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    22833 Publications
    3073 Total Profiles
    24 Edited Profiles

    Wyrobek, Andrew

    TitleGeneticist Senior Sci/Engr
    SchoolLawrence Berkeley National Lab
    DepartmentLife Sciences
    Address1 Cyclotron Road
    Berkeley CA 94720
    Phone510/486-7375

       Bibliographic 
       Publications
      Publications listed below are automatically derived from MEDLINE/PubMed and other sources, which might result in incorrect or missing publications. Researchers can sign in to make corrections and additions, or contact us for help.
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      1. Marchetti F, Bishop J, Gingerich J, Wyrobek AJ. Meiotic interstrand DNA damage escapes paternal repair and causes chromosomal aberrations in the zygote by maternal misrepair. Sci Rep. 2015; 5:7689.
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      2. Snijders AM, Langley S, Mao JH, Bhatnagar S, Bjornstad KA, Rosen CJ, Lo A, Huang Y, Blakely EA, Karpen GH, Bissell MJ, Wyrobek AJ. An interferon signature identified by RNA-sequencing of mammary tissues varies across the estrous cycle and is predictive of metastasis-free survival. Oncotarget. 2014 Jun 30; 5(12):4011-25.
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      3. Kim D, Marchetti F, Chen Z, Zaric S, Wilson RJ, Hall DA, Gaster RS, Lee JR, Wang J, Osterfeld SJ, Yu H, White RM, Blakely WF, Peterson LE, Bhatnagar S, Mannion B, Tseng S, Roth K, Coleman M, Snijders AM, Wyrobek AJ, Wang SX. Nanosensor dosimetry of mouse blood proteins after exposure to ionizing radiation. Sci Rep. 2013; 3:2234.
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      4. Budworth H, Snijders AM, Marchetti F, Mannion B, Bhatnagar S, Kwoh E, Tan Y, Wang SX, Blakely WF, Coleman M, Peterson L, Wyrobek AJ. DNA repair and cell cycle biomarkers of radiation exposure and inflammation stress in human blood. PLoS One. 2012; 7(11):e48619.
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      5. Snijders AM, Marchetti F, Bhatnagar S, Duru N, Han J, Hu Z, Mao JH, Gray JW, Wyrobek AJ. Genetic differences in transcript responses to low-dose ionizing radiation identify tissue functions associated with breast cancer susceptibility. PLoS One. 2012; 7(10):e45394.
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      6. Schmid TE, Grant PG, Marchetti F, Weldon RH, Eskenazi B, Wyrobek AJ. Elemental composition of human semen is associated with motility and genomic sperm defects among older men. Hum Reprod. 2013 Jan; 28(1):274-82.
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      7. Schmid TE, Eskenazi B, Marchetti F, Young S, Weldon RH, Baumgartner A, Anderson D, Wyrobek AJ. Micronutrients intake is associated with improved sperm DNA quality in older men. Fertil Steril. 2012 Nov; 98(5):1130-7.e1.
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      8. Marchetti F, Eskenazi B, Weldon RH, Li G, Zhang L, Rappaport SM, Schmid TE, Xing C, Kurtovich E, Wyrobek AJ. Occupational exposure to benzene and chromosomal structural aberrations in the sperm of Chinese men. Environ Health Perspect. 2012 Feb; 120(2):229-34.
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      9. Wyrobek AJ, Manohar CF, Krishnan VV, Nelson DO, Furtado MR, Bhattacharya MS, Marchetti F, Coleman MA. Low dose radiation response curves, networks and pathways in human lymphoblastoid cells exposed from 1 to 10cGy of acute gamma radiation. Mutat Res. 2011 Jun 17; 722(2):119-30.
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      10. Lapuk A, Marr H, Jakkula L, Pedro H, Bhattacharya S, Purdom E, Hu Z, Simpson K, Pachter L, Durinck S, Wang N, Parvin B, Fontenay G, Speed T, Garbe J, Stampfer M, Bayandorian H, Dorton S, Clark TA, Schweitzer A, Wyrobek A, Feiler H, Spellman P, Conboy J, Gray JW. Exon-level microarray analyses identify alternative splicing programs in breast cancer. Mol Cancer Res. 2010 Jul; 8(7):961-74.
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      11. Xing C, Marchetti F, Li G, Weldon RH, Kurtovich E, Young S, Schmid TE, Zhang L, Rappaport S, Waidyanatha S, Wyrobek AJ, Eskenazi B. Benzene exposure near the U.S. permissible limit is associated with sperm aneuploidy. Environ Health Perspect. 2010 Jun; 118(6):833-9.
