AE, Wong AP, Chang C. Screening mercury levels in fish with a selective fluorescent chemosensor. J Am Chem Soc. 2005 Nov 23; 127(46):16030-1. PMID: 16287282.
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      99. Chang MC, Pralle A, Isacoff EY, Chang C. A selective, cell-permeable optical probe for hydrogen peroxide in living cells. J Am Chem Soc. 2004 Dec 01; 126(47):15392-3. PMID: 15563161; PMCID: PMC1434465.
      100. Chang C, Nolan EM, Jaworski J, Okamoto K, Hayashi Y, Sheng M, Lippard SJ. ZP8, a neuronal zinc sensor with improved dynamic range; imaging zinc in hippocampal slices with two-photon microscopy. Inorg Chem. 2004 Oct 18; 43(21):6774-9. PMID: 15476377.
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      101. Chang C, Loh ZH, Shi C, Anson FC, Nocera DG. Targeted proton delivery in the catalyzed reduction of oxygen to water by bimetallic pacman porphyrins. J Am Chem Soc. 2004 Aug 18; 126(32):10013-20. PMID: 15303875.
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      102. Chang C, Jaworski J, Nolan EM, Sheng M, Lippard SJ. A tautomeric zinc sensor for ratiometric fluorescence imaging: application to nitric oxide-induced release of intracellular zinc. Proc Natl Acad Sci U S A. 2004 Feb 03; 101(5):1129-34. PMID: 14734801; PMCID: PMC337018.
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