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      12. Kuo WL, Das D, Ziyad S, Bhattacharya S, Gibb WJ, Heiser LM, Sadanandam A, Fontenay GV, Hu Z, Wang NJ, Bayani N, Feiler HS, Neve RM, Wyrobek AJ, Spellman PT, Marton LJ, Gray JW. A systems analysis of the chemosensitivity of breast cancer cells to the polyamine analogue PG-11047. BMC Med. 2009; 7:77.
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      13. Garbe JC, Bhattacharya S, Merchant B, Bassett E, Swisshelm K, Feiler HS, Wyrobek AJ, Stampfer MR. Molecular distinctions between stasis and telomere attrition senescence barriers shown by long-term culture of normal human mammary epithelial cells. Cancer Res. 2009 Oct 1; 69(19):7557-68.
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      14. Mirzoeva OK, Das D, Heiser LM, Bhattacharya S, Siwak D, Gendelman R, Bayani N, Wang NJ, Neve RM, Guan Y, Hu Z, Knight Z, Feiler HS, Gascard P, Parvin B, Spellman PT, Shokat KM, Wyrobek AJ, Bissell MJ, McCormick F, Kuo WL, Mills GB, Gray JW, Korn WM. Basal subtype and MAPK/ERK kinase (MEK)-phosphoinositide 3-kinase feedback signaling determine susceptibility of breast cancer cells to MEK inhibition. Cancer Res. 2009 Jan 15; 69(2):565-72.
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      15. Lowe XR, Bhattacharya S, Marchetti F, Wyrobek AJ. Early brain response to low-dose radiation exposure involves molecular networks and pathways associated with cognitive functions, advanced aging and Alzheimer's disease. Radiat Res. 2009 Jan; 171(1):53-65.
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      16. Lowe XR, Marchetti F, Lu X, Wyrobek AJ. Molecular stress response in the CNS of mice after systemic exposure to interferon-alpha, ionizing radiation and ketamine. Neurotoxicology. 2009 Mar; 30(2):261-8.
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      17. Marchetti F, Bishop J, Lowe X, Wyrobek AJ. Chromosomal mosaicism in mouse two-cell embryos after paternal exposure to acrylamide. Toxicol Sci. 2009 Jan; 107(1):194-205.
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      18. Straume T, Amundson SA, Blakely WF, Burns FJ, Chen A, Dainiak N, Franklin S, Leary JA, Loftus DJ, Morgan WF, Pellmar TC, Stolc V, Turteltaub KW, Vaughan AT, Vijayakumar S, Wyrobek AJ. NASA Radiation Biomarker Workshop, September 27-28, 2007. Radiat Res. 2008 Sep; 170(3):393-405.
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      19. Young SS, Eskenazi B, Marchetti FM, Block G, Wyrobek AJ. The association of folate, zinc and antioxidant intake with sperm aneuploidy in healthy non-smoking men. Hum Reprod. 2008 May; 23(5):1014-22.
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      20. Marchetti F, Wyrobek AJ. DNA repair decline during mouse spermiogenesis results in the accumulation of heritable DNA damage. DNA Repair (Amst). 2008 Apr 2; 7(4):572-81.
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      21. Marchetti F, Cabreros D, Wyrobek AJ. Laboratory methods for the detection of chromosomal structural aberrations in human and mouse sperm by fluorescence in situ hybridization. Methods Mol Biol. 2008; 410:241-71.
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      22. Marchetti F, Essers J, Kanaar R, Wyrobek AJ. Disruption of maternal DNA repair increases sperm-derived chromosomal aberrations. Proc Natl Acad Sci U S A. 2007 Nov 6; 104(45):17725-9.
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      23. Lowe XR, Lu X, Marchetti F, Wyrobek AJ. The expression of Troponin T1 gene is induced by ketamine in adult mouse brain. Brain Res. 2007 Oct 12; 1174:7-17.
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      24. Sloter ED, Marchetti F, Eskenazi B, Weldon RH, Nath J, Cabreros D, Wyrobek AJ. Frequency of human sperm carrying structural aberrations of chromosome 1 increases with advancing age. Fertil Steril. 2007 May; 87(5):1077-86.
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      25. Wyrobek AJ, Mulvihill JJ, Wassom JS, Malling HV, Shelby MD, Lewis SE, Witt KL, Preston RJ, Perreault SD, Allen JW, Demarini DM, Woychik RP, Bishop JB. Assessing human germ-cell mutagenesis in the Postgenome Era: a celebration of the legacy of William Lawson (Bill) Russell. Environ Mol Mutagen. 2007 Mar; 48(2):71-95.
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      26. Schmid TE, Eskenazi B, Baumgartner A, Marchetti F, Young S, Weldon R, Anderson D, Wyrobek AJ. The effects of male age on sperm DNA damage in healthy non-smokers. Hum Reprod. 2007 Jan; 22(1):180-7.
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      27. Marchetti F, Coleman MA, Jones IM, Wyrobek AJ. Candidate protein biodosimeters of human exposure to ionizing radiation. Int J Radiat Biol. 2006 Sep; 82(9):605-39.
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      28. Tomascik-Cheeseman LM, Lowe XR, Eskenazi B, Kidd S, Nath J, Moore D, Wyrobek AJ. A father of four consecutive trisomic pregnancies with elevated frequencies of associated aneuploid sperm. Am J Med Genet A. 2006 Sep 1; 140A(17):1840-5.
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      29. Sloter E, Schmid TE, Marchetti F, Eskenazi B, Nath J, Wyrobek AJ. Quantitative effects of male age on sperm motion. Hum Reprod. 2006 Nov; 21(11):2868-75.
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      30. Wyrobek AJ, Eskenazi B, Young S, Arnheim N, Tiemann-Boege I, Jabs EW, Glaser RL, Pearson FS, Evenson D. Advancing age has differential effects on DNA damage, chromatin integrity, gene mutations, and aneuploidies in sperm. Proc Natl Acad Sci U S A. 2006 Jun 20; 103(25):9601-6.
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      31. Marchetti F, Pearson FS, Bishop JB, Wyrobek AJ. Etoposide induces chromosomal abnormalities in mouse spermatocytes and stem cell spermatogonia. Hum Reprod. 2006 Apr; 21(4):888-95.
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      32. Coleman MA, Yin E, Peterson LE, Nelson D, Sorensen K, Tucker JD, Wyrobek AJ. Low-dose irradiation alters the transcript profiles of human lymphoblastoid cells including genes associated with cytogenetic radioadaptive response. Radiat Res. 2005 Oct; 164(4 Pt 1):369-82.
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      33. Silver EW, Eskenazi B, Evenson DP, Block G, Young S, Wyrobek AJ. Effect of antioxidant intake on sperm chromatin stability in healthy nonsmoking men. J Androl. 2005 Jul-Aug; 26(4):550-6.
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      34. Marchetti F, Wyrobek AJ. Mechanisms and consequences of paternally-transmitted chromosomal abnormalities. Birth Defects Res C Embryo Today. 2005 Jun; 75(2):112-29.
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      35. Wyrobek AJ, Schmid TE, Marchetti F. Cross-species sperm-FISH assays for chemical testing and assessing paternal risk for chromosomally abnormal pregnancies. Environ Mol Mutagen. 2005 Mar-Apr; 45(2-3):271-83.
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      36. Eskenazi B, Kidd SA, Marks AR, Sloter E, Block G, Wyrobek AJ. Antioxidant intake is associated with semen quality in healthy men. Hum Reprod. 2005 Apr; 20(4):1006-12.
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      37. Wyrobek AJ, Schmid TE, Marchetti F. Relative susceptibilities of male germ cells to genetic defects induced by cancer chemotherapies. J Natl Cancer Inst Monogr. 2005; (34):31-5.
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      38. Zudova D, Wyrobek AJ, Bishop J, Marchetti F. Impaired fertility in T-stock female mice after superovulation. Reproduction. 2004 Nov; 128(5):573-81.
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      39. Motin VL, Georgescu AM, Fitch JP, Gu PP, Nelson DO, Mabery SL, Garnham JB, Sokhansanj BA, Ott LL, Coleman MA, Elliott JM, Kegelmeyer LM, Wyrobek AJ, Slezak TR, Brubaker RR, Garcia E. Temporal global changes in gene expression during temperature transition in Yersinia pestis. J Bacteriol. 2004 Sep; 186(18):6298-305.
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      40. Tomascik-Cheeseman LM, Coleman MA, Marchetti F, Nelson DO, Kegelmeyer LM, Nath J, Wyrobek AJ. Differential basal expression of genes associated with stress response, damage control, and DNA repair among mouse tissues. Mutat Res. 2004 Jul 11; 561(1-2):1-14.
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      41. Schmid TE, Brinkworth MH, Hill F, Sloter E, Kamischke A, Marchetti F, Nieschlag E, Wyrobek AJ. Detection of structural and numerical chromosomal abnormalities by ACM-FISH analysis in sperm of oligozoospermic infertility patients. Hum Reprod. 2004 Jun; 19(6):1395-400.
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      42. Sloter E, Nath J, Eskenazi B, Wyrobek AJ. Effects of male age on the frequencies of germinal and heritable chromosomal abnormalities in humans and rodents. Fertil Steril. 2004 Apr; 81(4):925-43.
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      43. Marchetti F, Bishop JB, Cosentino L, Moore D, Wyrobek AJ. Paternally transmitted chromosomal aberrations in mouse zygotes determine their embryonic fate. Biol Reprod. 2004 Mar; 70(3):616-24.
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      44. Hill FS, Marchetti F, Liechty M, Bishop J, Hozier J, Wyrobek AJ. A new FISH assay to simultaneously detect structural and numerical chromosomal abnormalities in mouse sperm. Mol Reprod Dev. 2003 Oct; 66(2):172-80.
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      45. Yin E, Nelson DO, Coleman MA, Peterson LE, Wyrobek AJ. Gene expression changes in mouse brain after exposure to low-dose ionizing radiation. Int J Radiat Biol. 2003 Oct; 79(10):759-75.
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      46. Glaser RL, Broman KW, Schulman RL, Eskenazi B, Wyrobek AJ, Jabs EW. The paternal-age effect in Apert syndrome is due, in part, to the increased frequency of mutations in sperm. Am J Hum Genet. 2003 Oct; 73(4):939-47.
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      47. Barton TS, Wyrobek AJ, Hill FS, Robaire B, Hales BF. Numerical chromosomal abnormalities in rat epididymal spermatozoa following chronic cyclophosphamide exposure. Biol Reprod. 2003 Oct; 69(4):1150-7.
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      48. Eskenazi B, Wyrobek AJ, Sloter E, Kidd SA, Moore L, Young S, Moore D. The association of age and semen quality in healthy men. Hum Reprod. 2003 Feb; 18(2):447-54.
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      49. Perreault SD, Aitken RJ, Baker HW, Evenson DP, Huszar G, Irvine DS, Morris ID, Morris RA, Robbins WA, Sakkas D, Spano M, Wyrobek AJ. Integrating new tests of sperm genetic integrity into semen analysis: breakout group discussion. Adv Exp Med Biol. 2003; 518:253-68.
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      50. Frias S, Van Hummelen P, Meistrich ML, Lowe XR, Hagemeister FB, Shelby MD, Bishop JB, Wyrobek AJ. NOVP chemotherapy for Hodgkin's disease transiently induces sperm aneuploidies associated with the major clinical aneuploidy syndromes involving chromosomes X, Y, 18, and 21. Cancer Res. 2003 Jan 1; 63(1):44-51.
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      51. Marchetti F, Wyrobek AJ. PAINT/DAPI analysis of mouse zygotes to detect paternally transmitted chromosomal aberrations. Adv Exp Med Biol. 2003; 518:131-45.
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      52. Tiemann-Boege I, Navidi W, Grewal R, Cohn D, Eskenazi B, Wyrobek AJ, Arnheim N. The observed human sperm mutation frequency cannot explain the achondroplasia paternal age effect. Proc Natl Acad Sci U S A. 2002 Nov 12; 99(23):14952-7.
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      53. Sorensen KJ, Attix CM, Christian AT, Wyrobek AJ, Tucker JD. Adaptive response induction and variation in human lymphoblastoid cell lines. Mutat Res. 2002 Aug 26; 519(1-2):15-24.
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      54. Rubes J, Vozdova M, Robbins WA, Rezacova O, Perreault SD, Wyrobek AJ. Stable variants of sperm aneuploidy among healthy men show associations between germinal and somatic aneuploidy. Am J Hum Genet. 2002 Jun; 70(6):1507-19.
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      55. Eskenazi B, Wyrobek AJ, Kidd SA, Lowe X, Moore D, Weisiger K, Aylstock M. Sperm aneuploidy in fathers of children with paternally and maternally inherited Klinefelter syndrome. Hum Reprod. 2002 Mar; 17(3):576-83.
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      56. Tomascik-Cheeseman L, Marchetti F, Lowe X, Shamanski FL, Nath J, Pedersen RA, Wyrobek AJ. CENP-B is not critical for meiotic chromosome segregation in male mice. Mutat Res. 2002 Jan 15; 513(1-2):197-203.
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      57. Lowe X, Eskenazi B, Nelson DO, Kidd S, Alme A, Wyrobek AJ. Frequency of XY sperm increases with age in fathers of boys with Klinefelter syndrome. Am J Hum Genet. 2001 Nov; 69(5):1046-54.
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      58. Schmid TE, Lowe X, Marchetti F, Bishop J, Haseman J, Wyrobek AJ. Evaluation of inter-scorer and inter-laboratory reliability of the mouse epididymal sperm aneuploidy (m-ESA) assay. Mutagenesis. 2001 May; 16(3):189-95.
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      59. Marchetti F, Bishop JB, Lowe X, Generoso WM, Hozier J, Wyrobek AJ. Etoposide induces heritable chromosomal aberrations and aneuploidy during male meiosis in the mouse. Proc Natl Acad Sci U S A. 2001 Mar 27; 98(7):3952-7.
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      60. Kidd SA, Eskenazi B, Wyrobek AJ. Effects of male age on semen quality and fertility: a review of the literature. Fertil Steril. 2001 Feb; 75(2):237-48.
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      61. Sloter ED, Lowe X, Moore II DH, Nath J, Wyrobek AJ. Multicolor FISH analysis of chromosomal breaks, duplications, deletions, and numerical abnormalities in the sperm of healthy men. Am J Hum Genet. 2000 Oct; 67(4):862-72.
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      62. Marchetti F, Lowe X, Bishop J, Wyrobek AJ. Absence of selection against aneuploid mouse sperm at fertilization. Biol Reprod. 1999 Oct; 61(4):948-54.
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      63. Holland N, Ahlborn T, Turteltaub K, Markee C, Moore D, Wyrobek AJ, Smith MT. Acrylamide causes preimplantation abnormalities in embryos and induces chromatin-adducts in male germ cells of mice. Reprod Toxicol. 1999 May-Jun; 13(3):167-78.
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      64. Baumgartner A, Van Hummelen P, Lowe XR, Adler ID, Wyrobek AJ. Numerical and structural chromosomal abnormalities detected in human sperm with a combination of multicolor FISH assays. Environ Mol Mutagen. 1999; 33(1):49-58.
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      65. Rubes J, Lowe X, Moore D, Perreault S, Slott V, Evenson D, Selevan SG, Wyrobek AJ. Smoking cigarettes is associated with increased sperm disomy in teenage men. Fertil Steril. 1998 Oct; 70(4):715-23.
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      66. Mascio LN, Yuen BK, Kegelmeyer WP, Matsumoto K, Briner J, Wyrobek AJ. Advances in the automated detection of metaphase chromosomes labeled with fluorescence dyes. Cytometry. 1998 Sep 1; 33(1):10-8.
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      67. Lowe XR, de Stoppelaar JM, Bishop J, Cassel M, Hoebee B, Moore D, Wyrobek AJ. Epididymal sperm aneuploidies in three strains of rats detected by multicolor fluorescence in situ hybridization. Environ Mol Mutagen. 1998; 31(2):125-32.
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      68. Titenko-Holland N, Ahlborn T, Lowe X, Shang N, Smith MT, Wyrobek AJ. Micronuclei and developmental abnormalities in 4-day mouse embryos after paternal treatment with acrylamide. Environ Mol Mutagen. 1998; 31(3):206-17.
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      69. Van Hummelen P, Manchester D, Lowe X, Wyrobek AJ. Meiotic segregation, recombination, and gamete aneuploidy assessed in a t(1;10)(p22.1;q22.3) reciprocal translocation carrier by three- and four-probe multicolor FISH in sperm. Am J Hum Genet. 1997 Sep; 61(3):651-9.
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      70. Robbins WA, Meistrich ML, Moore D, Hagemeister FB, Weier HU, Cassel MJ, Wilson G, Eskenazi B, Wyrobek AJ. Chemotherapy induces transient sex chromosomal and autosomal aneuploidy in human sperm. Nat Genet. 1997 May; 16(1):74-8.
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      71. Vine MF, Setzer RW, Everson RB, Wyrobek AJ. Human sperm morphometry and smoking, caffeine, and alcohol consumption. Reprod Toxicol. 1997 Mar-Jun; 11(2-3):179-84.
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      72. Wyrobek AJ, Schrader SM, Perreault SD, Fenster L, Huszar G, Katz DF, Osorio AM, Sublet V, Evenson D. Assessment of reproductive disorders and birth defects in communities near hazardous chemical sites. III. Guidelines for field studies of male reproductive disorders. Reprod Toxicol. 1997 Mar-Jun; 11(2-3):243-59.
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      73. Fenster L, Katz DF, Wyrobek AJ, Pieper C, Rempel DM, Oman D, Swan SH. Effects of psychological stress on human semen quality. J Androl. 1997 Mar-Apr; 18(2):194-202.
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      74. Marchetti F, Lowe X, Bishop J, Wyrobek AJ. Induction of chromosomal aberrations in mouse zygotes by acrylamide treatment of male germ cells and their correlation with dominant lethality and heritable translocations. Environ Mol Mutagen. 1997; 30(4):410-7.
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      75. Baulch JE, Lowe XR, Bishop JB, Wyrobek AJ. Evidence for a parent-of-origin effect on sperm aneuploidy in mice carrying Robertsonian translocations as analyzed by fluorescence in situ hybridization. Mutat Res. 1996 Dec; 372(2):269-78.
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      76. Adler ID, Bishop J, Lowe X, Schmid TE, Schriever-Schwemmer G, Xu W, Wyrobek AJ. Spontaneous rates of sex chromosomal aneuploidies in sperm and offspring of mice: a validation of the detection of aneuploid sperm by fluorescence in situ hybridization. Mutat Res. 1996 Dec; 372(2):259-68.
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      77. Marchetti F, Lowe X, Moore DH, Bishop J, Wyrobek AJ. Paternally inherited chromosomal structural aberrations detected in mouse first-cleavage zygote metaphases by multicolour fluorescence in situ hybridization painting. Chromosome Res. 1996 Dec; 4(8):604-13.
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      78. Van Hummelen P, Lowe XR, Wyrobek AJ. Simultaneous detection of structural and numerical chromosome abnormalities in sperm of healthy men by multicolor fluorescence in situ hybridization. Hum Genet. 1996 Nov; 98(5):608-15.
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      79. Lowe X, O'Hogan S, Moore D, Bishop J, Wyrobek A. Aneuploid epididymal sperm detected in chromosomally normal and Robertsonian translocation-bearing mice using a new three-chromosome FISH method. Chromosoma. 1996 Oct; 105(4):204-10.
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      80. Wyrobek AJ, Adler ID. Detection of aneuploidy in human and rodent sperm using FISH and applications of sperm assays of genetic damage in heritable risk evaluation. Mutat Res. 1996 Jun 10; 352(1-2):173-9.
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      81. Fraga CG, Motchnik PA, Wyrobek AJ, Rempel DM, Ames BN. Smoking and low antioxidant levels increase oxidative damage to sperm DNA. Mutat Res. 1996 Apr 13; 351(2):199-203.
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      82. Musilová P, Lee DA, Stratil A, Cepica S, Rubes J, Lowe X, Wyrobek A. Assignment of the porcine IKBA gene (IkappaBalpha) encoding a cytoplasmic inhibitor of the NF-kappaB to chromosome 7q15-q21 by FISH. Mamm Genome. 1996 Apr; 7(4):323-4.
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      83. Nutley EV, Tcheong AC, Allen JW, Collins BW, Ma M, Lowe XR, Bishop JB, Moore DH, Wyrobek AJ. Micronuclei induced in round spermatids of mice after stem-cell treatment with chloral hydrate: evaluations with centromeric DNA probes and kinetochore antibodies. Environ Mol Mutagen. 1996; 28(2):80-9.
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      84. Bishop JB, Dellarco VL, Hassold T, Ferguson LR, Wyrobek AJ, Friedman JM. Aneuploidy in germ cells: etiologies and risk factors. Environ Mol Mutagen. 1996; 28(3):159-66.
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      85. Wyrobek AJ, Aardema M, Eichenlaub-Ritter U, Ferguson L, Marchetti F. Mechanisms and targets involved in maternal and paternal age effects on numerical aneuploidy. Environ Mol Mutagen. 1996; 28(3):254-64.
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      86. Lowe X, Collins B, Allen J, Titenko-Holland N, Breneman J, van Beek M, Bishop J, Wyrobek AJ. Aneuploidies and micronuclei in the germ cells of male mice of advanced age. Mutat Res. 1995 Oct; 338(1-6):59-76.
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      87. Wyrobek A, Lowe X, Pinkel D, Bishop J. Aneuploidy in late-step spermatids of mice detected by two-chromosome fluorescence in situ hybridization. Mol Reprod Dev. 1995 Feb; 40(2):259-66.
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      88. Robbins WA, Baulch JE, Moore D, Weier HU, Blakey D, Wyrobek AJ. Three-probe fluorescence in situ hybridization to assess chromosome X, Y, and 8 aneuploidy in sperm of 14 men from two healthy groups: evidence for a paternal age effect on sperm aneuploidy. Reprod Fertil Dev. 1995; 7(4):799-809.
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      89. MacGregor JT, Tucker JD, Eastmond DA, Wyrobek AJ. Integration of cytogenetic assays with toxicology studies. Environ Mol Mutagen. 1995; 25(4):328-37.
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      90. Wyrobek AJ, Robbins WA, Mehraein Y, Pinkel D, Weier HU. Detection of sex chromosomal aneuploidies X-X, Y-Y, and X-Y in human sperm using two-chromosome fluorescence in situ hybridization. Am J Med Genet. 1994 Oct 15; 53(1):1-7.
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      91. Stanker LH, Wyrobek A, McKeown C, Balhorn R. Identification of the binding site of two monoclonal antibodies to human protamine. Mol Immunol. 1993 Dec; 30(18):1633-8.
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      92. Robbins WA, Segraves R, Pinkel D, Wyrobek AJ. Detection of aneuploid human sperm by fluorescence in situ hybridization: evidence for a donor difference in frequency of sperm disomic for chromosomes 1 and Y. Am J Hum Genet. 1993 Apr; 52(4):799-807.
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      93. Wyrobek AJ. Methods and concepts in detecting abnormal reproductive outcomes of paternal origin. Reprod Toxicol. 1993; 7 Suppl 1:3-16.
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      94. Stanker LH, McKeown C, Balhorn R, Lee C, Mazrimas J, Goralka M, Wyrobek A. Immunological evidence for a P2 protamine precursor in mature rat sperm. Mol Reprod Dev. 1992 Dec; 33(4):481-8.
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      95. Eskenazi B, Wyrobek AJ, Fenster L, Katz DF, Sadler M, Lee J, Hudes M, Rempel DM. A study of the effect of perchloroethylene exposure on semen quality in dry cleaning workers. Am J Ind Med. 1991; 20(5):575-91.
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      96. Eskenazi B, Fenster L, Hudes M, Wyrobek AJ, Katz DF, Gerson J, Rempel DM. A study of the effect of perchloroethylene exposure on the reproductive outcomes of wives of dry-cleaning workers. Am J Ind Med. 1991; 20(5):593-600.
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      97. Wyrobek AJ, Alhborn T, Balhorn R, Stanker L, Pinkel D. Fluorescence in situ hybridization to Y chromosomes in decondensed human sperm nuclei. Mol Reprod Dev. 1990 Nov; 27(3):200-8.
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      98. Tucker JD, Wyrobek AJ, Ashworth LK, Christensen ML, Burton GV, Carrano AV, Everson RB. Induction, accumulation, and persistence of sister chromatid exchanges in women with breast cancer receiving cyclophosphamide, adriamycin, and 5-fluorouracil chemotherapy. Cancer Res. 1990 Aug 15; 50(16):4951-6.
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      99. Bigbee WL, Wyrobek AJ, Langlois RG, Jensen RH, Everson RB. The effect of chemotherapy on the in vivo frequency of glycophorin A 'null' variant erythrocytes. Mutat Res. 1990 Mar; 240(3):165-75.
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      100. Moruzzi JF, Wyrobek AJ, Mayall BH, Gledhill BL. Quantification and classification of human sperm morphology by computer-assisted image analysis. Fertil Steril. 1988 Jul; 50(1):142-52.
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      101. Wyrobek AJ. Application of human sperm parameters for monitoring. Prog Clin Biol Res. 1986; 207:101-20.
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      102. Meistrich ML, Goldstein LS, Wyrobek AJ. Long-term infertility and dominant lethal mutations in male mice treated with adriamycin. Mutat Res. 1985 Oct; 152(1):53-65.
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      103. Rosenberg MJ, Wyrobek AJ, Ratcliffe J, Gordon LA, Watchmaker G, Fox SH, Moore DH, Hornung RW. Sperm as an indicator of reproductive risk among petroleum refinery workers. Br J Ind Med. 1985 Feb; 42(2):123-7.
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      104. Brandriff B, Gordon L, Ashworth L, Watchmaker G, Moore D, Wyrobek AJ, Carrano AV. Chromosomes of human sperm: variability among normal individuals. Hum Genet. 1985; 70(1):18-24.
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      105. Halamka J, Gray JW, Gledhill BL, Lake S, Wyrobek AJ. Estimation of the frequency of malformed sperm by slit scan flow cytometry. Cytometry. 1984 Jul; 5(4):333-8.
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      106. Balhorn R, Weston S, Thomas C, Wyrobek AJ. DNA packaging in mouse spermatids. Synthesis of protamine variants and four transition proteins. Exp Cell Res. 1984 Feb; 150(2):298-308.
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      107. Wyrobek AJ. Identifying agents that damage human spermatogenesis: abnormalities in sperm concentration and morphology. IARC Sci Publ. 1984; (59):387-402.
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      108. Wyrobek AJ, Watchmaker G, Gordon L. An evaluation of sperm tests as indicators of germ-cell damage in men exposed to chemical or physical agents. Teratog Carcinog Mutagen. 1984; 4(1):83-107.
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      109. Brandriff B, Gordon L, Ashworth L, Watchmaker G, Carrano A, Wyrobek A. Chromosomal abnormalities in human sperm: comparisons among four healthy men. Hum Genet. 1984; 66(2-3):193-201.
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      110. Wyrobek AJ, Watchmaker G, Gordon L. An evaluation of sperm tests as indicators of germ-cell damage in men exposed to chemical or physical agents. Prog Clin Biol Res. 1984; 160:385-405.
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      111. Da Cunha MF, Meistrich ML, Ried HL, Gordon LA, Watchmaker G, Wyrobek AJ. Active sperm production after cancer chemotherapy with doxorubicin. J Urol. 1983 Nov; 130(5):927-30.
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      112. Pinkel D, Gledhill BL, Van Dilla MA, Lake S, Wyrobek AJ. Radiation-induced DNA content variability in mouse sperm. Radiat Res. 1983 Sep; 95(3):550-65.
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      113. Wyrobek AJ, Gordon LA, Burkhart JG, Francis MW, Kapp RW, Letz G, Malling HV, Topham JC, Whorton MD. An evaluation of human sperm as indicators of chemically induced alterations of spermatogenic function. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res. 1983 May; 115(1):73-148.
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      114. Wyrobek AJ, Gordon LA, Burkhart JG, Francis MW, Kapp RW, Letz G, Malling HV, Topham JC, Whorton MD. An evaluation of the mouse sperm morphology test and other sperm tests in nonhuman mammals. A report of the U.S. Environmental Protection Agency Gene-Tox Program. Mutat Res. 1983 May; 115(1):1-72.
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      115. Wyrobek AJ. Methods for evaluating the effects of environmental chemicals on human sperm production. Environ Health Perspect. 1983 Feb; 48:53-9.
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      116. Moore DH, Bennett DE, Kranzler D, Wyrobek AJ. Quantitative methods of measuring the sensitivity of the mouse sperm morphology assay. Anal Quant Cytol. 1982 Sep; 4(3):199-206.
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      117. da Cunha MF, Meistrich ML, Haq MM, Gordon LA, Wyrobek AJ. Temporary effects of AMSA (4'-(9-acridinylamino) methanesulfon-m-anisidide) chemotherapy on spermatogenesis. Cancer. 1982 Jun 15; 49(12):2459-62.
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      118. Benaron DA, Gray JW, Gledhill BL, Lake S, Wyrobek AJ, Young IT. Quantification of mammalian sperm morphology by slit-scan flow cytometry. Cytometry. 1982 Mar; 2(5):344-9.
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      119. Wyrobek AJ, Brodsky J, Gordon L, Moore DH, Watchmaker G, Cohen EN. Sperm studies in anesthesiologists. Anesthesiology. 1981 Nov; 55(5):527-32.
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      120. Wyrobek AJ, Watchmaker G, Gordon L, Wong K, Moore D, Whorton D. Sperm shape abnormalities in carbaryl-exposed employees. Environ Health Perspect. 1981 Aug; 40:255-65.
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      121. Wyrobek AJ. Changes in mammalian sperm morphology after X-ray and chemical exposures. Genetics. 1979 May; 92(1 Pt 1 Suppl):s105-19.
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      122. Balhorn R, Gledhill BL, Wyrobek AJ. Mouse sperm chromatin proteins: quantitative isolation and partial characterization. Biochemistry. 1977 Sep 6; 16(18):4074-80.
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      123. Wyrobek AJ, Meistrich ML, Furrer R, Bruce WR. Physical characteristics of mouse sperm nuclei. Biophys J. 1976 Jul; 16(7):811-25.
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      124. Wyrobek AJ, Heddle JA, Bruce WR. Chromosomal abnormalities and the morphology of mouse sperm heads. Can J Genet Cytol. 1975 Dec; 17(4):675-81.
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      125. Wyrobek AJ, Bruce WR. Chemical induction of sperm abnormalities in mice. Proc Natl Acad Sci U S A. 1975 Nov; 72(11):4425-9.
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      126. Bruce WR, Furrer R, Wyrobek AJ. Abnormalities in the shape of murine sperm after acute testicular x-irradiation. Mutat Res. 1974 Jun; 23(3):381-6.
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      127. Loir M, Wyrobek A. Density separation of mouse spermatid nuclei. Exp Cell Res. 1972 Nov; 75(1):261-5.
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